山东大学耳鼻喉眼学报

• 无栏目 • 上一篇    下一篇

耳部炎性疾病的细菌学及药物敏感性分析

张秀秀,张秋贵,朱富高,张晓恒
  

  1. (青岛大学医学院附属医院耳鼻咽喉头颈外科, 山东 青岛 266203)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-02-16 发布日期:2009-02-16

Pathogenic bacterium and its resistance in aural inflammatory diseases

ZHANG Xiuxiu, ZHANG Qiugui, ZHU Fugao, ZHANG Xiaoheng
  

  1. (Department of Otolaryngology, Affiliated Hospital of Qingdao University, Qingdao 266203, Shandong, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-02-16 Published:2009-02-16

摘要: 目的了解慢性化脓性中耳炎及外耳道炎主要病原菌的分布及药物敏感性,用以指导临床用药。方法取238例慢性化脓性中耳炎及外耳道炎患者外耳道深部或鼓室内脓性分泌物,行细菌及霉菌培养和药物敏感试验。结果分离出病原菌206株,包括金黄色葡萄球菌 (34.95%)、耐甲氧西林凝固酶阴性葡萄球菌(20.38%)、绿脓杆菌(7.28%)、真菌 (18.45%)。药物敏感性因菌种而异。结论慢性化脓性中耳炎及外耳道炎的病原菌以金黄色葡萄球菌为主,耐甲氧西林凝固酶阴性葡萄球菌次之,真菌比例明显增高。不同病原菌对药物的敏感性及耐药性不同,对临床常用抗生素存在耐药性。对耳部炎性疾病应行分泌物培养及药物敏感试验,以便采取针对性治疗。 

关键词: 中耳炎, 化脓性, 外耳道炎, 细菌培养, 药敏试验

Abstract: To explore the bacteriology of chronic suppurative otitis media and diffuse external otitis and examine antibiotic sensitivity of a certain isolated bacterium for guiding appropriate use of antibiotics. MethodsMiddle ear or deep external acoustic meatus purulence were collected from 238 patients with chronic suppurative otitis media or diffuse external otitis and cultured for bacteria, fungi and an antimicrobial susceptibility test. ResultsThere were 206 strains of microbes isolated from the 238 cases. Staphylococcus aureus accounted for 34.95%, methicillinresistant coagulase negative staphylococcus for 20.38%, pseudomonas aeruginosa for 7.28%, and fungi for 18.45%. The antibiotic sensitivity was variable among the isolated bacterial strains. ConclusionStaphylococcus aureus is the main pathogenic bacteria of chronic suppurative otitis media and diffuse external otitis, and methicillinresistant coagulase negative staphylococcus is the second. The infective rate of fungi increased. Pathogenic bacteria have resistance to commonly used antibiotics. We should perform bacterial culture, fungal culture, and antimicrobial susceptibility tests for patients with chronic suppurative otitis media and diffuse external otitis in order to choose appropriate antibiotics.

中图分类号: 

  • R746.21
[1] 谢日林,张志平. 布地奈德体位滴鼻治疗伴腺样体肥大的小儿分泌性中耳炎31例[J]. 山东大学耳鼻喉眼学报, 2018, 32(1): 65-67.
[2] 马钊恩, 翟锦明, 廖礼兵, 杨震. 咽鼓管球囊扩张术治疗慢性分泌性中耳炎的短期疗效观察[J]. 山东大学耳鼻喉眼学报, 2017, 31(5): 54-56.
[3] 吴允刚,张辉,刘黎明,庞太忠,李晓瑜. 鼓膜激光打孔治疗分泌性中耳炎20例[J]. 山东大学耳鼻喉眼学报, 2017, 31(1): 85-87.
[4] 杜丽君,童军,陈文文,邓亚新,蔡勋华,单良. 单侧听力耳中耳炎手术经验再探讨[J]. 山东大学耳鼻喉眼学报, 2016, 30(6): 8-10.
[5] 孙娜综述,陈晓平审校. 咽喉反流与耳鼻咽喉科疾病[J]. 山东大学耳鼻喉眼学报, 2016, 30(6): 85-89.
[6] 沈莉. 碳酸氢钠联合氟康唑注射液治疗真菌性外耳道炎35例[J]. 山东大学耳鼻喉眼学报, 2016, 30(6): 22-23.
[7] 刘斌,江育玲,肖旭平. 钛质人工听小骨在开放式鼓室成形术中的疗效观察与应用体会[J]. 山东大学耳鼻喉眼学报, 2016, 30(4): 80-83.
[8] 朱江彬, 孙秀芹, 南兵卫, 郝宗生. 5%碳酸氢钠液与制霉菌素片混合制剂纱条治疗真菌性外耳道炎156例[J]. 山东大学耳鼻喉眼学报, 2015, 29(6): 82-83.
[9] 李兆生, 洪斌, 黄前进, 蒲伟民, 许振跃. 耳源性小脑脓肿2例并文献复习[J]. 山东大学耳鼻喉眼学报, 2015, 29(5): 32-37.
[10] 梁冬泳, 何中扬, 李趣, 邹秀园, 黄岳, 王菊新, 卓勇智. 两种途径鼓室注入地塞米松治疗分泌性中耳炎的临床研究[J]. 山东大学耳鼻喉眼学报, 2015, 29(5): 29-31.
[11] 孙昌志, 刘文龙, 李琰, 罗仁忠. 双耳感音神经性聋患儿合并分泌性中耳炎的临床诊治[J]. 山东大学耳鼻喉眼学报, 2015, 29(4): 11-14.
[12] 刘谦虚, 张志钢, 赵晓明, 李海鸥. 中青年与老年慢性化脓性中耳炎及中耳胆脂瘤患者听力学特点及区别[J]. 山东大学耳鼻喉眼学报, 2015, 29(3): 24-28.
[13] 黄雄超, 廖首本, 董仕婷, 钟海建, 覃永前. 氟康唑注射液耳浴治疗真菌性外耳道炎71例[J]. 山东大学耳鼻喉眼学报, 2015, 29(3): 29-30.
[14] 李慎玲, 张孝田, 姜晓丹, 黄天桥, 郭鸽, 梁大鹏. 53例慢性化脓性中耳炎患者分泌物细菌培养及药敏学分析[J]. 山东大学耳鼻喉眼学报, 2015, 29(3): 31-34.
[15] 陈泽, 钟兆棠, 梁敏志. 前壁外耳道-鼓膜瓣应用于开放式鼓室成形术31例[J]. 山东大学耳鼻喉眼学报, 2014, 28(6): 11-15.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!