山东大学耳鼻喉眼学报 ›› 2010, Vol. 24 ›› Issue (2): 8-10.

• 论文 • 上一篇    下一篇

山东东部地区女性喉癌患者的临床特点

刘章,孙彦,华辉,陈志俊,李薇,孙文海   

  1. 青岛大学医学院附属医院耳鼻咽喉头颈外科, 山东 青岛 266003
  • 收稿日期:2010-03-01 修回日期:2010-04-06 出版日期:2010-04-16 发布日期:2010-04-16
  • 通讯作者: 孙彦(1962- ),男,主任医师,教授,硕士生导师,主要从事头颈部肿瘤和咽喉部疾病的研究。 Email:sunyanohns@yahoo.com.cn
  • 作者简介:刘章(1984- ),男,硕士研究生,主要从事头颈部肿瘤临床和基础方面研究。 Email:entliuzhang@yahoo.cn

Clinical features of laryngeal carcinoma in females in the east of Shandong Province

LIU Zhang, SUN Yan, HUA Hui, CHEN Zhijun, LI Wei, SUN Wenhai   

  1. Department of Otorhinolaryngology & Head and Neck Surgery, The Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, Shandong, China
  • Received:2010-03-01 Revised:2010-04-06 Online:2010-04-16 Published:2010-04-16

摘要:

目的  探讨山东东部地区女性喉癌患者的临床特点。 方法   对22例女性喉癌患者资料进行回顾性分析,其中声门上型8例,声门型13例,声门下型1例;按2002年AJCC标准进行分期:Ⅰ期10例,Ⅱ期2例,Ⅲ期4例,Ⅳ期6例。行喉部分切除术14例,喉全切除术6例,同时行颈清扫术10例,术后放疗10例。单纯放疗2例。生存率采用直接法计算。结果  行手术治疗的20例中,治疗后满3年者11例,失访2例,无瘤生存8例,3年直接生存率72.7%;治疗后满5年者6例,失访1例,无瘤生存5例,5年直接生存率83.3%;行单纯放射治疗的2例分别于治疗后9个月和1年死于复发。结论  女性喉癌发病率较低,声门上型喉癌构成比相对较高,部分女性喉癌患者与吸烟有关,女性喉癌患者的多原发癌值得重视

关键词: 喉肿瘤;癌,鳞状细胞;女性;外科手术;存活率

Abstract:

Objective  To investigate the clinical features of laryngeal carcinoma in females in the East of Shandong Province. Methods  Twenty-two female patients with laryngeal carcinoma were retrospectively analyzed, including 8 cases of supraglottic carcinoma, 13 cases of glottic carcinoma and 1 case of subglottic carcinoma. According to AJCC(2002), there were 10 cases in stageⅠ, 2 cases in stageⅡ,4 cases in stage Ⅲ, and 6 cases in stage Ⅳ. Partial laryngectomy was performed in 14 patients and total laryngectomy in 6 patients. 10 patients underwent neck dissection synchronously. Radiotherapy was performed in 10 patients after surgery. And 2 patients only received radiotherapy. The direct method was used to calculate the survival rate. Results  Among the 20 patients who received surgery, 11 were followed up for more than 3 years: 2 were missed and 8 were disease-free survival. The 3-year survival rate was 72.7%. Only 6 patients were followed up for more than 5 years: 1 was missed and 5 were disease-free survived. The 5-year survival rate was 83.3%. The two patients who only received radiotherapy died because of the relapse in 9 months and 1 year after treatment respectively. Conclusion  Laryngeal carcinoma in females has a low incidence. Supraglottic carcinoma is relatively common in female patients. Smoking is an important factor in some females. Multiple primary carcinomas should be focused on in females.

Key words: Laryngeal neoplasms; Carcinoma, Squamous cell; Female; Surgery; Survival rate

中图分类号: 

  • R739.6
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