青岛地区变应性鼻炎流行病学调查研究

山东大学耳鼻喉眼学报 ›› 2012, Vol. 26 ›› Issue (2): 55-60.

青岛地区变应性鼻炎流行病学调查研究

高荣莉1，丁见2，臧延伟3，闫舒1，刘婷婷1，刘赞刚4，宫相贵5，周晓彬6，李娜1，张念凯1

1.青岛大学医学院附属医院耳鼻咽喉头颈外科，山东青岛 266003； 2.青岛市黄岛区中医医院，山东青岛
266500； 3.莱西市市立医院耳鼻咽喉头颈外科，山东莱西 266600； 4.青岛市城阳区河套街道尚家沟村诊所，
山东青岛 266113； 5.青岛市崂山区云头崮社区诊所，山东青岛 266044； 6.青岛大学流行病学与公共卫生
教研室，山东青岛 266021

收稿日期:2011-09-08 出版日期:2012-04-16 发布日期:2012-04-16
通讯作者: 张念凯，教授，硕士生导师。 Email:znkent@yahoo.com.cn
作者简介:高荣莉，硕士研究生。 Email:gh12122009@126.com

Epidemiological investigation of allergic rhinitis in the Qingdao area

GAO Rong-li1， DING Jian2, ZANG Yan-wei3, YAN Shu1, LIU Ting-ting1, LIU Zan-gang4, GONG Xiang-gui5， ZHOU Xiao-bin6, LI Na1, ZHANG Nian-kai1

1. Department of Otolaryngology, Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, Shandong, China； 2. Traditional Chinese Medicine in the Huangdao area, Qingdao 266500, Shandong, China; 3. Department of Otolaryngology， Municipal Hospital of Laixi City, Laixi 266600, Shandong, China; 4. Clinic of Shang Jia Gou, Hetao Street, Chengyang District in the Qingdao, Qingdao 266113, Shandong, China; 5. Clinic of Yun Tougu, Laoshan Community in Qingdao, Qingdao 266044, Shandong, China; 6.Department of Epidemiology and Public Health of Qingdao University, Qingdao 266021, Shandong, China

Received:2011-09-08 Online:2012-04-16 Published:2012-04-16

摘要/Abstract

摘要：

目的调查青岛地区变应性鼻炎(allergic rhinitis, AR)患病率并分析其相关因素。方法设计“青岛地区变应性鼻炎问卷调查表”。采用多阶段抽样及整群抽样的方法，调查青岛地区常住(5年及5年以上)居民，年龄在5~70岁，均无高血压、糖尿病、风湿性疾病及精神障碍性疾病的居民。共调查2052人：调查分三个阶段：问卷调查阶段，根据问卷结果筛选AR可疑对象，对AR可疑对象进行专科检查及变应原皮肤点刺试验以确诊。根据变应性鼻炎诊断和治疗指南(2009年，武夷山)，对结果进行统计学处理。结果发放问卷总数为2400份，有效问卷为2052份，有效率为85.5%，青岛地区5~70岁居民AR的患病率为12.08%，其中男12.7%，女11.3%，男女患病率差异无统计学意义(χ2=0.918， P>0.05)。农村患病率为8%，城市患病率为15%，城乡患病率差异有统计学意义(χ2=23.86， P<0.05)。按ARIA标准：持续性AR为62%(153/248),季节性AR为38%(95/248)。青岛地区常见变应原依次为粉尘螨、屋尘螨、海虾。结论青岛地区变应性鼻炎患病率为12.08%，变应原主要为粉尘螨、屋尘螨、海虾。AR患病率季节性小于持续性、农村小于城市。

关键词: 鼻炎，变应性；患病率；流行病学研究

Abstract:

Objective To investigate the morbidity of allergic rhinitis(AR) in the Qingdao area and its correlative factors. Methods A questionnaire survey on AR was performed in the Qingdao area. We applied over two-stage sampling and cluster sampling methods to the mental health of permanent residents, excluding hypertension, diabetes mellitus and rheumatic disease, aged from 5-70 years in the Qingdao area including seven district and five cities. Our investigation had three stages： questionnaire survey, screening of suspected AR patients according to the results of the questionnaire, and suspects of AR．Diagnosis criteria of AR were the guide of AR in diagnosis and treatment in 2009. Results 2052 questionnaires were available. The effective rate was 85.5%.The prevalence rate of AR in residents aged from 5-70 was 12.08% in Qingdao City. The difference of prevalence between females 11.3% and males 12.7% was statistically insignificant(χ2=0.918, P>0.05). The difference of prevalence between city 15% and village 8% was statistically significant(χ2=23.86, P<0.05). According to the classification criteria of ARIA in 2001, 95 residents suffered from intermittent AR, while 153 suffered from persistent AR. The most common allergens of AR were dermatophagoides farinae, house dust mite and shrimp. Conclusion The prevalence rate of AR in residents is 12.08%. The most common allergens of AR are dermatophagoides farinae, house dust mite and shrimp. The prevalence rate of seasonal allergic rhinitis is less than sustainable, in the village less than in the city.

