山东大学耳鼻喉眼学报 ›› 2020, Vol. 34 ›› Issue (5): 72-77.doi: 10.6040/j.issn.1673-3770.1.2020.069

• 临床研究 • 上一篇    下一篇

听力正常儿童骨导前庭诱发肌源性电位正常值的建立

沈佳丽, 孙夏雨, 陈向平, 杨军, 陈建勇, 汪玮, 张勤, 王璐, 马孝宝, 贺宽, 沈敏   

  1. 沈佳丽, 孙夏雨, 陈向平, 杨军, 陈建勇, 汪玮, 张勤, 王璐, 马孝宝, 贺宽, 沈敏上海交通大学医学院附属新华医院 耳鼻咽喉头颈外科/上海交通大学医学院耳科学研究所/上海市耳鼻疾病转化医学重点实验室, 上海 200092
  • 收稿日期:2020-07-15 发布日期:2020-11-17
  • 作者简介:沈佳丽、孙夏雨,共同第一作者
  • 基金资助:
    上海交通大学医工交叉重点项目(ZH2018ZDA11);上海交通大学医学院附属新华医院院级临床研究培育基金项目(17CSK03,18JXO04)

The establishment of a normal value of bone-conducted vestibular-evoked myogenic potential in normal-hearing children

  • Received:2020-07-15 Published:2020-11-17

摘要: 目的 记录听力正常儿童骨导前庭诱发肌源性电位(BC-VEMP)特征,为临床儿童前庭功能评估提供参考。 方法 选择31名(62耳)4~12岁听力正常儿童,按照年龄进行分组,4~5岁组11人(22耳),6~12岁组20人(40耳),行BC-VEMP测试。将60 dB nHL作为起始刺激强度,记录骨导刺激时颈性VEMP(cVEMP )、眼性VEMP(oVEMP)的N1潜伏期、P1潜伏期、N1-P1波间期、N1-P1波幅、波幅不对称比以及阈值。使用SPSS软件进行统计学分析。 结果 4~12岁听力正常儿童BC-VEMPs引出率为100%。4~5岁组与6~12岁组相比,BC-cVEMP的P1、N1潜伏期、P1-N1波间期、P1-N1波幅、阈值、波幅不对称比均无统计学差异(P>0.05)。两组间BC-oVEMP的N1、P1潜伏期、N1-P1波间期、N1-P1波幅、阈值、波幅不对称比均无统计学差异(P>0.05)。 结论 BC-VEMPs是一种可行的前庭功能辅助性检査手段,不同年龄段儿童BC-VEMPs正常值的建立,可为儿童前庭功能的评估提供参考。

关键词: 听力正常儿童, 骨导颈性前庭诱发肌源性诱发电位, 骨导眼性前庭诱发肌源性电位, 不同年龄段, 正常参考值

Abstract: Objective To record the bone-conducted vestibular-evoked myogenic potential(BC-VEMP)in order to provide a reference for the clinical evaluation of vestibular function in normal-hearing children. Methods Thirty-one normal-hearing children(62 ears)aged 4-12 years were selected to undergo BC-VEMP determination. These children were divided into two groups according to age. Those aged 4-5 years(11 children, 22 ears)belonged to one group while those aged 6-12 years(20 children, 40 ears)belonged to the other. A 60 dB nHL was used as the initial stimulus intensity by which the N1 latency, P1 latency, n1-p1 interval, n1-p1 amplitude, amplitude asymmetry ratio, and threshold of cervical VEMP(CVMP)and ocular VEMP(ocular VEMP)were recorded. The SPSS software was used for statistical analysis. Results There was no significant difference in P1, N1 latency, P1-N1 wave interval, P1-N1 amplitude, threshold, and amplitude asymmetry ratio of BC-oVEMP between the 4-5-year-old and the 6-12-year-old groups(P>0.05). There was no significant difference in N1, P1 latency, n1-p1 wave interval, n1-p1 amplitude, threshold, and amplitude asymmetry ratio of BC-VEMP between the two groups(P>0.05). Conclusion BC-VEMP is a feasible auxiliary examination of vestibular function. The establishment of normal values of BC-VEMP in different age groups can provide a reference for clinical evaluation of vestibular function in children.

Key words: Normal hearing Children, Bone-conducted cervical vestibular evoked myogenic potential, Bone-conductedBone conduction ocular vestibular myogenic evoked myogenic potential, Different age groups, Normal reference value

中图分类号: 

  • R764.43
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