山东大学耳鼻喉眼学报 ›› 2018, Vol. 32 ›› Issue (5): 50-52.doi: 10.6040/j.issn.1673-3770.0.2018.112

• ·论著· • 上一篇    下一篇

突发性聋30例精神心理状况分析

朱文燕1,金新1,佘万东2,马永驰1   

  1. 1.南京医科大学附属淮安第一医院, 江苏 淮安 223300;
    2.南京大学附属鼓楼医院, 江苏 南京 210008
  • 收稿日期:2018-03-02 出版日期:2018-09-20 发布日期:2018-09-20

Assessment of psychopathological characteristics in 30 patients with sudden sensorineural hearing loss

ZHU Wenyan1, JIN Xin1, SHE Wandong2, MA Yongchi1   

  1. Drum Tower Hospital Affiliated to Nanjing University, Nanjing 210008, Jiangsu, China
  • Received:2018-03-02 Online:2018-09-20 Published:2018-09-20

摘要: 目的 初步了解突发性聋患者的精神心理状况。 方法 对30例突发性聋患者(突聋组)及20例健康对照成人(对照组)进行90项症状自评量表(SCL-90)心理学测试及血浆中5-羟色胺(5-HT)检测。 结果 突聋组SCL-90总分为(121.69±22.53)分,总均分为(1.35±0.25)分,对照组SCL-90总分为(111.65±15.25)分,总均分为(1.23±0.25)分。突聋组SCL-90总分及总均分与对照组比较,P均>0.05。但突聋组躯体化、抑郁、偏执和其他(睡眠、饮食等)这四个因子分均高于对照组(P均<0.05)。突聋组5-HT含量较对照组降低(P<0.05),SCL-90评分与血浆5-HT水平呈负相关(r=-0.507, P=0.004)。 结论 突发性聋患者较正常人有轻度心理精神障碍倾向,存在明显抑郁、偏执及睡眠等障碍,且5-HT含量较正常人明显减少。

关键词: 突发性聋, 精神心理, 抑郁, 5-羟色胺, 90项症状自评量表

Abstract: Objective To investigate the psychopathological characteristics of patients with sudden sensorineural hearing loss(SSHL). Methods The Symptom Checklist-90(SCL-90)scores and plasma 5-hydroxytryptamine(5-HT)levels were determined in 30 patients with SSHL and 20 healthy adult controls. Results The total and average SCL-90 scores were 121.69±22.53 and 1.35±0.25, respectively, in the SSHL group, and 111.65±15.25 and 1.23±0.25 in the control group. There were no significant differences in total and average scores between the two groups(P>0.05). However, the SCL-90 scores for the four dimensions of somatization, depression, paranoia, and other(sleep, diet, etc.)were higher in the SSHL group than in the control group, and the difference was statistically significant(P< 0.05). The plasma 5-HT level in the SSHL group was significantly lower than in the normal control group(P<0.05)and the SCL-90 score was negatively correlated with the plasma 5-HT (r=-0.507, P=0.004). Conclusion Compared with healthy adults, patients with SSHL show a tendency toward mild psychopathology. Patients with SSHL have clear evidence of depression, paranoia, and sleep disorders, and significantly lower plasma 5-HT levels compared to healthy adults.

Key words: Depression, 5-hydroxytryptamine, Symptom Checklist-90, Sudden hearing loss, Psychopathological characteristics

中图分类号: 

  • R764.437
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