Abstract:

Objective    To investigate the effect of corneal endotheliitis on the number and morphology of corneal endothelial cells. Methods    The study group included 20 cases (20eyes), including 13 cases of disciform endotheliitis and 7 cases of diffuse endotheliitis. All patients accepted systemic and topical antiviral medications combined with corticosteroids. The endothelium cells checked by corneal endothelial microscope were analyzed for cell density, coefficient variation of cell size and hexgonality 4-6 weeks after the patients were cured. The healthy eyes were set as the control group. Results        Compared with the control group, the treatment group had lower corneal endothelial cell density and hexagonal cell ratio and higher variation coefficient. Compared with the disciform endotheliitis group, the diffuse endotheliitis group had lower corneal endothelial cell density and hexagonal cell ratio and higher variation coefficient. Conclusion    Corneal endotheliitis can damage the corneal endothelial cells, leading to significant changes in their number and morphology. There were distinctions between different types.

Key words: Corneal endotheliitis, Treatment, Corneal endothelial microscope