准分子激光上皮瓣下角膜磨镶术矫治高度近视

山东大学耳鼻喉眼学报

准分子激光上皮瓣下角膜磨镶术矫治高度近视

刘美光¹，王传富¹，陶祥臣²，牟国营²

1. 青岛大学医学院附属医院眼科，山东青岛 266003；2. 济南市中心医院，山东大学临床医学院眼科，山东济南 250013

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-10-24 发布日期:2007-10-24
通讯作者: 刘美光

Laser-assisted subepithelial keratectomy for the correction of high myopia

LIU Mei-guang¹， WANG Chuan-fu¹，TAO Xiang-chen²， MU Guo-ying²

1. Department of Ophthalmology, Affiliated Hospital of Medical College of Qingdao University;2. Department of Ophthalmology,Jinan Central Hospital, School of Clinical Medicine, Shandong University

Received:1900-01-01 Revised:1900-01-01 Online:2007-10-24 Published:2007-10-24
Contact: LIU Mei-guang

摘要/Abstract

摘要： 目的评价准分子激光上皮瓣下角膜磨镶术（LASEK）矫治高度近视的疗效。方法选取高度近视患者27例（54眼），术前近视等效球镜为-6.00～-14.00D，平均（-8.75±1.27）D。观察术后角膜上皮修复时间、术后视力、角膜上皮下雾状混浊（Haze）、角膜地形图及屈光度数，随访时间为6个月。结果所有术眼术中及术后均无严重并发症发生。术后角膜上皮修复时间平均为（3.71±0.26）d。术后3d，裸眼视力≥0.5者48眼（88.9％），≥0.8者19眼（35.2％），术后7d，裸眼视力≥0.5者54眼（100.0％），≥0.8者47眼（87.0％），术后6个月，裸眼视力均达到或超过术前最佳矫正视力。术后1、3、6个月等效球镜均在-0.50～＋0.50D之间，术后1、3、6个月角膜Haze发生率分别为13眼（24.1%）、7眼（13.0%）、2眼（3.7%），但均小于2级，不影响视力恢复。结论 LASEK治疗高度近视视力恢复好且稳定，无明显角膜上皮下雾状混浊及屈光回退。

关键词: 准分子激光上皮瓣下角膜磨镶术, 近视, 视力, 角膜上皮下雾状混浊

Abstract: Objective To investigate the effect of laserassisted subepithelial keratectomy（LASEK）for the correction of high myopia. Methods LASEK was performed on 54 eyes of 27 myopia patients. The preoperative mean spherical (MSE) was -6.00～-14.00D, average（-8.75±1.27）D. Postoperative uncorrected visual acuity(UCVA), refractive power, time of epithelial healing and corneal haze were all recorded. Patients were followedup for 6 months. Results No serious complications occurred. The epithelium was healed in a mean （3.71±0.26）d. 3 days after the operations, the UCVA≥0.5 was found in 88.9%(48/54) and ≥0.8 in 35.2% (19/54). 7 days after the operations, the UCVA≥0.5 was found in 100%(54/54) and ≥0.8 in 87.0% (47/54). 6 months after the operations the UCVA was equal with or better than the preoperative best corrected visual acuity (BCVA). 1, 3 and 6 months after the operations, corneal haze was found in 13 eyes（24.1%）, 7 eyes（13.0%） and 2 eyes（3.7%）respectively but it was below grade 2 and had no effect on visual acuity. Conclusion LASEK is a safe, effective, stable and predictable surgery for myopia.

Key words: Laser-assisted subepithelial keratomileusis, Myopia, Visual acuity, Corneal haze

中图分类号:

R778

刘美光,王传富,陶祥臣,牟国营 . 准分子激光上皮瓣下角膜磨镶术矫治高度近视[J]. 山东大学耳鼻喉眼学报, 2007, 21(5): 465-467 .

LIU Mei-guang,WANG Chuan-fu,TAO Xiang-chen,MU Guo-ying . Laser-assisted subepithelial keratectomy for the correction of high myopia[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2007, 21(5): 465-467 .

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