山东大学耳鼻喉眼学报 ›› 2021, Vol. 35 ›› Issue (6): 83-88.doi: 10.6040/j.issn.1673-3770.0.2021.227

• • 上一篇    下一篇

鼻内镜下改良下鼻甲成形术与下鼻甲低温等离子消融加骨折外移术治疗重度慢性肥厚性鼻炎的临床对比研究

张旻, 刘永亮, 宋道亮, 韩学锋, 封新荣, 赵允沛   

  1. 淄博市中心医院 耳鼻咽喉科, 山东 淄博 255000
  • 发布日期:2021-12-10
  • 通讯作者: 刘永亮. E-mail:liu_yl@sina.cn
  • 基金资助:
    山东省自然科学基金(ZR2020MC062);淄博市重点研发计划公益类专项(2019gy010003)

A comparative study on the treatment of severe chronic hypertrophic rhinitis by modified inferior turbinate plasty under nasal endoscopy and low-temperature plasma ablation with fracture displacement of the inferior turbinate

ZHANG Min, LIU Yongliang, SONG Daoliang, HAN Xuefeng, FENG Xinrong, ZHAO Yunpei   

  1. Department of Otorhinolaryngology, Zibo Central Hospital, Zibo 255000, Shandong, China
  • Published:2021-12-10

摘要: 目的 将鼻内镜下改良下鼻甲成形术与下鼻甲低温等离子消融加骨折外移术治疗重度慢性肥厚性鼻炎(下鼻甲黏膜、骨膜及骨质均增生肥大、鼻甲形态异常、VAS评分重度)进行对比研究。 方法 回顾性分析124例重度慢性肥厚性鼻炎患者,按照手术方式分为A(64例)、B(60例)两组,A组采用改良下鼻甲成形术,B组采用下鼻甲低温等离子消融加骨折外移术。术前1周、术后6个月、术后12个月分别用VAS标准评分患者鼻腔症状。糖精试验评价术前1周及术后6个月两组患者鼻腔黏膜纤毛传送功能。术前1周及术后6个月测定鼻阻力,评定鼻塞改善情况。 结果 下鼻甲低温等离子消融加骨折外移术组术中出血、手术时间较改良下鼻甲成形组明显减少,且术后并发症较少;术后6个月两种患者鼻塞均有显著改善;两种手术方式对鼻腔黏膜纤毛功能均无明显影响。A组平均手术时间27.80 min、并发症发生率9.38%,B组平均手术时间19.10 min、并发症发生率6.67%。两组患者术后6个月VAS平均评分差异无统计学意义(P=0.12),术后12个月差异有统计学意义(P=0.03)。 结论 改良下鼻甲成形术与下鼻甲低温等离子消融加骨折外移术治疗重度慢性肥厚性鼻炎近期效果(6个月内)都良好,但远期效果(1年以上)改良下鼻甲成形术效果更好,因而建议对于重度慢性肥厚性鼻炎患者应因人而异精准诊疗。

关键词: 改良下鼻甲成形术, 低温等离子消融术, 骨折外移术, 鼻内镜, 重度慢性肥厚性鼻炎, 临床效果

Abstract: Objective To compare the clinical effect of modified inferior turbinate plasty under nasal endoscopy and low-temperature plasma ablation with fracture displacement of the inferior turbinate in the treatment of severe chronic hypertrophic rhinitis(hypertrophy of the inferior turbinate mucosa and periosteum, abnormal turbinate morphology, and severe VAS score). Methods A total of 124 patients with severe chronic hypertrophic rhinitis were retrospectively analyzed. Patients were randomly divided into two groups according to the surgical method used: 64 patients in group A were treated with modified inferior turbinate plasty, and 60 patients in group B were treated with low-temperature plasma ablation of the inferior turbinate plus external fracture removal. The VAS standard score was used to evaluate nasal symptoms 1 week before as well as 6 and 12 months after surgery. Saccharin test was used to evaluate the nasal mucociliary transport function of patients in both groups, 1 week before and 6 months after surgery. Nasal resistance was measured 1 week before and 6 months after surgery, and the improvement in nasal obstruction was evaluated. Results Intraoperative hemorrhage was reduced, operative time was shorter, and the complications rate was lower in group B compared with group A. Six months after the surgery, nasal congestion significantly improved in both groups. Nasal mucociliary function was not significantly affected by either surgical methods. The average operation times were 27.80 min and 19.10 min, and the complication rates were 9.38% and 6.67%, in groups A and B, respectively. Comparison of the average VAS score after surgery between the two groups showed no statistically significant difference at 6 months after surgery(P=0.12); however, a statistically significant difference was found at 12 months after surgery(P=0.03) Conclusion Both surgical methods, modified inferior turbinate plasty and low-temperature plasma ablation of the inferior turbinate combined with fracture displacement, had good short-term effects(6 months)in the treatment of severe chronic hypertrophic rhinitis; further, modified inferior turbinate plasty had better long-term effect(>1 year). Therefore, it is suggested that precise diagnosis should be made and treatment should be accordingly performed in different patients with severe chronic hypertrophic rhinitis.

