前庭诱发肌源性电位检查的点评

doi:10.6040/j.issn.1673-3770.1.2020.081

摘要/Abstract

摘要： 借由气导声刺激或骨导振动刺激可成功诱发前庭诱发肌源性电位(vestibular-evoked myogenic potential, VEMP)。从颈部胸锁乳突肌表面记录得到的VEMP称为颈肌前庭诱发肌源性电位(cVEMP),从眼外肌表面记录得到的VEMP称为眼肌前庭诱发肌源性电位(oVEMP)。这两项新兴的耳神经科学功能检查开启了科学家探索耳石器官(球囊与椭圆囊)的纪元,分别用来检测“球囊-颈肌反射”和“椭圆囊-眼肌反射”神经通路。内耳功能检查序列,包括听力检查、cVEMP检查、oVEMP检查、温度试验检查等,可以对内耳终末器官诸如耳蜗、球囊、椭圆囊及半规管的功能进行全面检测,目前已经广泛应用于动物及人体。这一系列内耳功能检测项目将有助于描绘内耳终末器官受侵犯的范围、厘清过去医学上的盲点,进一步阐明内耳及中枢前庭系病变的机制。

关键词: 气导声刺激, 骨导振动刺激, 颈肌前庭诱发肌源性电位, 眼肌前庭诱发肌源性电位, 球囊-颈肌反射, 椭圆囊-眼肌反射, 内耳功能检查

Abstract: Stimulation via air-conducted sound or bone-conducted vibration enables recording of vestibular-evoked myogenic potential(VEMP)from cervical muscles(called cervical VEMP, cVEMP)and extraocular muscles(termed ocular VEMP, oVEMP). These two emerging tests expand the test battery available to clinicians for exploring dynamic otolithic function, and create a potential use for the sacculo-collic reflex and utriculo-ocular reflex, respectively. Coupled with audiometry and caloric test, the inner ear test battery is designed to assess the inner ear function including the cochlea, saccule, utricle and semicircular canals. Clinically, the inner ear test battery has been widely adopted in humans and experimental animals. It is believable that comprehensive assessment of the inner ear function via an inner ear test battery may stimulate to elucidate the mechanism of peripheral and central vestibular disorders.

Key words: Air-conducted sound, Bone-conducted vibration, Cervical vestibular-evoked myogenic potential, Ocular oVEMP, Sacculo-collic reflex, Utriculo-ocular reflex, Inner ear test battery

中图分类号:

R764.34

杨怡和. 前庭诱发肌源性电位检查的点评[J]. 山东大学耳鼻喉眼学报, 2020, 34(5): 113-117.

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