山东大学耳鼻喉眼学报 ›› 2016, Vol. 30 ›› Issue (5): 98-100.doi: 10.6040/j.issn.1673-3770.0.2015.426

• 论著 • 上一篇    下一篇

CO2激光治疗声门型喉癌远期疗效分析

马玲国,郑朝攀,周敬淳,张博,龚桃根,张云静   

  1. 深圳市人民医院/暨南大学第二附属医院耳鼻咽喉头颈外科, 广东 深圳 518020
  • 收稿日期:2015-10-15 出版日期:2016-10-20 发布日期:2016-10-20
  • 作者简介:马玲国. E-mail:ljymax@163.com

Long-term curative effect of CO2 laser surgery for glottic laryngeal carcinoma.

MA Lingguo, ZHENG Chaopan, ZHOU Jingchun, ZHANG Bo, GONG Taogen, ZHANG Yunjing   

  1. Department of Otolaryngology &Head and Neck Surgery, Shenzhen Peoples Hospital / Second Clinical College of Jinan University, Shenzhen 518020, Guangdong, China
  • Received:2015-10-15 Online:2016-10-20 Published:2016-10-20

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摘要： 目的 探讨显微支撑喉镜下CO2激光治疗声门型喉癌的远期治疗效果。 方法 对声门型喉癌患者106例,采用显微支撑喉镜下CO2激光治疗,回顾性分析病历资料。其中TisN0M0 4例、T1aN0M0 62例、T1bN0M0 16例、T2N0M0 22例、T3N0M0 2例。 结果 106例患者手术顺利,无严重并发症发生。术后死于复发或颈部转移4例,死于意外4例,死于远处转移2例,失访4例,术后局部复发者再次手术后至今良好2例。目前92例仍存活,无肿瘤复发,生活质量良好。3年、5年和10年生存率分别为98.7%、95.2%和89.0%,总局部复发率为5.7%。 结论 显微支撑喉镜下CO2激光手术是治疗Tis、T1a声门型喉癌的首选方法,手术创伤小,术后恢复快,喉功能保全好,远期生存率高;该手术对于经过精心选择的声门型T1b和T2、T3喉癌也有较好的临床疗效。

关键词: 喉肿瘤, 声门型喉癌, 支撑喉镜, CO2激光, 鳞状细胞癌

Abstract: Objective To evaluate the long-term curative effect of CO2 laser surgery for glottic laryngeal carcinoma under microscopic suspension laryngoscope. Methods Clinical data of 106 cases of glottic laryngeal carcinoma were retrospectively analyzed, including 4 cases of TisN0M0, 62 cases of T1aN0M0, 16 cases of T1bN0M0, 22 cases of T2N0M0, and 2 cases of T3N0M0. All cases were treated with microscopic suspension laryngoscope CO2 laser surgery during 2004 and 2015. Results All operations were successful without serious complications. Of all 106 cases, 4 died of recurrence, 4 died of accidents, 2 died of distant metastases, 4 failed to be followed up, and 2 received a second operation due to recurrence and survived well. A total 92 patients were still alive without recurrence, with good quality of life. The 3, 5 and 10-year survival rate were respectively 98.7%, 95.2% and 89.0%. The local recurrence rate was 5.7%. Conclusion Microscopic suspension laryngoscope CO2 laser surgery is the preferred method for glottic laryngeal carcinoma Tis and T1a, which produces few surgical trauma, fast postoperative recovery, good laryngeal function preservation and high long-term survival rate. This operation method also has good clinical effect for selected cases of glottic laryngeal carcinoma T1b, T2 and T3.

Key words: Larynx neoplasm, Glottic cancer, Squamous-cell carcinoma, CO2 laser, Suspension laryngoscope

中图分类号: 

  • R739.65
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