山东大学耳鼻喉眼学报 ›› 2016, Vol. 30 ›› Issue (3): 29-31.doi: 10.6040/j.issn.1673-3770.0.2015.389

• 论著 • 上一篇    下一篇

咽异物感伴有咽喉反流患者抗反流治疗的临床观察

周锋,王兴君,赵军,章少彬   

  1. 广州市第十二人民医院耳鼻咽喉头颈外科, 广东 广州 510620
  • 收稿日期:2015-09-11 出版日期:2016-06-16 发布日期:2016-06-16
  • 作者简介:周锋. E-mail:z63f@163.com

Clinical observation of anti-reflux treatment in patients with pharyngealforeign body sensation complicated with laryngopharyngeal reflux

ZHOU Feng, WANG Xingjun, ZHAO Jun, ZHANG Shaobin   

  1. Department of Otolaryngology &Head and Neck Surgery, The 12th Hospital of Guangzhou City, Guangzhou 510620, Guangdong, China
  • Received:2015-09-11 Online:2016-06-16 Published:2016-06-16

摘要: 目的 观察抗反流治疗对咽异物感伴有咽喉反流的临床疗效。 方法 将门诊以咽异物感自评超过3分,患病1个月以上的患者,进行反流症状指数量表(RSI)及反流临床表现量表(RFS)评分,对RSI超过13分及RFS超过7分的患者进行抗反流治疗,以能持续治疗8周以上为有效观察对象,共104例。分析入组患者反流各症状发生率、反流临床表现各体征发生率,并进行疗效评定。 结果 104例咽异物感患者多有反流症状清嗓动作(92/104,88.46%),主要反流体征为后连合肥厚(97/104,93.27%),红斑/充血(89/104,85.57%),喉内黏稠分泌物(87/104,83.65%),喉室阻塞(73/104,70.19%)等,经抗反流治疗,有效61例,有效率为58.65%;RSI治疗前后比较,差异有统计学意义(t=1.975,P<0.05);RFS治疗前后比较,差异无统计学意义(t=1.258,P>0.05)。 结论 咽异物感伴反流症状的患者,通过反流治疗是有效的。对于有咽异物感的患者,经过长期治疗效果不明显,应考虑是否有咽喉反流的可能。

关键词: 反流临床表现评分, 咽异物感, 反流症状指数, 咽喉反流

Abstract: Objective To observe the clinical efficacy of anti-refleux therapy in patients with pharyngealforeign body sensation complicated with laryngopharyngeal reflux. Methods A total of 104 patients were selected as study subjects, who had self-rating foreign-body sensation score>3 points, disease course≥1 months, and received continuous anti-reflux treatment for more than 8 weeks due to reflux symptom index(RSI)>13 points and reflux clinical presentation syndrome(RFS)>7 points after scoring. The rates of all reflux syndromes and signs of reflux clinical symptoms were analyzed, and clinical efficacy was evaluated. Results Of the 104 patients, most had reflux symptom hawking behavior(92/104,88.46%), with primary reflux signs being posterior commissurehypertrophy(97/104,93.27%), Erythema/congestion(89/104,85.57%), intra-throat sticky secretions(87/104,83.65%), ventriculuslaryngis obstruction(73/104,70.19%)and so on. After anti-reflux treatment, 61 were effective, with effective rate of 58.65%. Compared with treatment before, there was significant difference in RSI(t=1.975,P<0.05)but no significant difference was observed in RFS (t=1.258,P>0.05)after treatment. Conclusion Anti-reflux treatment is effective to patients with pharyngealforeign body sensation complicated with laryngopharyngeal reflux. As to patients with pharyngealforeign body sensation, laryngopharyngeal reflux should be considered if long-term treatment shows no significant efficacy.

Key words: Laryngopharyngeal reflux, Pharyngeal foreign body sensation, Reflux symptom index, Reflux clinical presentation syndrome

中图分类号: 

  • R766.1
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