JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (6): 90-93.doi: 10.6040/j.issn.1673-3770.0.2016.061

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Discussion on the relationship between vocal cord leukoplakia and premalignant lesions and research progress of vocal cord leukoplakia.

WANG Yalin1, CHEN Jianqiu2   

  1. 1. Second Clinical College of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong, China;2. Department of Otolaryngology &Head and Neck Surgery, General Hospital of Jinan Military Region, Jinan 250031, Shandong, China
  • Received:2016-02-20 Online:2016-12-16 Published:2016-12-16

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Abstract: Vocal cord leukoplakia is a white-plaque disease due to long-term stimulation on vocal cords, which includes abnormal epithelial hypertrophy and dysplasia of the vocal cord. The term “white plaque” is clinically describing any white lesion on a mucous membrane that cannot be wiped off or ascribed to any specific condition(eg, Candidal infection). There is a consensus that vocal cord leukoplakia has no histologic implications and synonymous with cancer or malignancy, only as a clinical descriptive diagnosis. In this paper, we reviewed the relationship between vocal cord leukoplakia and premalignant lesions and the formation mechanism, histopathologic classification, clinical diagnosis and treatment of vocal cord leukoplakia.

Key words: Vocal cord leukoplakia, Premalignant lesions

CLC Number: 

  • R762
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