碳酸氢钠联合氟康唑注射液治疗真菌性外耳道炎35例

doi:10.6040/j.issn.1673-3770.0.2016.178

山东大学耳鼻喉眼学报 ›› 2016, Vol. 30 ›› Issue (6): 22-23.doi: 10.6040/j.issn.1673-3770.0.2016.178

碳酸氢钠联合氟康唑注射液治疗真菌性外耳道炎35例

沈莉

溧阳市中医医院耳鼻喉科, 江苏溧阳 213300

收稿日期:2016-04-21 出版日期:2016-12-16 发布日期:2016-12-16
作者简介:沈莉. E-mail:shenli_pig@sohu.com

Efficacy of sodium bicarbonate and fluconazole in the treatment of fungal otitis externa.

SHEN Li

Department of Otolaryngology, Liyang Traditional Chinese Medicine Hospital, Liyang 213300, Jiangsu, China

Received:2016-04-21 Online:2016-12-16 Published:2016-12-16

摘要/Abstract

摘要： 目的探讨碳酸氢钠联合氟康唑注射液治疗真菌性外耳道炎的疗效。方法使用随机平行对照方法,将真菌性外耳道炎患者105例,分为治疗组(碳酸氢钠联合氟康唑注射液耳浴);对照一组(氟康唑注射液耳浴);对照二组(2%水杨酸酒精耳浴),每组35例,连用10 d为一疗程,随访一年观察疗效。结果 3个组的总有效率分别为91.43%、85.71%、77.14%,治疗组疗效优于2个对照组(P<0.05)。结论碳酸氢钠联合氟康唑注射液治疗真菌性外耳道炎的疗效优于单独采用氟康唑注射液或2%水杨酸酒精。

关键词: 碳酸氢钠, 氟康唑, 水杨酸, 真菌性外耳道炎

Abstract: Objective To explore the clinical efficacy of sodium bicarbonate combined with fluconazole in the treatment of fungal otitis externa. Methods Using random parallel control method, 105 patients with fungal otitis externa were divided into three groups: the treatment group(ear bath with sodium bicarbonate plus fluconazole injection); control group 1(ear bath with fluconazole injection); control group 2(ear bath with 2% salicylic acid alcohol), with 35 cases in each group. The treatment lasted for 10 days. The patients were followed up for one year to observe the curative effect. Results The total effective rate of the 3 groups were 91.43%, 85.71%, and 77.14%. The efficacy of the treatment group was better than that of the control groups(P<0.05). Conclusion Sodium bicarbonate combined with fluconazole is better than 2% salicylic acid alcohol or fluconazole alone in the treatment of fungal otitis externa.

Key words: Fluconazole, Salicylic acid, Sodium bicarbonate, Fungal otitis externa

中图分类号:

R763

沈莉. 碳酸氢钠联合氟康唑注射液治疗真菌性外耳道炎35例[J]. 山东大学耳鼻喉眼学报, 2016, 30(6): 22-23.

SHEN Li. Efficacy of sodium bicarbonate and fluconazole in the treatment of fungal otitis externa.[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(6): 22-23.

参考文献

[1] 尹世芬. 外耳道真菌病三种抗真菌药物治疗的效果观察[J]. 齐齐哈尔医学院学报, 2012, 33(8):1005-1006. YIN Shifen. Observation on clinical application of three kinds of anti-fungis on fungi disease of outer ears[J]. J Qiqihar Med Univ, 2012, 33(8):1005-1006.
[2] Jia X, Liang Q, Chi F, et al. Otomycosis in Shanghai: aetiology, clinical features and therapy[J]. Mycoses, 2012, 55(5):404-409.
[3] 吴小飞. 氟康唑氯化钠注射液外用于外耳道治疗真菌性外耳道炎的可行性及安全性[J]. 社区医学杂志, 2012, 10(22):6-7. WU Xiaofei. Feasibility and safety of external application of fluconazole and sodium chloride injection for fungal otitis externa[J]. J Community Med, 2012, 10(22):6-7.
[4] 舒畅, 吴庆莲, 吴雯. 氟康唑注射液灌洗法治疗真菌性外耳道炎73例[J]. 中国伤残医学, 2011, 19(9):57. SHU Chang, WU Qinglian, WU Wen. Fluconazole injection irrigation treatment for 73 cases of fungal otitis externa[J]. Chin J Traumaz Disability Med, 2011, 19(9):57.
[5] 白素萍. 碱性溶液耳浴加微波照射治疗真菌性外耳道炎的观察与护理[J]. 全科护理, 2010, 8(5):377-378. BAI Suping. Observation and nursing care of patients with external auditory canal otomycosis treated with alkaline solution ear bath and microwave irradiation[J]. Chin General Nursing, 2010, 8(5):377-378.

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碳酸氢钠联合氟康唑注射液治疗真菌性外耳道炎35例

Efficacy of sodium bicarbonate and fluconazole in the treatment of fungal otitis externa.

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