Stargardt病的荧光素眼底血管造影和光相干断层扫描特征

山东大学耳鼻喉眼学报

Stargardt病的荧光素眼底血管造影和光相干断层扫描特征

潘雪梅，王兴荣，袁明俊

山东中医药大学眼科中心山东施尔明眼科医院，济南 250002

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-04-24 发布日期:2008-04-24
通讯作者: 潘雪梅

Fundus angiography with fluorescein and optical coherence tomography in Stargardt′s disease

PAN Xue-mei, WANG Xing-rong, YUAN Ming-jun

Eye Center of Shandong University of Traditional Chinese Medicine， Shandong Shierming Eye Hospital， Jinan 250002, China

Received:1900-01-01 Revised:1900-01-01 Online:2008-04-24 Published:2008-04-24
Contact: PAN Xue-mei

摘要/Abstract

摘要： 目的观察Stargardt病的荧光素眼底血管造影(FFA)与光相干断层扫描（OCT）图像特征。方法对Stargardt病患者7例14眼拍摄彩色眼底图像，其中6例12眼行FFA检查，7例14眼行黄斑区OCT检查。结果检眼镜检查4眼黄斑区色素紊乱呈颗粒状，FFA表现为暗脉络膜背景荧光，黄斑区呈现透见荧光，牛眼状高荧光，眼底检查8眼黄斑区表现为卵圆形变性区并呈金箔样反光，后极部出现黄色斑点，FFA表现为后极部斑点状荧光，晚期呈强荧光。OCT检查发现14眼神经上皮层变薄甚至缺失。结论Stargardt病黄斑区神经上皮层萎缩，FFA表现为黄斑区透见荧光，OCT表现为视网膜厚度变薄，二者的临床应用为该病诊断提供了有效方法。

关键词: Stargardt病, 荧光造影, 光学相干断层扫描

Abstract: To determine the characteristics of the results of fluorescein angiography (FFA) and optical coherence tomography (OCT) in Stargardt′s disease（STGD）. Methods7 patients (14 eyes) with Stargardt′s were diagnosed by ocular fundus photochromy, and 6 patients (12 eyes) received FFA and 7 patients (14 eyes) received OCT. ResultsPigment was disordered at the macula in 4 eyes by ophthalmoscopy. A “dark choroid" and window defect (bulls-eye pattern hyperfluorescence) were found by FFA, yellow-white fleck lesions were found in the pole in 8 eyes by ophthalmoscopy, also hypofluorescent became more apparent in the later phase by FFA, and the retina was reduced or deleted in 14 eyes by OCT. 　ConclusionFFA combined with OCT is useful for studying the clinical features and pathological mechanism of Stargardt's disease.

Key words: Fluorescein angiography, Optical coherence tomographyStargardt , Stargardt′s disease

中图分类号:

R774.5

潘雪梅,王兴荣,袁明俊 . Stargardt病的荧光素眼底血管造影和光相干断层扫描特征[J]. 山东大学耳鼻喉眼学报, 2008, 22(2): 162-164 .

PAN Xue-mei,WANG Xing-rong,YUAN Ming-jun . Fundus angiography with fluorescein and optical coherence tomography in Stargardt′s disease[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(2): 162-164 .

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