Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2025, Vol. 39 ›› Issue (5): 97-100.doi: 10.6040/j.issn.1673-3770.0.2023.337

• Original Article • Previous Articles    

Primary epiglottic neuroendocrine carcinoma: a case report and literature review

LIU Yuzhu1, YUAN Tiejun1, LI Bo2   

  1. 1. Department of Otolaryngology, Weifang People's Hospital, Weifang 261044, Shandong, China 2. Department of Rehabilitation Medicine, Weifang Yidu Central Hospital, Weifang 262500, Shandong, China
  • Published:2025-09-19

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Abstract: Objective This study aims to investigate the clinical manifestations, pathological types, treatment modalities, and prognosis of laryngeal neuroendocrine carcinoma. Methods The clinical data from a case of neuroendocrine carcinoma are presented, accompanied by a comprehensive review of related literature. Results A diagnosis of laryngeal neuroendocrine carcinoma was primarily established through pathological examination. The literature revealed significant differences in biological behavior, treatment approaches, and prognosis among various pathological types. Conclusion The best practice for treating laryngeal neuroendocrine carcinoma remains controversial, with no established gold standard treatment plan in cases where postoperative lymph nodes show metastasis, radiotherapy may contribute to an improved prognosis However, for patients with negative lymph nodes, the necessity of radiotherapy and chemotherapy remains uncertain.

Key words: Epiglottis, Neuroendocrine carcinoma, Throat, Radiotherapy

CLC Number: 

  • R767.5
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