Key words: Rhinitis, allergy; Prevalence; Epidemiological studies

中图分类号:

R765.21

高荣莉1，丁见2，臧延伟3，闫舒1，刘婷婷1，刘赞刚4，宫相贵5，周晓彬6，李娜1，张念凯1. 青岛地区变应性鼻炎流行病学调查研究[J]. 山东大学耳鼻喉眼学报, 2012, 26(2): 55-60.

GAO Rong-li1， DING Jian2, ZANG Yan-wei3, YAN Shu1, LIU Ting-ting1, LIU Zan-gang4, GONG Xiang-gui5， ZHOU Xiao-bin6, LI Na1, ZHANG Nian-kai1. Epidemiological investigation of allergic rhinitis in the Qingdao area[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2012, 26(2): 55-60.

参考文献

相关文章 15

[1]	王长青1,李新平1,赵文敏1，王忠1，曾鸿斌1，张华1，刘立中2 . 阿司匹林耐受不良三联征的临床特点[J]. 山东大学耳鼻喉眼学报, 2012, 26(3): 45-47.
[2]	张霞1，夏立军2. 20例慢性鼻-鼻窦炎鼻内镜术后随访及生活质量研究[J]. 山东大学耳鼻喉眼学报, 2012, 26(2): 51-54.
[3]	陈芳,李晓艳. T-bet、TGF-β在过敏性鼻炎中的研究进展[J]. 山东大学耳鼻喉眼学报, 2012, 26(2): 83-86.
[4]	刘杰1，陈珊1，孙伯锋1，田兴德2 . 等离子低温射频消融联合下鼻甲骨折外移术治疗慢性肥厚性鼻炎的疗效观察[J]. 山东大学耳鼻喉眼学报, 2011, 25(2): 66-67.
[5]	陈敏，李娜. 变应性鼻炎和鼻息肉病患者血清蛋白质的差异表达[J]. 山东大学耳鼻喉眼学报, 2011, 25(2): 41-44.
[6]	李伟1，甘敏1，刘尚耀1，朱凤华1，杜明1，赵建东2. 共刺激分子OX40/OX40L在小鼠变应性鼻炎发病机制中的作用[J]. 山东大学耳鼻喉眼学报, 2011, 25(2): 45-47.
[7]	方建林，高兴强，赵德安. TLR₂、TLR₃和TLR₄在变应性鼻炎大鼠鼻黏膜组织中的表达[J]. 山东大学耳鼻喉眼学报, 2010, 24(4): 40-44.
[8]	孟庆翔, 谢景华, 苏芳, 王磊. 变应性鼻炎舌下含服粉尘螨滴剂免疫治疗早期鼻分泌物嗜酸细胞检测与临床分析[J]. 山东大学耳鼻喉眼学报, 2010, 24(3): 36-39.
[9]	曹忠良. 低温等离子在慢性鼻窦炎鼻内镜术后术腔清理中的疗效观察[J]. 山东大学耳鼻喉眼学报, 2010, 24(2): 41-42.
[10]	王新龙1，赵建东2. SOCS3及Ｅotaxin-2在变应性鼻炎中的表达及意义[J]. 山东大学耳鼻喉眼学报, 2010, 24(2): 26-29.
[11]	黄之勤. 鼻内镜下功能性重塑鼻腔结构治疗结构性鼻炎[J]. 山东大学耳鼻喉眼学报, 2010, 24(01): 34-36.
[12]	匡嘉丽吴军郭亮方向佳. 舌下含服脱敏治疗变应性鼻炎疗效观察[J]. 山东大学耳鼻喉眼学报, 2009, 23(4): 49-51.
[13]	李钦,马焱焱陈彦林杜英华张永东武彩霞. 转录因子GATA3对变应性鼻炎大鼠白细胞介素4和白细胞介素5的调控作用[J]. 山东大学耳鼻喉眼学报, 2008, 22(6): 520-522.
[14]	鲍爱春1，龚齐1，施葵1，孙臻峰2，董频2. 特应性因素与儿童变应性鼻炎及变应性鼻炎-哮喘综合征的关系[J]. 山东大学耳鼻喉眼学报, 2010, 24(6): 36-38.
[15]	孙岩, 宋西成, 张庆泉, 朱宇宏, 张华, 王强. 导航在鼻内镜下蝶窦手术的应用[J]. 山东大学耳鼻喉眼学报, 2009, 23(6): 13-.

多维度评价

Viewed

Full text

Abstract

Cited

Shared

Discussed