Abstract:

Objective   To observe the effect of prior laser and triamcinolone acetonide  on vitrectomy of proliferative diabetic retinopathy. Methods   The study included 110 patients (132 eyes) with proliferative diabetic retinopathy who underwent vitrectomy. The 65 patients (72 eyes) who underwent prior and standard laser treatment accepted vitrectomy and triamcinolone acetonide (4mg/0.1mL) was injected into the vitreous. The 45 patients (60 eyes) who never underwent standard laser treatment accepted vitrectomy and triamcinolone acetonide (4mg/0.1mL) was injected into the vitreous one week before the vitrectomy. All the patients were followed up for 3 months, and the clinical curative effect was summarized. Results   The natural visual acuity and best corrected vision acuity had significant differences 1 month after operation than before operation. The postoperative inflammatory reaction of anterior chamber was mild in the most patients. Postoperative intraocular press increased in 41eyes(31.1%), and turned normal after the patients used medicine. Conclusion   The early standard laser treatment combined with triamcinolone acetonide before and during operation is helpful to decrease the hemorrhage and other serious complications.

Key words: Triamcinolone acetonide, Proliferativediabetic retinopathy, Laser, Vitrectomy