Smart Plug泪小管塞治疗水液缺乏型干眼症临床初步观察

山东大学耳鼻喉眼学报 ›› 2011, Vol. 25 ›› Issue (1): 63-66.

Smart Plug泪小管塞治疗水液缺乏型干眼症临床初步观察

郭丽1，袁方2，李斌1

1. 武警山东总队医院眼科, 济南 250014； 2. 武警山东总队干休所,济南 250012

收稿日期:2010-08-05 修回日期:2010-11-05 出版日期:2011-02-16 发布日期:2011-02-16
作者简介:郭丽（1979- ）,女,硕士研究生,主治医师，现工作单位为武警山东总队医院,主要从事白内障、泪道、斜弱视等方面的研究。 Email:guoli-2651@163. com

Initial clinical observation of Smart Plug lacrimal plug in the treatment of aqueous tear deficiency dry eye

GUO Li1, YUAN Fang2, LI Bin1

1. Department of Ophthalmology, Shandong PAP Corps Hospital, Jinan 250014, China;
2. Veteran sanatorium Of Shandong PAP Corps, Jinan 250012, China

Received:2010-08-05 Revised:2010-11-05 Online:2011-02-16 Published:2011-02-16

摘要/Abstract

摘要：

目的观察Smart Plug泪小管塞治疗水液缺乏型干眼症的临床疗效。方法应用Smart Plug 泪小管塞治疗水液缺乏型干眼症患者42例（84 眼），随访5～15个月，平均8.3个月，根据SchirmerI 试验（SIT）、泪膜破裂时间（TBUT）、角膜荧光素染色(FL)观察临床疗效。结果 ①治疗前后SIT分别为(3.41±0.60)mm和(5.75±0.44)mm（P＜0.05）； ②治疗前后TBUT分别为(3.75±1.26)s和(6.46±1.47)s（P＜0.05）；③FL评分分别为(2.45±0.06)分和(0.04±0.02)分（P＜0.05）；④患者主观症状改善。结论 Smart Plug 泪小管塞治疗水液缺乏型干眼症具有明确的疗效，对于水液缺乏型干眼病患者在眼表发生不可逆性损害之前即应早期行泪道栓塞治疗。

关键词: 干眼症；泪小管塞

Abstract:

Objective To evaluate the clinical efficacy of SmartPlug lacrimal plug in the treatment of aqueous tear deficiency dry eye. Methods SmartPlug lacrimal plugs were inserted to treat 42 cases of aqueous tear deficiency dry eye (84 eyes). All patients were followed-up for 5-15 months（average 8.3 months）. Schirmer I test (SIT) ，tear breakup time (TBUT), and fluorescent of cornea (FL) were used to evaluate the clinical efficacy. Results ①Pre- and posttreatment SIT were 3.41±0.60mm and 5.75±0.44mm(P<0.05), respectively; ② Pre- and post-treatment TBUT were 3.75±1.26 seconds and 6.46±1.47 seconds (P<0.05), respectively; ③Pre- and posttreatment FL were 2.45±0.06 and 0.04±0.02 (P<0.05), respectively;④The subjective symptoms improved in most patients. Conclusions The SmartPlug lacrimal plug is effective in the treatment of aqueous tear deficiency dry eye. Moreover, it is recommended that lacrimal punctual occlusion should be done before irreversible damages of the ocular surface.

Key words: Dry eye; Lacrimal plug

中图分类号:

R777.21

郭丽1，袁方2，李斌1. Smart Plug泪小管塞治疗水液缺乏型干眼症临床初步观察[J]. 山东大学耳鼻喉眼学报, 2011, 25(1): 63-66.

GUO Li1, YUAN Fang2, LI Bin1. Initial clinical observation of Smart Plug lacrimal plug in the treatment of aqueous tear deficiency dry eye[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2011, 25(1): 63-66.

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