山东大学耳鼻喉眼学报 ›› 2013, Vol. 27 ›› Issue (6): 53-56.doi: 10.6040/j.issn.1673-3770.0.2013.189

• 论著 • 上一篇    下一篇

腺样体肥大儿童伴变应性鼻炎与分泌性中耳炎的相关性分析

吴佳欐,陈淑梅,田欣,赵利敏,倪坤,顾美珍,陈佳瑞,周佳蕾,李晓艳   

  1. 上海市儿童医院耳鼻咽喉头颈外科, 上海 200040
  • 收稿日期:2013-06-23 发布日期:2013-12-16
  • 作者简介:吴佳欐。 Email:wujiali540@hotmail.com

Relationship between allergic rhinitis and secretory otitis media in children with adenoid hypertrophy

WU Jia-li, CHEN Shu-mei, TIAN Xin, ZHAO Li-min, NI Kun, GU Mei-zhen, CHEN Jia-rui, ZHOU Jia-lei, LI Xiao-yan   

  1. Department of Otolaryngology & Head and Neck Surgery, Shanghai Children′s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200040,China
  • Received:2013-06-23 Published:2013-12-16

摘要:

目的    分析腺样体肥大儿童伴分泌性中耳炎(OME)与变应性鼻炎(AR)发病的相关性。方法    回顾性分析12岁以下870例腺样体肥大患儿的病史,分析AR、咽鼓管功能不良及OME的相关性。结果    本组腺样体肥大患儿中AR发病率为30.11%,AR在不同年龄组中的发病率差异有统计学意义,随着年龄增加,发病率逐渐升高(P<0.01)。6岁以内发生咽鼓管功能障碍及OME的概率高,其中1~3岁组发生分泌性中耳炎的概率最大(P<0.01)。春季OME发病率高(P<0.001)。与不伴AR患者相比,伴有AR患儿患咽鼓管功能不良的概率增加了0.4倍(P=0.042);但患有OME的检出率减少了32%(P=0.0472)。结论    在腺样体肥大患儿中,多种因素使咽鼓管功能不良乃至OME高发。其中咽鼓管及其周围结构生理、病理、发育特点是最主要的因素,变态反应是次要影响因素。随着年龄增长,前者因逐渐发育完善,致病性降低,后者致病性增高,但总的发病率是逐渐降低的。

关键词: 咽鼓管功能障碍, 腺样体肥大, 分泌性中耳炎, 变应性鼻炎

Abstract:

Objective    To investigate the correlation between otitis media with effusion (OME) and allergic rhinitis(AR) in children with adenoid hypertrophy. Methods    870 patients under 12 years old with adenoid hypertrophy were collected for current retrospective analysis. Association between AR and eustachian tube dysfunction and OME was calculated by Chi-square test and logistic regression model. Results        The prevalence of allergic rhinitis children with adenoid hypertrophy was 30.11%. The prevalence of allergic rhinitis in different age groups had significant difference and increased with age(P< 0.01). The probability of eustachian tube dysfunction and OME occurring in patients younger than 6 years was high and reached the highest in 1 to 3 years old patients(P=0.001). OME prevalence was higher in spring(P=0.001) than in other seasons. The prevalence of allergic rhinitis with eustachian tube dysfunction was 1.4 times higher than those without allergic rhinitis(P=0.042). The detection rate of OME with AR was 0.32 times hihger than that of OME without AR(P=0.052). Conclusion    The structures, physiological and pathological characteristics of eustachian tube are the main factors causing eustachian tube dysfunction and high incidence of OME. Allergy maybe the secondary factor. With children′s growth,the pathogenicity of the former becomes lower and the latter becomes higher, but the incidence of otitis media with effusion decreases.

Key words: Otitis media with effusion, Eustachian tube dysfunction, Adenoid hypertrophy, Allergic rhinitis

中图分类号: 

  • R764.21
[1] 王坛,武珂,李连庆,宫丽丽. 皮下免疫治疗注射后出现全身不良反应的伴发因素及处理[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 71-74.
[2] 卢汉桂,林歆胜,姚丹勉,魏永新,李创伟. 变应性鼻炎大鼠IL-35的表达及对辅助性T细胞免疫调节的影响[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 66-70.
[3] 王驰,刘星,孔磊,洪兴和,宁博. 鼻内镜下等离子射频消融术对合并鼻窦炎的小儿腺样体肥大患者疗效及鼻腔黏膜纤毛清除功能的影响[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 78-81.
[4] 周鼎坤,蔡郁,田艳华,滕博,冯青杰. Crouzon儿童腺样体切除术后并发Grisel综合征一例[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 119-120.
[5] 浦洪波,杜晓东. 无锡地区2 000例变应性鼻炎变应原检测结果分析[J]. 山东大学耳鼻喉眼学报, 2018, 32(4): 105-107.
[6] 陈鸣,俞雪飞. 浅谈伴有变应性鼻炎的慢性鼻窦炎的治疗[J]. 山东大学耳鼻喉眼学报, 2018, 32(3): 18-22.
[7] 吴湘萍. 患者管理方式对变应性鼻炎舌下含服粉尘螨滴剂疗效的影响[J]. 山东大学耳鼻喉眼学报, 2018, 32(3): 68-72.
[8] 王岩,师晓丽. 变态反应与儿童OSAHS的关系[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 14-18.
[9] 高进良,年婉清,李烁. 鼻内镜手术联合鼻用糖皮质激素治疗腺样体肥大性[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 38-42.
[10] 李松,王宗贵,杨景朴,张竹萍. 鼻内镜下翼管神经切断术进展[J]. 山东大学耳鼻喉眼学报, 2018, 32(1): 72-76.
[11] 谢日林,张志平. 布地奈德体位滴鼻治疗伴腺样体肥大的小儿分泌性中耳炎31例[J]. 山东大学耳鼻喉眼学报, 2018, 32(1): 65-67.
[12] 郅莉莉,宋道亮. 嗜酸性粒细胞及IL5在上颌窦后鼻孔息肉与鼻息肉中表达的差异[J]. 山东大学耳鼻喉眼学报, 2017, 31(4): 43-46.
[13] 万文锦,王文,程雷. 尘螨变应性鼻炎皮下免疫治疗与舌下免疫治疗的荟萃分析[J]. 山东大学耳鼻喉眼学报, 2017, 31(4): 103-108.
[14] 程雷,钱俊俊,田慧琴. 变应性鼻炎研究的若干进展[J]. 山东大学耳鼻喉眼学报, 2017, 31(3): 1-3.
[15] 许昱,陶泽璋. 重视变应性鼻炎药物治疗的规范化和个体化[J]. 山东大学耳鼻喉眼学报, 2017, 31(3): 4-8.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!