山东大学耳鼻喉眼学报 ›› 2010, Vol. 24 ›› Issue (3): 64-66.

• 论文 • 上一篇    下一篇

四种手术方法治疗翼状胬肉168眼

王玉霞,肖瑛,孙洪义,高雪,刘景,陈国玲,杨丽霞   

  1. 山东大学第二医院眼科,济南  250033
  • 收稿日期:2009-11-19 修回日期:2010-04-28 出版日期:2010-06-16 发布日期:2010-06-16
  • 通讯作者: 肖瑛。Email: yingxiao99@yahoo.cn
  • 作者简介:王玉霞(1985 ),女,硕士研究生,主要从事角膜、眼表疾病及儿童屈光不正斜视弱视方面的研究。Email: xiami19850412@126.com

Four surgical treatments of pterygium on 168 eyes

WANG Yuxia, XIAO Ying, SUN Hongyi, GAO Xue, LIU Jing, CHEN Guoling, YANG Lixia   

  1. Department of Ophthalmology, Second Hospital of Shandong University, Jinan  250033,  China
  • Received:2009-11-19 Revised:2010-04-28 Online:2010-06-16 Published:2010-06-16

摘要:

目的  探讨单纯翼状胬肉切除术、翼状胬肉切除联合丝裂霉素C、翼状胬肉切除联合带角膜缘的结膜瓣移植术、翼状胬肉切除联合羊膜移植术四种方法治疗胬肉的手术效果。方法  分析翼状胬肉患者158例(168眼)接受不同手术方式的手术效果。其中,A组(41眼)接受单纯翼状胬肉切除术,B组(42眼)接受单纯胬肉切除联合丝裂霉素C术,C组(44眼)接受翼状胬肉切除联合带角膜缘的结膜瓣移植术,D组(41眼)接受翼状胬肉切除联合羊膜移植术。术后随访 6~12个月。结果  A组复发率 17.1% ,B组复发率为9.5%,C组复发率4.5%,D组复发率为4.9% 。A组的复发率和其它三组比较差异有统计学意义 (P﹤0.05);B、C组、B、D组、C、D组复发率的比较差异无统计学意义(P﹥0.05)。C组的并发症较其他三组的并发症少。 结论  翼状胬肉切除联合带角膜缘的结膜瓣移植术是目前值得推广的手术方式,具有经济实用、复发率低、角膜上皮愈合快、并发症少等优点。

关键词: 翼状胬肉 ;丝裂霉素C;带角膜缘的结膜瓣移植; 羊膜移植

Abstract:

Objectiv  eTo compare the therapeutic effects of simple pterygium excision,  pterygium excision combined with mitomycin C, limbus corneae stem cell transplantation, or amniotic membrane transportation on pterygium.  Methods  168 eyes of 158 patients were divided into four groups, i.e.  groups A,B, C and D, in terms of  applied treatments.41 eyes (group A),42 eyes (group B), 44 eyes (group C)  and 41 eyes ( group D) were treated with simple pterygium excision, pterygium excision combined with mitomycin C, limbus corneae stem cell transplantation, or  amniotic membrane transportation,  respectively.The patients were followed up from 6 months to one year.Results  The recurrence rates of pterygium in groups A,B, C and D were 17.1%,9.5%, 4.5% and 4.9%,respectively.The difference between group A and the other three groups(B,C and D)was statistically significant (P<0.05),whereas there was no statistical significance between group B & C ,group  B & D and group C & D. Group C had fewer complications than the other three groups. Conclusion  Pterygium excision combined with limbus corneae stem cell transplantation is the preferable methods while it demonstrates better costeffectiveness, lowere recurrence rate, shorter corneal epithelial healing time and fewer complications.

Key words: Pterygium; Mitomycin C; Conjunctival flap with corneal Limbus transplantation; Amniotic membrane transplantation

中图分类号: 

  • R777.33
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