Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2021, Vol. 35 ›› Issue (4): 8-11.doi: 10.6040/j.issn.1673-3770.0.2020.421

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Comparative study of holmium and CO2 laser surgeries for early glottic carcinoma

CHEN Guoping, FU Minyi, YE Fei, XU Jianhui   

  1. Department of Otorhinolaryngology & Head and Neck Surgery, Zhongshan People's Hospital, Zhongshan 528403, Guangdong, China
  • Published:2021-08-05

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Abstract: Objective To compare the clinical efficacies of holmium and CO2 lasers in the treatment of early glottic carcinoma. Methods The clinical data of 91 patients with early glottic laryngeal carcinoma treated by laser surgery were retrospectively analyzed(Tis, T1N0M0). Based on the treatment methods, the patients were divided into the holmium(56 cases)and CO2(35 cases)laser surgery groups. The duration of surgery, blood loss, complications, hospital stay, wound recovery time, and survival rate were analyzed in the two groups. Results There were no statistically significant differences between the postoperative pain scores(P=0.55), hospital stay durations(P=0.99), complications rates(P=0.43), recurrence rates(P=0.59), and laryngeal preservation rates of the Holmium and CO2 laser groups(P=0.64). The blood loss(P=0.02)and the durations of surgery(P<0.01)and wound healing of the two groups(P<0.01)were statistically significant. There was no significant difference between the 3-year survival rates of the two groups(P=0.69). Conclusion Holmium and CO2 laser cordectomies have the same effect in the treatment of early glottic carcinoma, and the duration of the former is shorter. With familiarity with the application of the two types of laser, patients can avoid open surgery and undergo minimally invasive treatment of tumors.

Key words: Early glottic carcinoma, Holmium laser, CO2 laser, Laser surgery, Survival rate

CLC Number: 

  • R766.9
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