山东东部地区女性喉癌患者的临床特点

山东大学耳鼻喉眼学报 ›› 2010, Vol. 24 ›› Issue (2): 8-10.

山东东部地区女性喉癌患者的临床特点

刘章，孙彦，华辉，陈志俊，李薇，孙文海

青岛大学医学院附属医院耳鼻咽喉头颈外科，山东青岛 266003

收稿日期:2010-03-01 修回日期:2010-04-06 出版日期:2010-04-16 发布日期:2010-04-16
通讯作者: 孙彦（1962- ），男，主任医师，教授，硕士生导师，主要从事头颈部肿瘤和咽喉部疾病的研究。 Email：sunyanohns@yahoo.com.cn
作者简介:刘章（1984- ），男，硕士研究生，主要从事头颈部肿瘤临床和基础方面研究。 Email:entliuzhang@yahoo.cn

Clinical features of laryngeal carcinoma in females in the east of Shandong Province

LIU Zhang, SUN Yan, HUA Hui, CHEN Zhijun, LI Wei, SUN Wenhai

Department of Otorhinolaryngology ＆ Head and Neck Surgery, The Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, Shandong, China

Received:2010-03-01 Revised:2010-04-06 Online:2010-04-16 Published:2010-04-16

摘要/Abstract

摘要：

目的探讨山东东部地区女性喉癌患者的临床特点。方法对22例女性喉癌患者资料进行回顾性分析，其中声门上型8例，声门型13例，声门下型1例；按2002年AJCC标准进行分期：Ⅰ期10例，Ⅱ期2例，Ⅲ期4例，Ⅳ期6例。行喉部分切除术14例，喉全切除术6例，同时行颈清扫术10例，术后放疗10例。单纯放疗2例。生存率采用直接法计算。结果行手术治疗的20例中，治疗后满3年者11例，失访2例，无瘤生存8例，3年直接生存率72.7%；治疗后满5年者6例，失访1例，无瘤生存5例，5年直接生存率83.3%；行单纯放射治疗的2例分别于治疗后9个月和1年死于复发。结论女性喉癌发病率较低，声门上型喉癌构成比相对较高，部分女性喉癌患者与吸烟有关，女性喉癌患者的多原发癌值得重视

关键词: 喉肿瘤；癌，鳞状细胞；女性；外科手术；存活率

Abstract:

Objective To investigate the clinical features of laryngeal carcinoma in females in the East of Shandong Province. Methods Twenty-two female patients with laryngeal carcinoma were retrospectively analyzed, including 8 cases of supraglottic carcinoma, 13 cases of glottic carcinoma and 1 case of subglottic carcinoma. According to AJCC（2002）, there were 10 cases in stageⅠ, 2 cases in stageⅡ,4 cases in stage Ⅲ, and 6 cases in stage Ⅳ. Partial laryngectomy was performed in 14 patients and total laryngectomy in 6 patients. 10 patients underwent neck dissection synchronously. Radiotherapy was performed in 10 patients after surgery. And 2 patients only received radiotherapy. The direct method was used to calculate the survival rate. Results Among the 20 patients who received surgery, 11 were followed up for more than 3 years: 2 were missed and 8 were disease-free survival. The 3-year survival rate was 72.7%. Only 6 patients were followed up for more than 5 years: 1 was missed and 5 were disease-free survived. The 5-year survival rate was 83.3%. The two patients who only received radiotherapy died because of the relapse in 9 months and 1 year after treatment respectively. Conclusion Laryngeal carcinoma in females has a low incidence. Supraglottic carcinoma is relatively common in female patients. Smoking is an important factor in some females. Multiple primary carcinomas should be focused on in females.

Key words: Laryngeal neoplasms; Carcinoma, Squamous cell; Female; Surgery; Survival rate

中图分类号:

R739.6

刘章，孙彦，华辉，陈志俊，李薇，孙文海. 山东东部地区女性喉癌患者的临床特点[J]. 山东大学耳鼻喉眼学报, 2010, 24(2): 8-10.

LIU Zhang, SUN Yan, HUA Hui, CHEN Zhijun, LI Wei, SUN Wenhai. Clinical features of laryngeal carcinoma in females in the east of Shandong Province[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2010, 24(2): 8-10.

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