山东大学耳鼻喉眼学报 ›› 2018, Vol. 32 ›› Issue (5): 110-113.doi: 10.6040/j.issn.1673-3770.0.2018.034

• ·综述· • 上一篇    下一篇

甲状腺相关性眼病的诊断及治疗进展

朱明娟1,邢凯2,亢泽峰3,刘健3   

  1. 1.青海省中医院眼科, 青海 西宁 810000;
    2.北京市昌平区中医医院眼科, 北京 102200;
    3.中国中医科学院眼科医院, 北京 100040
  • 收稿日期:2018-01-15 出版日期:2018-09-20 发布日期:2018-09-20
  • 通讯作者: 邢凯. E-mail:cxingbkail@163.com

Diagnosis and treatment of thyroid-associated ophthalmopathy

ZHU Mingjuan1, XING Kai2, KANG Zefeng3, LIU Jian3   

  1. Changping District Hospital of Traditional Chinese Medicine, Beijing 102200, China;3. Eye Hospital of Chinese Academy of Traditional Chinese Medicine, Beijing 100040, China
  • Received:2018-01-15 Online:2018-09-20 Published:2018-09-20

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摘要： 甲状腺相关性眼病是一种与甲状腺功能异常相关的器官特异性自身免疫性疾病,该病最常见的是腺外器官受累,从而影响患者外观;重者可以导致复视、视力下降甚至失明,然其发病机制尚不完全清楚,目前临床上的治疗并不能达到100%满意。且临床上治疗方法有多种。实验室检查其主要的病理改变是眼睛的软组织和眼外肌的一些免疫炎性反应,但是确切的发病病理生化等机制尚不清楚。临床上诊疗难度大,就本病在临床诊断及治疗的最新研究进展进行综述。

关键词: 甲状腺相关性眼病, 研究进展, 临床诊断

Abstract: Thyroid-related ophthalmopathy is an organ-specific autoimmune disease associated with abnormal thyroid function. The extra-glandular ocular involvement affects the appearance of the patient; severe cases can present with diplopia, decreased vision, or even blindness. The pathogenesis is not yet fully understood, and the current clinical therapeutic approaches cannot cure or provide relief to all patients. Moreover, there are many clinical treatment methods. Histopathological examination of the ocular soft tissue and extra-ocular muscles shows some immune inflammatory response, but the exact pathogenesis of this disease is not clear. This article reviews the latest research on the clinical diagnosis and treatment of thyroid-related ophthalmopathy.

Key words: Research progress, Thyroid-associated ophthalmopathy, Clinical diagnosis

中图分类号: 

  • R777.1
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