山东大学耳鼻喉眼学报 ›› 2020, Vol. 34 ›› Issue (4): 60-63.doi: 10.6040/j.issn.1673-3770.1.2020.056

• 眼缺血综合征多学科精准诊疗 临床研究 • 上一篇    下一篇

眼缺血综合征患者脉络膜厚度的分析

傅强,王红星   

  1. 傅强, 王红星北京市垂杨柳医院 眼科, 北京 100022
  • 收稿日期:2019-05-29 出版日期:2020-07-20 发布日期:2020-08-28

Analysis of choroidal thickness in patients with ocular ischemic syndromeFU Qiang, WANG Hongxing Department of Ophthalmology, Beijing Chuiyangliu Hospital, Beijing 100022, ChinaAbstract: Objective〓

Spectral-domain optical coherence tomography(SD-OCT)was used to measure and observe the characteristics of the subfoveal choroidal thickness(SFCT)in patients with ocular ischemic syndrome(OIS)as well as explore the indicators for early evaluation of OIS. MethodsThis was a retrospective case-control study. Forty-eight patients(48 eyes)were included between January 2017 and January 2020. The patients were divided into two groups: the OIS and the control groups, with each consisting of 24 patients(24 eyes). Their basic information, including age, gender, body mass index(BMI), and the history of diabetes, hypertension, and hyperlipidemia, was collected. SFCT was measured using SD-OCT in EDI mode. The basic data and SFCTs of the two groups were compared. ResultsThere were no significant differences between the ages, gender, BMIs, and the prevalence of diabetes, hypertension, and hyperlipidemia of the two groups(all P>0.05). The mean SFCT of the OIS group was 204.83±27.34 μm, and that of the control group was 226.58±33.49 μm. The differences between the two groups were statistically significant(t=2.464, P=0.018). ConclusionsSFCT was thinner in patients with OIS. SFCT can be used as an indicator for early assessment of OIS.   

  1. Key words:Ocular ischemic syndrome(OIS);
    Choroidal thickness;
    Spectral-domain optical coherence tomography(SD-OCT)眼缺血综合征［1］(ocular ischemic syndrome, OIS)由慢性严重的颈动脉阻塞或狭窄所致脑和眼的供血不足而产生一系列颅内缺血和眼部缺血的临床综合征。OIS可造成脑卒中［2］、心肌梗死［3］等致命性疾病的发生, 也可引起永久性视力损伤［4］。有研究表明［5］眼部缺血会先于脑血管病的发生。因此探索OIS患者眼部的评估指标对于预警致命性的心脑血管事件的发生有至关重要的意义。我们应用频域光学相干断层扫描仪(spectral-domain optical coherence tomography, SD-OCT)的增强深度成像(enhanced depth imaging, EDI)模式, 测量黄斑中心凹下脉络膜厚度(subfoveal choroidal thickness, SFCT), 旨在观察OIS患者SFCT的特征, 进一步探索早期评估OIS的指标。
  • Received:2019-05-29 Online:2020-07-20 Published:2020-08-28

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摘要： 目的 应用频域光学相干断层扫描仪(SD-OCT)测量眼缺血综合征(OIS)患者黄斑中心凹下脉络膜厚度(SFCT),观察OIS患者SFCT的特征,探索早期评估OIS的指标。 方法 为回顾性病例对照研究,共纳入2017年1月至2020年1月在北京市垂杨柳医院就诊患者48例(48眼),以是否确诊OIS将患者分为OIS组24例(24眼),对照组24例(24眼)。采集患者基线资料如年龄、性别、体质量指数(BMI)、糖尿病病史、高血压病史、高脂血症病史,应用SD-OCT的EDI模式测量SFCT,比较两组间的基线资料和SFCT的差异。 结果 OIS组和对照组患者在年龄、性别、BMI、糖尿病患病率、高血压患病率、高脂血症患病率方面相比,差异均无统计学意义(均P>0.05)。OIS组的平均SFCT为(204.83±27.34)μm,对照组的平均SFCT为(226.58±33.49)μm,两组的SFCT相比差异有统计学意义(t=2.464, P=0.018)。 结论 OIS患者的SFCT明显变薄,SFCT可作为早期评估OIS的指标。

关键词: 眼缺血综合征, 脉络膜厚度, 频域光学相干断层扫描

Abstract: Objective Spectral-domain optical coherence tomography(SD-OCT)was used to measure and observe the characteristics of the subfoveal choroidal thickness(SFCT)in patients with ocular ischemic syndrome(OIS)as well as explore the indicators for early evaluation of OIS. Methods This was a retrospective case-control study. Forty-eight patients(48 eyes)were included between January 2017 and January 2020. The patients were divided into two groups: the OIS and the control groups, with each consisting of 24 patients(24 eyes). Their basic information, including age, gender, body mass index(BMI), and the history of diabetes, hypertension, and hyperlipidemia, was collected. SFCT was measured using SD-OCT in EDI mode. The basic data and SFCTs of the two groups were compared. Results There were no significant differences between the ages, gender, BMIs, and the prevalence of diabetes, hypertension, and hyperlipidemia of the two groups(all P>0.05). The mean SFCT of the OIS group was 204.83±27.34 μm, and that of the control group was 226.58±33.49 μm. The differences between the two groups were statistically significant(t=2.464, P=0.018). Conclusions SFCT was thinner in patients with OIS. SFCT can be used as an indicator for early assessment of OIS.

Key words: Ocular ischemic syndrome(OIS), Choroidal thickness, Spectral-domain optical coherence tomography(SD-OCT)

中图分类号: 

  • R773.1
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