J Otolaryngol Ophthalmol Shandong Univ ›› 2018, Vol. 32 ›› Issue (5): 50-52.doi: 10.6040/j.issn.1673-3770.0.2018.112

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Assessment of psychopathological characteristics in 30 patients with sudden sensorineural hearing loss

ZHU Wenyan1, JIN Xin1, SHE Wandong2, MA Yongchi1   

  1. Drum Tower Hospital Affiliated to Nanjing University, Nanjing 210008, Jiangsu, China
  • Received:2018-03-02 Online:2018-09-20 Published:2018-09-20

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Abstract: Objective To investigate the psychopathological characteristics of patients with sudden sensorineural hearing loss(SSHL). Methods The Symptom Checklist-90(SCL-90)scores and plasma 5-hydroxytryptamine(5-HT)levels were determined in 30 patients with SSHL and 20 healthy adult controls. Results The total and average SCL-90 scores were 121.69±22.53 and 1.35±0.25, respectively, in the SSHL group, and 111.65±15.25 and 1.23±0.25 in the control group. There were no significant differences in total and average scores between the two groups(P>0.05). However, the SCL-90 scores for the four dimensions of somatization, depression, paranoia, and other(sleep, diet, etc.)were higher in the SSHL group than in the control group, and the difference was statistically significant(P< 0.05). The plasma 5-HT level in the SSHL group was significantly lower than in the normal control group(P<0.05)and the SCL-90 score was negatively correlated with the plasma 5-HT (r=-0.507, P=0.004). Conclusion Compared with healthy adults, patients with SSHL show a tendency toward mild psychopathology. Patients with SSHL have clear evidence of depression, paranoia, and sleep disorders, and significantly lower plasma 5-HT levels compared to healthy adults.

Key words: Depression, 5-hydroxytryptamine, Symptom Checklist-90, Sudden hearing loss, Psychopathological characteristics

CLC Number: 

  • R764.437
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