术后第一天甲状旁腺激素水平对甲状腺全切术后甲状旁腺功能恢复的预测价值

doi:10.6040/j.issn.1673-3770.0.2017.336

山东大学耳鼻喉眼学报 ›› 2017, Vol. 31 ›› Issue (5): 89-91.doi: 10.6040/j.issn.1673-3770.0.2017.336

术后第一天甲状旁腺激素水平对甲状腺全切术后甲状旁腺功能恢复的预测价值

黄天桥,姜晓丹,车飞,黄沂传,孙彦,张念凯,李慎玲,陈志俊,李薇

青岛大学附属医院耳鼻咽喉头颈外科, 山东青岛 266003

收稿日期:2017-08-08 出版日期:2017-10-16 发布日期:2017-10-16
通讯作者: 李薇. E-mail:liweishang@126.com

Value of parathyroid hormone levels on postoperative day 1 for predicting parathyroid function after total thyroidectomy.

HUANG Tianqiao, JIANG Xiaodan, CHE Fei, HUANG Yichuan, SUN Yan, ZHANG Niankai, LI Shenling, CHEN Zhijun, LI Wei

Department of Otorhinolaryngology Head and Neck Surgery, the Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong, China

Received:2017-08-08 Online:2017-10-16 Published:2017-10-16

摘要/Abstract

摘要： 目的通过追踪测定甲状腺全切术后患者第1天、第3天及第30天的甲状旁腺激素(PTH)水平,判断术后第1天PTH水平能否预测甲状腺全切术后甲状旁腺功能损伤的恢复,有助于判断及处理患者术后低钙血症。方法病例资料为2014年9月至2016年12月接受甲状腺全切术后的68例患者,测定术后第1天、第3天、第30天的PTH值并根据术后第1天PTH值将患者分为三组: PTH<5 pg/mL(A组), 5 pg/mL≤PTH<10 pg/mL(B组), PTH≥10 pg/mL(C组)。统计三组患者在术后第3天、第30天低甲状旁腺激素发生率。结果 PTH值越高,低甲状旁腺激素发生率越低,术后第3天,A组和C组、B组和C组比较差异有统计学意义;术后第30天,A组和C组差异有统计学意义,B组和C组差异无统计学意义。结论当术后第1天PTH<5 pg/mL 时,30 d内较难恢复到正常水平,容易出现低钙血症。当PTH≥10 pg/mL,30 d内较容易恢复到正常水平。

关键词: 甲状腺全切术, 甲状旁腺素, 低钙血症

Abstract: Objective To explore whether parathyroid hormone(PTH)levels on postoperative day 1 can predict the recovery of parathyroid function by determining the PTH levels on postoperative days 1, 3, and 30 in patients who underwent total thyroidectomy. Methods The clinical data of 68 patients treated with total thyroidectomy between September 2014 and December 2016 were retrospectively analyzed. The PTH levels were determined on postoperative days 1, 3, and 30. The patients were then divided into three groups on the basis of PTH levels on postoperative day 1: Group A, PTH<5 pg/mL; Group B, 5 pg/mL≤PTH<10 pg/mL; and Group C, PTH≥10 pg/mL. Results Higher PTH levels on postoperative day 1 correlated with lower incidence rates of low parathyroid function. On postoperative day 3, there was a difference between Groups A and C, and Groups B and C. Again, on postoperative day 30, there was a difference between Groups B and C. Conclusion If PTH levels on postoperative day 1 are less than 5 pg/mL, it is difficult to recover normal levels and hypocalcemia will occur within 30 days. However, if PTH levels on postoperative day 1 are ≥10 pg/mL, it is easier to recover normal levels.

Key words: Parathyroid hormone, Total thyroidectomy, Hypocalcemia

中图分类号:

R653

黄天桥,姜晓丹,车飞,黄沂传,孙彦,张念凯,李慎玲,陈志俊,李薇. 术后第一天甲状旁腺激素水平对甲状腺全切术后甲状旁腺功能恢复的预测价值[J]. 山东大学耳鼻喉眼学报, 2017, 31(5): 89-91.

HUANG Tianqiao, JIANG Xiaodan, CHE Fei, HUANG Yichuan, SUN Yan, ZHANG Niankai, LI Shenling, CHEN Zhijun, LI Wei. Value of parathyroid hormone levels on postoperative day 1 for predicting parathyroid function after total thyroidectomy.[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(5): 89-91.

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术后第一天甲状旁腺激素水平对甲状腺全切术后甲状旁腺功能恢复的预测价值

Value of parathyroid hormone levels on postoperative day 1 for predicting parathyroid function after total thyroidectomy.

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