山东大学耳鼻喉眼学报 ›› 2012, Vol. 26 ›› Issue (1): 29-30.

• 论文 • 上一篇    下一篇

鼻内镜下经咽鼓管鼓室内注入地塞米松辅助治疗难治性突发性耳聋

吴允刚,李晓瑜,庞太忠,高福平,李珊,王彩华,张永红,张辉,黄萌萌   

  1. 济宁医学院附属医院耳鼻咽喉头颈外科, 山东 济宁 272029
  • 收稿日期:2011-09-10 出版日期:2012-02-16 发布日期:2012-02-16
  • 通讯作者: 李晓瑜,主任医师。 Email: lxyent@163.com
  • 作者简介:吴允刚,主治医师。 Email:wyg0607@163.com
  • 基金资助:

    山东省自然基金资助项目(ZR2010HL045)

Intratympanic dexamethasone injections through pharyngotympanic tube for sudden sensorineural hearing loss

WU Yun-gang, LI Xiao-yu, PANG Tai-zhong, GAO Fu-ping, LI Shan, WANG Cai-hua, ZHANG Hui, HUANG Meng-meng   

  1. Department of Otolaryngology-Head and Neck Surgery, the Affiliated Hospital of Jining Medical College, Jining 272029, Shandong, Chnia
  • Received:2011-09-10 Online:2012-02-16 Published:2012-02-16

摘要:

目的   探讨鼻内镜下经咽鼓管鼓室内注入地塞米松辅助治疗突发性聋(SSNHL)的疗效。方法    对20例常规方法治疗无效的SSNHL患者采用鼻内镜下经咽鼓管鼓室径路注入地塞米松,首次剂量为5mg,此后每天重复注药1次,每次5mg,共7~10次,总剂量35~50mg, 用药期间密切观察记录听力改变、耳鸣及眩晕等情况。结果   20例于治疗完成后复查纯音电测听,痊愈1例;显效3例,听阈平均提高32dB;有效5例,听阈平均提高18dB;无效11例;有效率为45%(9/20)。结论    鼻内镜下经咽鼓管鼓室内注入地塞米松辅助治疗SSNHL疗效好,操作方便,避免全身用药可能产生的不良反应,为常规方法治疗无效的SSNHL患者提供了再次治疗的机会。

关键词: 咽鼓管;鼓室;突发性聋;地塞米松

Abstract:

Objective   To investigate the efficacy of intratympanic dexamethasone injection through the  pharyngotympanic tube (PTIDI)for 20 patients with sudden sensorineural hearing loss(SSNHL). Methods   Deamethasone(5mg) was injected into the middle ear through the pharyngotympanic tube for 20 patients of SSNHL sensorneural hearing loss. The medication was repeated every day until a total of 7-10 doses(3550mg) was reached. Results   The 20 patients were followed up for two weeks. One (5%) recovered completely, Three (15%) demonstrated a 32dBHL improvement in PTA, and 11 (55%) showed no response. Conclusions   PTIDI is a simple and effective treatment for SSNHL. It can be applied to the patients who failed to respond to conventional treatment and can avoided the side effects followed  by highdosage systemic corticostemid treatment.

Key words: Pharyngotympanic tube; Intratympanic; Sudden sensorineural hearing loss; Dexamethasone

中图分类号: 

  • R764
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