山东大学耳鼻喉眼学报 ›› 2020, Vol. 34 ›› Issue (4): 5-10.doi: 10.6040/j.issn.1673-3770.1.2020.048
• 眼缺血综合征多学科精准诊疗 专家笔谈 • 上一篇 下一篇
杨明综述魏文斌审校
Central retinal artery occlusion(CRAO)is the most common cause of acute vision loss. Thrombolysis is a more radical treatment than conservative treatment, including arterial thrombolysis and intravenous thrombolysis, as well as the combination therapy of thrombolysis and other therapies. Thrombolysis treatment can improve the visual acuity of CRAO patients, but because of its lack of randomized controlled trials, further clinical studies are needed to determine their efficacy and safety. Our review summarized the application progress of thrombolysis in recent ten years, further evaluated its safety and effectiveness, and provided an evidence for clinical application.
摘要: 视网膜动脉阻塞是引起急性视力下降的眼科常见疾病, 溶栓治疗属于相对于保守治疗外较激进的治疗方法, 包括动脉溶栓和静脉溶栓, 以及溶栓与其他疗法的联合治疗, 溶栓治疗虽能提高患者视力, 但是因为其并存的风险以及缺少大样本前瞻随机对照研究而一直不能为临床提供有力的证据, 综述近十年国内外关于溶栓治疗的研究进展, 进一步评估其安全性和有效性, 为临床应用提供理论依据。
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[1] | 陈曦,李珊珊,赵露,尤冉,王艳玲. 动脉溶栓治疗视网膜中央动脉阻塞Meta分析[J]. 山东大学耳鼻喉眼学报, 2020, 34(4): 28-34. |
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