Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (4): 25-30.doi: 10.6040/j.issn.1673-3770.1.2019.029

• Reseach Progress • Previous Articles     Next Articles

Etiology, molecular mechanisms, and treatment strategies of precancerous laryngeal lesions

Yupeng SHEN,Qi SONG,Xiaoming LI*()   

  1. Department of Otorhinolaryngology Head and Neck Surgery, Bethune Peace Hospital, Shijiazhuang 050082, Hebei, China
  • Received:2019-05-10 Online:2019-07-16 Published:2019-07-22
  • Contact: Xiaoming LI E-mail:xmlmo@126.com

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Abstract:

Laryngeal precancerous lesions refer to several types of laryngeal lesions with malignant potential, which present with similar clinical manifestations, pathological features, and biological characteristics. Common laryngeal precancerous lesions include laryngeal keratosis, chronic hypertrophic laryngitis, papilloma of larynx, etc. There are many pathogenic factors associated with laryngeal precancerous lesions. The prognosis is dependent on where the lesion occurs and how it develops, as there are various molecular mechanisms involved in the regulative progress. The clinical treatment strategy for laryngeal precancerous lesions depends on an individualized surgical plan. Future clinical research will focus on efforts to prevent and block the pathogenic factors of laryngeal precancerous lesions.

Key words: Laryngeal precancerous lesion, Etiology, Molecular mechanism, Treatment outcome

CLC Number: 

  • R739.6
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