鼻窦清合剂对兔鼻窦炎上颌窦黏膜形态影响的电镜观察

山东大学耳鼻喉眼学报 ›› 2009, Vol. 23 ›› Issue (3): 39-42.

鼻窦清合剂对兔鼻窦炎上颌窦黏膜形态影响的电镜观察

顾真宁云红李艳刘峰

1. 山东中医药大学附属医院耳鼻喉科，济南 250011； 2. 山东中医药大学，济南 250014； 3. 烟台海港医院耳鼻喉科，山东烟台 264002；4. 沂源县中医医院耳鼻喉科，山东沂源 256100

收稿日期:2009-02-20 修回日期:2009-05-12 出版日期:2009-06-16 发布日期:2009-06-16
作者简介:顾真，女，教授，主要从事耳鼻咽喉疾病的中医治疗。Email:guzhen66@sina.com

Effects of Bidouqing Heji on morphological changes in maxillary sinus mucosa of rabbits with nasosinusitis

GU Zhen, NING Yun-Gong, LI Yan, LIU Feng

1. Department of Otolaryngology, Affiliated Hospital of Shangdong University of Traditional Chinese Medicine, Jinan 250011, China;
2. Shangdong University of Traditional Chinese Medicine, Jinan 250011, China;
3. Department of Otolaryngology, Yantai Haigang Hospital, Yantai 264002, Shandong, China;
4. Department of Otolaryngology, Yiyuan Hospital of Traditional Chinese Medicine, Yiyuan 256100, Shandong, China

Received:2009-02-20 Revised:2009-05-12 Online:2009-06-16 Published:2009-06-16

摘要/Abstract

摘要：

目的观察鼻窦清合剂对兔鼻窦炎上颌窦黏膜炎症的影响。方法行窦口不完全堵塞加用金黄色葡萄球菌建立急慢性鼻窦炎动物模型后，予以鼻窦清合剂高、低剂量灌胃治疗，并设立空白组、模型组、鼻渊舒（鼻渊舒口服液灌胃）组作为对照；急性期用药1周，慢性期用药2周后，分别通过透射电子显微镜观察 ,比较各组兔上颌窦黏膜形态结构的变化。结果鼻窦清合剂低剂量组黏膜形态最接近正常组，且急性各组优于慢性各组。结论鼻窦清合剂可改善兔上颌窦炎症。

关键词: 鼻窦清合剂;鼻窦炎;黏膜;形态学

Abstract:

Objective To observe the effects of Bidouqing Heji on the morphology of maxillary sinus mucosa of rabbits with nasosinusitis. Methods Nasosinusitis models were established by a modified method of Hinni's. Fifty-four rabbits were randomly divided into nine groups: the normal, acute and chronic models, acute and chronic groups with Biyuanshu, and Bidouqing Heji of the low and high dosage groups. Transmission electron microscopy was used to observe morphological changes of maxillary sinus mucosa of each group. ResultsThere was no statistic difference between the Bidouqing Heji of the low dosage group and the normal control group, and between the acute groups and the chronic groups. ConclusionBidouqing Heji could improve the morphological changes of maxillary sinus mucosa of rabbits with nasosinusitis.

Key words: Bidouqing Heji; Nasosinusitis; Mucosa; Morphology

中图分类号:

R765.4

顾真宁云红李艳刘峰. 鼻窦清合剂对兔鼻窦炎上颌窦黏膜形态影响的电镜观察[J]. 山东大学耳鼻喉眼学报, 2009, 23(3): 39-42.

GU Zhen, NING Yun-Gong, LI Yan, LIU Feng. Effects of Bidouqing Heji on morphological changes in maxillary sinus mucosa of rabbits with nasosinusitis[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2009, 23(3): 39-42.

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