扁桃体切除术对变应性鼻炎合并支气管哮喘的影响

doi:10.6040/j.issn.1673-3770.0.2014.414

摘要/Abstract

摘要： 目的探讨变应性鼻炎行扁桃体切除后患者并发支气管哮喘的情况。方法将解放军第401医院北院耳鼻咽喉头颈外科1990年至2000年有详细资料的变应性鼻炎患者分为扁桃体切除组和非扁桃体切除组, 采用问卷的方式调查变应性鼻炎的程度、并发支气管哮喘的首发年龄、支气管哮喘的发病程度及自行用药的控制程度等。结果共调查变应性鼻炎患者1 249例, 其中扁桃体切除组128例, 46.88%的变应性鼻炎为轻度, 哮喘发生率为32.03%, 首发年龄为(32.40±7.63)岁, 中重度哮喘发病率为43.90%, 哮喘患者自行用药控制率达82.93%;非扁桃体切除组1 121例, 18.20%的变应性鼻炎为轻度, 哮喘发生率为47.55%, 首发年龄为(19.88±6.39)岁, 中重度哮喘发病率为43.90%, 哮喘患者自行用药控制率达68.10%。两组差异有统计学意义(P均<0.05 )。结论扁桃体切除术对变应性鼻炎并发支气管哮喘有一定的治疗作用。

关键词: 变应性鼻炎, 支气管哮喘, 扁桃体, 免疫反应

Abstract: Objective To explore the effect of tonsillectomy on patients with allergic rhinitis complicated with asthma. Methods A survey about allergic rhinitis severity, asthma starting age, disease severity and the medication control by patients themselves who were treated in the department of otorhinolaryngology, the 401 st hospital of PLA from 1990 to 2000 was carried out. Results A total of 1 249 allergic rhinitis patients completed the survey. The patients were divided into two groups: the tonsillectomy group(n=128) and the non-tonsillectomy group(n=1 121). Of the tonsillectomy group, the longitudinal allergic rhinitis rate was 46.88%, coucurrent asthma rate was 32.03%, asthma starting age was (32.4±7.63) years, moderate incidence rate of asthma was 43.9% and remission rate of asthma with drugs was 82.93%. Of the non-tonsillectomy group, the longitudinal allergic rhinitisrate was 18.20%, coucurrent asthma rate was 47.55%, asthma starting age was (19.88±6.39) years, moderate incidence rate of asthma was 43.90% and remission rate of asthma with drugs was 68.10%.The difference was statistically significant between the two groups(all P<0.05). Conclusion The tonsillectomy has a therapeutic effect on allergic rhinitis complicated with asthma.

Key words: Immune response, Allergic rhinitis, Asthma, Tonsil

中图分类号:

R765.21

王贵锋, 方文豪, 潘金斌, 魏茂彬, 王晓杰, 李云霞. 扁桃体切除术对变应性鼻炎合并支气管哮喘的影响[J]. 山东大学耳鼻喉眼学报, 2015, 29(4): 42-44.

WANG Guifeng, FANG Wenhao, PAN Jinbin, WEI Maobin, WANG Xiaojie, LI Yunxia. Evidences from clinical epidemiological survey for allergic rhinitis patients complicated by bronchial asthma after tonsillectomy.[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(4): 42-44.

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