Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (4): 75-85.doi: 10.6040/j.issn.1673-3770.0.2022.189

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Meta-analysis of randomized controlled trials of acupoint application in treatment of children with allergic rhinitis

BI Xiaoyun1, MA Benxu2, WANG Xinru1, LI Xuhao1, YANG Jiguo1   

  1. 1. School of Acupuncture and Massage, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong, China2. Department of Acupuncture and Moxibustion, Qingdao Central Hospital, Qingdao 266000, Shandong, China
  • Published:2023-07-27

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Abstract: Objective To evaluate the efficacy of acupoint application in the treatment of children with allergic rhinitis(AR)by meta-analysis. Methods PubMed, the Cochrane Library, CNKI, VIP, WanFang, and CBM, were searched comprehensively for randomized controlled trials(RCT)of acupoint application used in treatment of children with allergic rhinitis, with retrieval time set from establishment of each database to April 17, 2022. RevMan 5.3 and Stata 14.0 were used to analyze relevant outcome indicators. Results A total of 19 RCTs were included, with a total sample size of 1669 cases. Meta-analysis results showed that the effective rate of acupoint application combined with traditional Chinese medicine in the treatment of children with allergic rhinitis was significantly better than the control group of traditional Chinese medicine alone(RR=1.12, 95%CI ［1.03,1.21］, P=0.006). The effective rate of acupoint application combined with Western medicine in the treatment of children with allergic rhinitis was significantly better than Western medicine alone(RR=1.28, 95%CI ［1.14,1.44］, P<0.001). The clinical effect of acupoint application alone was significantly better than Western medicine alone(RR=1.23, 95%CI ［1.15,1.31］, P<0.001). The clinical effect of simple acupoint application is equivalent to that of simple application of traditional Chinese medicine(RR=1.45, 95%CI ［0.84,2.49］, P=0.18). Acupoint application and Western medicine can both reduce Eosinophil and Immunoglobulin E levels, but there were no differences in reduction effects. Acupoint application can significantly reduce Interleukin-4 levels, enhance Interferon-γ levels, and improve clinical symptoms. Conclusion Acupoint application therapy is effective, safe, and reliable for clinical treatment of children with allergic rhinitis, and can be widely used.

Key words: Acupoint application, Children with allergic rhinitis, Meta-analysis

CLC Number: 

  • R765
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