Key words: Modified inferior turbinate plasty, Low temperature plasma ablation, Displacement of fracture, Nasal endoscopy, Severe chronic hypertrophic rhinitis, Clinical effect

中图分类号: 

  • R765.21
[1] 田勇泉.耳鼻咽喉头颈外科学[M]. 6版.北京: 人民卫生出版社, 2010: 58-61.
[2] 黄选兆, 汪吉宝. 实用耳鼻咽喉科学[M]. 北京: 人民卫生出版社, 2007: 109-112.
[3] Asai K, Haruna S, Otori N, et al. Saccharin test of maxillary sinus mucociliary function after endoscopic sinus surgery[J]. Laryngoscope, 2000, 110(1): 117-122. doi:10.1097/00005537-200001000-00021.
[4] Boatsman JE, Calhoun KH, Ryan MW. Relationship between rhinosinusitis symptoms and mucociliary clearance time[J]. Otolaryngol Head Neck Surg, 2006, 134(3): 491-493. doi:10.1016/j.otohns.2005.10.045.
[5] Cmejrek RC, Gutman MT, Torres AJ, et al. The effect of injection immunotherapy on mucociliary clearance in allergic patients[J]. Otolaryngol Head Neck Surg, 2005, 133(1): 9-15. doi:10.1016/j.otohns.2005.03.062.
[6] Lin HC, Lin PW, Su CY, et al. Radiofrequency for the treatment of allergic rhinitis refractory to medical therapy[J]. Laryngoscope, 2003, 113(4): 673-678. doi:10.1097/00005537-200304000-00017.
[7] 袁晓培, 马有祥, 邢志敏, 等. 鼻内镜下鼻腔成形术治疗结构性鼻炎[J]. 临床耳鼻咽喉头颈外科杂志, 2007,21(17): 782-785. doi: 10.3969/j.issn.1001-1781.2007.17.006. YUAN Xiaopei, MA Youxiang, XING Zhimin, et al. Endoscopic rhinoplasty of nasal cavity for treatment of structural rhinitis[J]. J Clin Otorhinolaryngol Head Neck Surg, 2007,21(17): 782-785. doi: 10.3969/j.issn.1001-1781.2007.17.006.
[8] 钱克坚. 鼻内镜下鼻甲黏膜下切除治疗慢性肥厚性鼻炎172例[J]. 中国耳鼻咽喉颅底外科杂志, 2011,17(3): 229,231. doi: CNKI:SUN:ZEBY.0.2011-03-024.
[9] Lenders H, Pirsig W. Diagnostic value of acoustic rhinometry: patients with allergic and vasomotor rhinitis compared with normal controls[J]. Rhinology, 1990, 28(1): 5-16. PMID: 2336526.
[10] 韩德民. 下鼻甲的结构、功能与症状[J]. 耳鼻咽喉头颈外科, 2003, 10(4): 195-196. doi:10.3969/j.issn.1672-7002.2003.04.001. HAN Demin. The construction, function and symptom of inferior turbinate[J]. Chin Arch Otolaryngol-Head Neck Surg, 2003, 10(4): 195-196. doi:10.3969/j.issn.1672-7002.2003.04.001.
[11] 许庚, 杨钦泰, 徐睿, 等. 对下鼻甲手术的评价[J]. 耳鼻咽喉头颈外科, 2003, 10(4): 197-198. doi:10.3969/j.issn.1672-7002.2003.04.002. XU Geng, YANG Qintai, XU Rui, et al. Comment of inferior turbinate surgery[J]. Chin Arch Otolaryngol- Head Neck Surg, 2003, 10(4): 197-198. doi:10.3969/j.issn.1672-7002.2003.04.002.
[12] Churchill SE, Shackelford LL, Georgi JN, et al. Morphological variation and airflow dynamics in the human nose[J]. Am J Hum Biol, 2004, 16(6): 625-638. doi:10.1002/ajhb.20074.
