山东大学耳鼻喉眼学报 ›› 2017, Vol. 31 ›› Issue (2): 73-76.doi: 10.6040/j.issn.1673-3770.0.2016.504

• 论著 • 上一篇    下一篇

糠酸莫米松鼻喷剂联合玉屏风颗粒可提高儿童腺样体肥大疗效

刘洁1,施陈燕2,张治军2   

  1. 1.上海市浦东新区潍坊社区卫生服务中心五官科, 上海 200122;
    2.上海中医药大学附属曙光医院耳鼻咽喉科, 上海 201203
  • 收稿日期:2016-11-30 出版日期:2017-04-16 发布日期:2017-04-16
  • 通讯作者: 张治军. E-mail:zjzhang2007@sina.com

Efficacy of mometasone furoate and Yupingfeng particles for adenoid hypertrophy in children.

  1. 1. Weifang Community Health Service Center, Pudong New District, Shanghai 200122, China;2. Department of Otolaryngology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • Received:2016-11-30 Online:2017-04-16 Published:2017-04-16

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摘要： 目的 探讨糠酸莫米松鼻喷剂联合玉屏风颗粒治疗儿童腺样体肥大的疗效。 方法 采用前瞻性随机对照研究,对90例4~10岁腺样体肥大儿童单用糠酸莫米松鼻喷剂或联合玉屏风颗粒口服治疗8周,对比治疗前后患儿临床症状积分,内镜下观察腺样体变化,记录上呼吸道感染次数。 结果 对照组(鼻喷激素)临床症状总积分减少19.5%,鼻咽阻塞程度从82.2%下降到73.6%(P<0.01),上呼吸道感染次数大于1次者占44.19%;试验组(联合用药)临床症状总积分减少31.7%,鼻咽阻塞程度从85.4%下降到71.4%(P<0.01),上呼吸道感染次数>1次者占16.67%。 结论 糠酸莫米松鼻喷剂治疗儿童腺样体肥大有效,联合玉屏风颗粒可进一步提高疗效,并可减少儿童上呼吸道感染的发生率。

关键词: 糠酸莫米松, 治疗结果, 腺样体肥大, 玉屏风颗粒

Abstract: Objective To explore the efficacy of Mometasone furoate and Yupingfeng particles in adenoid hypertrophy in children. Methods A total of 90 children aged 4-10 years completed 8 weeks treatment were enrolled in a prospective and randomized controlled study. The symptoms and degree of obstruction were evaluated by nasopharyngoscopy conducted pre-treatment and 8weeks post-treatment. Subjects received Mometasone furoate nasal spray alone at a daily dose of 200 μg or combination with Yupingfeng particles by a dose of 5 g twice a day for 8 weeks. Actual data were compared between the two groups. Results With Mometasone treatment, there was an 19.5 percent reduction in total clinical symptom score, and the degree of obstruction dropped from 82.2 to 73.6 percent(P<0.01). With Mometasone and Yupingfeng particles treatment, there was a 31.7 percent reduction in total clinical symptom score, and the degree of obstruction dropped from 85.4 to 71.4 percent(P<0.01). A statistically significant incidence of upper respiratory tract infection was seen in patients treated with Mometasone furoate nasal spray and Yupingfeng particles(16.7%)as compared with Mometasone alone(44.2%). Conclusion Mometasone furoate appears to be effective in treating children with adenoid hypertrophy. In combination with Yupingfeng particles, it can reduce the incidence of upper respiratory tract infection.

Key words: Yupingfeng particles, Adenoid hypertrophy, Mometasone furoate, Treatment outcome

中图分类号: 

  • R766.7
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