JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (1): 83-87.doi: 10.6040/j.issn.1673-3770.0.2015.341

Previous Articles     Next Articles

Variation of visual acuity and fundus in type 2 diabetic patients after phacoemulsification surgery.

SHAO Na1, ZHANG Han   

  1. Department of Ophthalmology, 1. Jining No.1 Peoples Hospital, Jining 272000, Shandong, China;2. The Second Hospital of Shandong University, Jinan 250033, Shangdong, China
  • Received:2015-08-16 Online:2016-02-16 Published:2016-02-16

PDF (PC)

804

Abstract: Objective To evaluate the risk factors of diabetic retinopathy(DR)progression by observing the variation of visual acuity and fundus in type 2 diabetic patients after phacoemulsification and intraocular lens implantation. Methods A total of 50 patients with type 2 diabetes mellitus accompanied by non-proloferative diabetic retinopathy(NPDR)who needed to undergo phacoemulsification and intraocular lens implantation for the single eye were collected as research objects. Operative eyes and non-operatives were respectively as surgery and non-surgery groups. On 1, 7 days and 1, 3 months after surgery, both the best corrected visual acuity(BCVA)and optical coherence tomography(OCT)in macular region were conducted, and fundus fluorescein angiography(FFA)was also performed 3 months after surgery. The DR progression-related risk factors were analyzed. Results The visual acuity in surgery group improved obviously 1 d-3 months after surgery(P<0.01), but BCVA 3 months after surgery had the decreasing trend. The incidence of postoperative macular edema and DR progression rate in surgery group were higher than in non-surgery group, with statistical significance(P<0.05 or P<0.01). Logistic regression analysis research results displayed that glycosylated hemoglobin(OR=21.423), course of diabetes mellitus(OR=9.061)and NPDR degree(OR=2.486)were the risk factors of DR progression. Conclusion The BCVA of patients with NPDR in type 2 diabetes mellitus improves dramatically after phacoemulsification and intraocular lens implantation, but decreases slightly 3 months after surgery. Long course of diabetes mellitus, worse control of blood glucose and preoperative aggravation of DR are the risk factors of postoperative DR progression.

Key words: Type 2 diabetes mellitus, Phacoemulsification, Optical coherence tomography, Best corrected visual acuity, Diabetic retinopathy

CLC Number: 