[13] Damm M, Eckel HE, Jungehülsing M, et al. Olfactory changes at threshold and suprathreshold levels following septoplasty with partial inferior turbinectomy[J]. Ann Otol Rhinol Laryngol, 2003, 112(1): 91-97. doi:10.1177/000348940311200117.
[14] 王琪, 付维. 下鼻甲肥大的诊断和治疗[J]. 中国医学文摘·耳鼻咽喉科学, 2006, 21(3): 163-166. doi:10.19617/j.issn1001-1307.2006.03.011.
[15] 葛文彤. 下鼻甲手术历史和现状[J]. 耳鼻咽喉头颈外科, 2003, 10(4): 203-207. doi:10.3969/j.issn.1672-7002.2003.04.005.
[16] 史广涛, 王梅英, 孙慧远. 不同方式下鼻甲手术治疗慢性鼻炎的疗效观察[J]. 中国耳鼻咽喉头颈外科, 2021,28(2): 116-117. doi:10.16066/j.1672-7002.2021.02.013.
[17] 宋西成, 陈秀梅. 功能性鼻内镜手术中下鼻甲的处理及应用[J]. 山东大学耳鼻喉眼学报, 2011,25(5): 41-45.
[18] 牛善利, 柴茂文, 李振秀. 鼻内镜下鼻甲成形术治疗慢性肥厚性鼻炎60例[J]. 山东大学耳鼻喉眼学报, 2006, 20(1): 16-18. doi:10.3969/j.issn.1673-3770.2006.01.005. NIU Shanli, CHAI Maowen, LI Zhenxiu. Endoscopic rhinoplasty of inferior turbinate in 60 patients with chronic hypertrophic rhinitis[J]. J Otolaryngol Ophthalmol Shandong Univ, 2006, 20(1): 16-18. doi:10.3969/j.issn.1673-3770.2006.01.005.
[19] 肖水芳, 张俊波. 进一步规范化推广等离子射频技术在耳鼻咽喉头颈外科中的应用[J]. 山东大学耳鼻喉眼学报, 2021,35(2): 1-8. doi: 10.6040/j.issn.1673-3770.1. XIAO Shuifang, ZHANG Junbo. Further standardized promotion of the application of radiofrequency coblation in otorhinolaryngology, head and neck surgery[J]. J Otolaryngol Ophthalmol Shandong Univ, 2021,35(2): 1-8. doi: 10.6040/j.issn.1673-3770.1.
[20] Elwany S, Gaimaee R, Fattah HA. Radiofrequency bipolar submucosal diathermy of the inferior turbinates[J]. Am J Rhinol, 1999, 13(2): 145-149. doi:10.2500/105065899782106715.
[21] Berger G, Ophir D, Pitaro K, et al. Histopathological changes after coblation inferior turbinate reduction[J]. Arch Otolaryngol Head Neck Surg, 2008, 134(8): 819-823. doi:10.1001/archotol.134.8.819.
[22] 胡洁, 邹坚定, 胡志孟, 等. 下鼻甲等离子消融的能量释放对鼻黏膜纤毛功能及组织病理改变的影响[J]. 中国眼耳鼻喉科杂志, 2011,11(3): 137-139,205. doi:10.14166/j.issn.1671-2420.2011.03.008. HU Jie, ZOU Jianding, HU Zhimeng, et al. Effect of coblation inferior turbinate reduction on nasal mucosa[J]. Chin J Ophthalmol Otorhinolaryngol, 2011,11(3): 137-139,205. doi:10.14166/j.issn.1671-2420.2011.03.008.
[23] Bäck LJ, Hytönen ML, Malmberg HO, et al. Submucosal bipolar radiofrequency thermal ablation of inferior turbinates: a long-term follow-up with subjective and objective assessment[J]. Laryngoscope, 2002, 112(10): 1806-1812. doi:10.1097/00005537-200210000-00019.
