Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2026, Vol. 40 ›› Issue (2): 35-43.doi: 10.6040/j.issn.1673-3770.0.2025.012

• Original Article • Previous Articles     Next Articles

Characteristics and influencing factors of anxiety and depression in patients with chronic frontal sinusitis

ZHAI Xuechun, BIAN Xin, CHEN Jingcai, DENG Jiayu, YE Zi, YANG Pingli   

  1. Department of Otolaryngology, The First Affiliated Hospital of Shihezi University, Shihezi 832008, Xinjiang, China
  • Published:2026-03-26

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Abstract: Objective To investigate the characteristics of anxiety and depression in patients with chronic frontal sinusitis and to explore whether frontal sinusitis symptoms constitute risk factors for anxiety and depression in patients. Methods A prospective cohort of 126 patientswith confirmed chronic frontal sinusitis was enrolled. All patients were assessed via questionnaires, including the Zung Self-Rating Anxiety Scale(SAS), the Zung Self-Rating Depression Scale(SDS), the symptom visual analog scale(VAS), the 22-item Sino-Nasal Outcome Test(SNOT-22), Lund-Mackay CT scoring system, and Lund-Kennedy endoscopic score to assess psychological status, quality of life, and disease severity preoperatively. Results were compared with Chinese standard norms and subjected to statistical analysis. Results Among the 120 effective cases, 27.50% ofpatients exhibited varying degrees of anxiety and 30.00% showed varying degrees of depression prior to surgery. Anxiety and depression levels were significantly higher than the Chinese normative values, with statistically significant differences(t=10.906, P<0.001; t=2.162, P=0.031). There was no significant difference in terms of age, gender, presence of diabetes or hypertension, endoscopic score, or CT score between the normal control subjects and patients with anxiety or depression levels(P>0.05). Nasal itching, tearing, coughing, wheezing, dizziness headaches, and sleep problems are independent risk factors for increased anxiety in patients with chronic frontal sinusitis; nasal discharge, eye redness and swelling, and sleep problems are independent risk factors for increased depression in patients with chronic frontal sinusitis(P<0.05). Conclusion Patients with chronic frontalsinusitis exhibit significantly higher levels of preoperative anxiety and depression compared to the general population. Increased symptom severity elevates anxiety and depression levels, while sleep disturbances serve as a common independent risk factor exacerbating these conditions. Enhanced psychological assessment and intervention are warranted to improve treatment outcomes and patient quality of life.

Key words: Chronic rhinosinusitis, Frontal sinusitis, Anxiety, Depression, Cross-sectional study

CLC Number: 

  • R765.43
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