JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY)

• Articles • Previous Articles     Next Articles

Effect of microwave radiation on cell proliferation activity and the cell cycle of nasopharyngeal carcinoma

MA Jing1, LIU Bin2   

  1. 1. Department of Otorhinolaryngology； 2. Department of Pathology, Lanzhou General Hospital, Lanzhou Command, Chinese PLA, Lanzhou 730050, China

  • Received:1900-01-01 Revised:1900-01-01 Online:2008-08-16 Published:2008-08-16
  • Contact: MA Jing

PDF (PC)

1479

Abstract:

Objective〓〖WTBZ〗To explore the effect of microwave radiation on cell proliferation activity and the cell cycle of nasopharyngeal carcinoma. 〖WTHZ〗Methods〓〖WTBZ〗There were four groups: the control, 10, 20 and 30mW/cm2 microwave radiation groups. MTT and flow cytometry (FCM) methods were used to detect the cell proliferation activity and the cell cycle of nasopharyngeal carcinoma. 〖WTHZ〗Result〓〖WTBZ〗With an increase of microwave radiation dosage, the MTT assay showed that the rate of cell activity was reduced from 100% to 76.75% and 65.07% at 20 and 30 mW/cm2 microwave radiation and sub-diploidy peaks were found. 〖WTHZ〗Conclusion〓〖WTBZ〗Microwave radiation inhibits cell proliferation and promotes cell apoptosis of nasopharyngeal carcinoma.

Key words: Nasopharyngeal carcinoma, Cell cycle,

Microwave, Apoptosis

CLC Number: 

  • R739.65
[1] ZHANG Caixia, LIU Yangyun, JIANG Wen, LIU Gengxun, CAO Hang, CHEN Qiong, ZHANG Jishuai. Investigation of chemosensitization induced by nitric oxide on nasopharyngeal carcinoma CNE-2 cells. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(5): 72-78.
[2] ZHOU Yibo, GONG Xiaorong, YU Feng. Effects of miR-150 targeted to Nanog on proliferation and invasion of nasopharyngeal carcinoma side population cells. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(5): 79-84.
[3] DU Zhihong. Application of oro-nasal combination approach under electronic nasopharyngoscope in the nasopharyngeal biopsy. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 117-118.
[4] . Effects of concurrent chemotherapy and radiotherapy on the quality of life in children and adolescents with nasopharyngeal carcinoma. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(2): 55-58.
[5] . Construction of c-Met target chimeric antigen receptor T cells and evaluation the role on nasopharyngeal carcinoma cells. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(2): 49-54.
[6] . Efficacy of recombinant human epidermal growth factor in prevention of radioactive oral mucosa inflammation and acute radiation dermatitis for nasopharyngeal carcinoma. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(1): 95-99.
[7] WANG Yaning, GENG Bo, LI Baiyan, CUI Chaoyang, WANG Qirong. The treatment experience on osteoradionecrosis of skull base with nasopharyngeal carcinoma after radiotherapy. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(6): 42-45.
[8] LIU Ye, SUN Dianshui, YIN Jinjun, XIA Ming, XU Ying, SUN Jianhua. Vestibular function damage mechanisms in nasopharyngeal carcinoma patients after intensity-modulated radiotherapy. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(6): 14-17.
[9] WANG Junying, LI Xiaofeng. Effect of deproteinized extract of calf blood gel eye on the injury of corneal endothelial cells after nasopharyngeal carcinoma radiotherapy. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(1): 76-79.
[10] ZHAO Yanlian, LU Yongtian, YANG Jihong, ZHANG Juan, MIAO Fangfang, LI Jieping. Relationship between the expression of EGFL7 in nasopharyngeal carcinoma and the invasion and metastasis of tumor [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(6): 31-35.
[11] CHE Juan, ZHAO Hongchun, LI Jinling, WANG Yanfei. The relationship between D-Dimer and nasopharyngeal carcinoma [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(5): 47-49.
[12] ZHANG Xiao-peng1, BIAN Feng2, WANG Li-xin2. Expressions and relativity of COX-2 and EGFR in nasopharyngeal carcinoma [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(3): 23-27.
[13] SHI Da-zhi1, LI Jian-ming2, LUO Zhi-qiang1, LUO Qin1, JING Qian-cheng1. Clinical analysis of nasopharyngeal carcinoma in pregnancy [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(3): 28-30.
[14] ZHANG Zhong-hua1, WANG Xue-hai2, CAI Xiao-lan3. Expression and significance of p-PTEN， p-Akt and p-FoxO1 in nasopharyngeal carcinoma [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(2): 55-57.
[15] YANG Jian-ming. Relationship between radioactive otitis media and changes in cross section area of tensor veli palatine (TVP) muscle after radiotherapy in patients with nasopharyngeal carcinoma [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(1): 31-33.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd