山东大学耳鼻喉眼学报 ›› 2016, Vol. 30 ›› Issue (5): 1-4.doi: 10.6040/j.issn.1673-3770.0.2016.404

• 述评 •    下一篇

肥胖与阻塞性睡眠呼吸暂停

李延忠   

  1. 山东大学 齐鲁医院耳鼻咽喉头颈外科/卫生部耳鼻喉科学重点实验室, 山东 济南 250012
  • 收稿日期:2016-09-19 出版日期:2016-10-20 发布日期:2016-10-20
  • 通讯作者: 李延忠. E-mail:liyanzhong@sdu.edu.cn

Obesity and obstructive sleep apnea.

LI Yanzhong   

  1. Department of Otolaryngology &Head and Neck Surgery, Qilu Hospital of Shandong University / Key Laboratory of Otolaryngology of Health Ministry, Shandong University, Jinan 250012, Shandong, China
  • Received:2016-09-19 Online:2016-10-20 Published:2016-10-20

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摘要： 肥胖与OSA之间的关系是睡眠呼吸疾病领域一个新的热点,目前尚不清楚两者是因果关系还是伴随关系。肥胖胜过其他颅面畸形诱发阻塞性睡眠呼吸暂停(OSA),OSA 的频率与严重程度与体质量指数和肥胖相关,现就OSA与脂质代谢紊乱、脂肪肝、代谢性炎症、氧化应激四个方面的关系做一述评。

关键词: 氧化应激, 脂质代谢紊乱, 睡眠呼吸暂停,阻塞性, 脂肪肝, 代谢性炎症, 肥胖

Abstract: The relationship between obesity and obstructive sleep apnea-hypopnea syndrome(OSAHS)has become a new hot spot in the research of sleep-disordered breathing. Whether there is a cause-and-effect or accompanying relationship between them is not yet clear. Compared with craniofacial malformations, obesity is more likely to induce obstructive sleep apnea syndrome(OSA). The frequency and severity of OSA are related to BMI and obesity. This paper discusses the relationship from four aspects: lipid metabolism disorder, fatty liver, metabolic inflammation, and oxidative stress.

Key words: Obesity, Fatty liver, Metabolic inflammation, Obstructive sleep apnea hypopnea syndrome, Disorder of lipid metabolism, Oxidative stress

中图分类号: 

  • R766.7
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