关键词: 气管切开；肺部感染；病原学

Abstract:

Objective   To study the etiological characteristic of patients with lung infection after tracheotomy. Methods   The  results of germiculture, the drug sensitivity from phlegm and the clinical data of 245 patients with lung infection after tracheotomy  from January 2008 to December 2010 were reviewed. Results   The incidence rate of iatrogenic infection of lung was 83.6%. 334 strains of pathogenic bacteria were isolated, of which 224 strains of Gram-negative bacilli accounted for 67.1%.The pathogens consisted of Pseudomonas aeruginosa (23.4%), Staphylococcus aureus(17.1%), Klebsiella pneumoniae(11.7%), Acinetobacter baumannii(10.5%), and Escherichia coli(9.6%). The drugs sensitive to Gram-negative bacilli were imipenem(73.7%) and piperacillin/tazobactam(61.1%), while the drugs sensitive to Grampositive cocci were vancomycin(100%) and nitrofurantion(92.9%). Drug resistance for ESBL(+)Gramnegative bacilli and MRSA obviously increased(P＜0.05). Conclusions   The main  pathogen of lung infection after tracheotomy in the hospital is Gram-negative bacilli. Antibiotic resistance of bacteria becomes severe. Phlegm cultivation and drug sensitivity testing should be actively developed in the clinic.

Key words: Tracheotomy; Iatrogenic  lung infection; Etiology