[24] Larrabee YC, Kacker A. Which inferior turbinate reduction technique best decreases nasal obstruction?[J]. Laryngoscope, 2014, 124(4): 814-815. doi:10.1002/lary.24182.
[1] 李定波,唐志元,邓智毅,曾宪海,张秋航,王再兴. 低温等离子射频消融术治疗药物性鼻炎27例[J]. 山东大学耳鼻喉眼学报, 2022, 36(5): 11-17.
[2] 资昊坤,肖旭平,李云秋. 口服糖皮质激素在慢性鼻窦炎伴鼻息肉围手术期的应用现状[J]. 山东大学耳鼻喉眼学报, 2022, 36(3): 98-103.
[3] 曹轩,肖旭平,李云秋. 透明质酸在慢性鼻窦炎中的研究进展[J]. 山东大学耳鼻喉眼学报, 2022, 36(3): 104-109.
[4] 秦铭,孙占伟,王卫卫,李世超,武天义,王广科. 咽喉反流症状或体征评分阳性的慢性鼻窦炎患者鼻内镜术后碱性等渗盐水冲洗的疗效观察[J]. 山东大学耳鼻喉眼学报, 2022, 36(3): 147-153.
[5] 陈世琴,卫平存,胡云龙,胡金旺. 糖皮质激素三种不同鼻用法对鼻内镜术后黏膜转归的影响[J]. 山东大学耳鼻喉眼学报, 2022, 36(3): 195-201.
[6] 陈坤,陆慧,黄琦,李磊,孟国珍,杨军,侯东明. 小儿先天性鼻腔鼻窦肿物的临床诊疗观察[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 81-85.
[7] 芦晓妍, 温树信. 先天性后鼻孔闭锁的治疗进展[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 138-142.
[8] 巴广益,茆松,孙汐文,唐如,李志鹏,林海,张维天. Voxel-man ENT手术模拟系统在鼻科技能教学中的应用[J]. 山东大学耳鼻喉眼学报, 2021, 35(5): 56-61.
[9] 孙笑晗,李娜,陈凯璇,陈敏,闫舒,车飞. ROE量表在外鼻畸形合并鼻中隔偏曲患者手术前后生存质量评估中的应用[J]. 山东大学耳鼻喉眼学报, 2021, 35(3): 87-91.
[10] 王胜国,陈志太,周本忠,李龙巧,史先萍,吴飞凤,张泽生. 鼻内镜下联合低温等离子刀切除鼻腔鼻窦内翻性乳头状瘤37例[J]. 山东大学耳鼻喉眼学报, 2021, 35(2): 67-70.
[11] 李威,张斌. 优化脉冲光联合睑板腺按摩治疗睑板腺功能障碍的临床效果观察[J]. 山东大学耳鼻喉眼学报, 2021, 35(2): 105-109.
[12] 王再兴,唐志元,赵海亮,刘智献,李定波,李胜,马世博,卢永田. 电磁导航引导筛窦球囊成形术精准治疗慢性筛窦炎10例[J]. 山东大学耳鼻喉眼学报, 2021, 35(1): 61-68.
[13] 张金庄,殷璞,刘宁,王江宇,贾云芬,丁元吉,吴垚. FESS术后加用香菊胶囊与康复新液治疗慢性鼻窦炎伴有鼻息肉的对比研究[J]. 山东大学耳鼻喉眼学报, 2021, 35(1): 69-76.
[14] 陈坤,李磊,孟国珍,杨军,侯东明. 婴幼儿先天性基底型脑膜脑膨出的诊断及鼻内镜手术治疗[J]. 山东大学耳鼻喉眼学报, 2021, 35(1): 77-81.
[15] 田天捷,张自雄,杨飞,周意. 缝合腭弓对扁桃体术后出血影响的临床研究[J]. 山东大学耳鼻喉眼学报, 2021, 35(1): 82-85.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] 张晗,黄一飞 . 抗角膜移植排斥的研究进展[J]. 山东大学耳鼻喉眼学报, 2006, 20(1): 84 -87 .
[2] 牛善利,柴茂文,李振秀 . 鼻内镜下鼻甲成形术治疗慢性肥厚性鼻炎60例[J]. 山东大学耳鼻喉眼学报, 2006, 20(1): 16 -18 .
[3] 孟庆国,卢永田,范献良 . 杀伤细胞免疫球蛋白样受体基因多态性与鼻咽癌的关联性[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 196 -199 .
[4] 马玉起,孔祥春 . 先天性双侧下唇窦道1例[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 199 -199 .
[5] 万俐佳,鲁海涛,姜义道,刘 辉,李 琴,佘腊枝 . 改良腭咽成形术治疗阻塞性睡眠呼吸暂停综合征41例[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 204 -205 .
[6] 于青青 ,王跃建 . 硬质耳内镜的临床应用进展[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 222 -224 .
[7] 吉晓滨,邓家德,臧林泉,王 磊,谢 军 . 豚鼠变应性鼻炎模型血清组胺的测定[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 228 -230 .
[8] 向登,卢永田,孙焕吉 . 鼻内镜下修补脑脊液鼻漏19例并文献复习[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 234 -236 .
[9] 邱恩惠,李志春,方文旭 . 嗅觉障碍的中西医治疗[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 253 -257 .
[10] 殷国华,钟 笑 . 激光减容术治疗舌扁桃体肥大的远期疗效[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 280 -282 .