  • R776.1
[1] 中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2010年版)[J]. 中国医学前沿杂志(电子版), 2011, 3(6): 54-109.
[2] 刘巨平, 胡博杰, 程朝晖, 等. 白内障超声乳化吸除术对糖尿病视网膜病变进展影响的Meta分析[J]. 眼科, 2013, 22(6):378-382. LIU Juping, HU Bojie, CHENG Zhaohui, et al. The influence of cataract phacoemulsification on progression of diabetic retinopathy and diabetic macular Meta-analysis[J]. Ophthalmol, 2013, 22(6):378-382.
[3] Ostri C. Intraocular surgery in a large diabetes patient population: risk factors and surgical results[J]. Acta Ophthalmol, 2014, 92(Thesis1):1-13.
[4] Lara-Smalling A, Cakiner-Egilmez T. Diabetes and cataract surgery: preoperative risk factors and positive nursing interventions[J]. Insight, 2014, 39(2):18-20.
[5] Henricsson M, Heijl A, Janzon L. Diabetic retinopathy before and after cataract surgery[J]. Ophthalmol, 1996, 80(9):789-793.
[6] Varma R, Macias G L, Torres M, et al. Biologic risk factors associated with diabetic retinopathy[J]. Ophthalmol, 2007, 7:1332-1340.
[7] 谢茂松, 郑永征, 徐国兴. 眼前节内眼模拟手术诱发血眼屏障破坏的大鼠动物模型[J]. 中华眼底病杂志, 2012, 28(1):68-72. XIE Maosong, ZHENG Yongzheng, XU Guoxing. Rat model of blood-ocular barrier breakdown induced by anterior segment intraocular analogic surgery[J]. Chin J Ocul Fund Dis, 2012, 28(1):68-72.
[8] 周媛, 崔浩, 刘洪涛, 等. 糖尿病对血-视网膜屏障超微结构影响的研究进展[J]. 国际眼科杂志, 2014, 7(7):1220-1222. ZHOU Yuan, CUI Hao, LIU Hongtao, et al. Research progress of diabetes on the ultrastructure of blood retina barrier[J]. Inter Eye Sci, 2014, 14(7):1220-1222.
[1] WANG Xinmeng, JI Junya, YU Haonan, FU Hongchen, WANG Xiang, ZHENG Zekun, LI Yan, ZHONG Yingying. Analysis of refractive prediction accuracy after phacoemulsification combined with goniosynechialysis in acute Angle closure glaucoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2026, 40(2): 74-79.
[2] ZHAO Juan, JIAO Wanzhen, ZHAO Bojun. Assessment of fundus microcirculation changes in diabetic retinopathy using UWFSS-OCTA [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2026, 40(2): 80-86.
[3] ZHU Mingqiong, LI Zheng, LIU Ru, TIAN Tao, PENG Jingli, LYU Qianyi, TAN Huaxia. The application of AI screening system based on OCT/OCTA in the evaluation of the effect of anti VEGF treatment in patients with diabetes macular edema [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2026, 40(1): 68-73.
[4] SUN Qingzhu, SHEN Jian, CHEN Xing, WU Yanbing, ZENG Lun. The role of metabolic indicators in predicting ranibizumab efficacy in diabetic macular edema [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2026, 40(1): 74-81.
[5] LI Shiqiang, MA Yan, WANG Jiawei. Advances in clinical applications of optical coherence tomography angiography in systemic diseases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2026, 40(1): 127-134.
[6] ZHANG Lu, WANG Yongjing, JIA Jun, ZHAO Jiannan, ZHAO Fang. Spectral domain optical coherence tomography imaging characteristics in patients with initial onset floaters [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(1): 85-88.
[7] HUANG Jiao, PENG Changfu. Progress in objective evaluation of thyroid-related eye disease activity [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(1): 171-178.
[8] XIN Meng, JI Fang, DAI Chunhua, ZHANG Jing, LIU Shu. Effect of sodium hyaluronate and balanced salt solution on ocular surface protection during minimally invasive vitreorentinal surgery [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(5): 58-65.
[9] MA Jiling, WANG Xiaoming, LI Yan, MU Yanxiao, JIN Lin, KONG Hui, YANG Naifu, DANG Guangfu. Evaluation of three different aspheric intraocular lens tilts and decentrations in capsular bags after cataract surgery based on CASIA2 [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(4): 76-85.
[10] CHANG Weiwei, JIAO Wanzhen, CUI Yanyan, ZHAO Jie, LIU Zhaoqiang, ZHAO Bojun. Research progress of diabetic macular ischaemia [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(3): 130-136.
[11] HE Jing, LEI Chunyan, ZHANG Meixia. Association of glycosylated hemoglobin variation index with diabetic retinopathy severity [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(2): 34-40.
[12] WU Lili, QU Yi. Application of optical tomography angiography and artificial intelligence in choroidal neovascularization secondary to pathologic myopia [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(2): 144-149.
[13] WANG Xinyu, GAO Lifen, LU Hui, SONG Wenqi, YANG Yu. Related retinal manifestations in Parkinson's disease [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(2): 156-162.
[14] LUN Yingjun, CHEN Chen, GAO Hongcheng, FAN Qinglin, TAI Renqing. Role of Toll-like receptor 4/nuclear transcription factor-κB channels in diabetic retinopathy [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(2): 163-168.
[15] LIU Jiangchuan, LI Pengwei, GUO Jianqiang, LU Huiqin. Application of optical coherence tomography in idiopathic epiretinal membrane [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(1): 138-142.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd