Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (1): 67-72.doi: 10.6040/j.issn.1673-3770.1.2018.030

Previous Articles     Next Articles

Characteristics of the distribution of inhaled allergens in patients with allergic rhinitis in Qingdao from 2008 to 2017

QIN Ya′nan, WANG Lin, JIANG Yan, YAN Shu, CHEN Min, YU Longgang, LI Na   

  1. Department of Otolaryngology Head and Neck Surgery, Allergy, Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong, China
  • Online:2019-01-20 Published:2019-01-28

PDF (PC)

318

Abstract: Objective To study the characteristics of the distribution of common inhaled allergens in a populations of allergic rhinitis patients in Qingdao over the past ten years. Methods The skin prick test was performed on 4 737 patients with allergic rhinitis who visited the hospital in Qingdao from 2008 to 2017. Commonly inhaled allergens in Qingdao were selected for detection and the results were statistically analyzed. Results The five most common allergens that had a positive result on the skin prick test were dust mites, house dust mites, cockroaches, Artemisia grandis pollen, and sycamore pollen. Locust tree pollen caused a mild allergic reaction, while other allergens caused mainly moderate or moderately severe allergic reactions. The highest rate of dust mite allergy appeared from August to January. The highest rate of Artemisia sphaerocephala pollen and ragweed pollen allergies appeared in the summer. The highest rate of sycamore pollen allergy appeared from May to August. The highest rate of ash tree pollen allergy appeared in the spring and autumn. The highest positive rate of cockroach allergy appeared in September. The highest rate of cat and dog hair, and yellow-producing penicillium allergy appeared in summer. Among the allergic patients, those who were allergic to two or three allergens at the same time comprised the majority of the sample, and those who were allergic to a single allergen or four or more allergens comprised a smaller proportion of the sample. The highest rate of dust mite and yellow-producing penicillium allergy appeared in patients aged 7-17 years, while the highest rate for other allergies appeared in patients aged 18-40 years. There was no significant difference between the male and female populations in the rate of dust mite, house dust mite, wormwood pollen, or sycamore pollen allergy; the female population had a higher rate of allergy to ragwort pollen, locust tree pollen, cat hair, dog hair, and yellow-producing mildew than the male population, and the male populations had a higher rate of allergy to cockroaches than the female population. Conclusion The main inhaled allergens causing allergic rhinitis in the Qingdao area in the past ten years were dust mites, cockroaches, and pollen. Among the allergic patients, those who were allergic to two allergens at the same time comprised the majority of the group. The highest rate of dust mite allergy appeared in July and November. The highest rate of pollen allergy appeared in the spring and autumn. The highest rate of animal hair and mold allergy appeared in the summer. Most allergies were most common in the 18-40-year-old age group. There was no difference in the rates of dust mite, Artemisia pollen, or sycamore pollen allergy between sexes. Sex differences were present for other allergens.

Key words: Inhalation allergens, Allergic rhinitis, Skin prick test, Epidemiology

CLC Number: 

  • R765.22
[1] Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma(ARIA)2008 update(in collaboration with the World Health Organization, GA(2)LEN and AllerGen)[J]. Allergy, 2008, 63(Suppl 86):8-160. doi:10.1111/j.1398-9995.2007.01620.x.
[2] Zhang Y, Zhang L. Prevalence of allergic rhinitis in China[J]. Allergy Asthma Immunol Res, 2014, 6(2):105-113. doi:10.4168/aair.2014.6.2.105.
[3] Aït-Khaled N, Pearce N, Anderson HR, et al. Global map of the prevalence of symptoms of rhinoconjunctivitis in children: The International Study of Asthma and Allergies in Childhood(ISAAC)Phase Three[J]. Allergy, 2009, 64(1):123-148. doi:10.1111/j.1398-9995.2008.01884.x.
[4] 王成硕, 张罗, 韩德民, 等. 北京地区变应性鼻炎患者吸入变应原谱分析[J]. 临床耳鼻咽喉科杂志, 2006, 20(5):204-207. doi:10.3969/j.issn.1001-1781.2006.05.004. WANG Chengshuo, ZHANG Luo, HAN Demin, et al. Prevalence of sensitization to aeroallergens in Beijing patients with allergic rhinitis[J]. Journal of Clinical Otorhinolaryngology, 2006, 20(5):204-207. doi:10.3969/j.issn.1001-1781.2006.05.004.
[5] 高荣莉, 丁见, 臧延伟, 等. 青岛地区变应性鼻炎流行病学调查研究[J]. 山东大学耳鼻喉眼学报, 2012, 26(2):55-60. GAO Rongli, DING Jian, ZANG Yanwei, et al. Epidemiological investigation of allergic rhinitis in the Qingdao area[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2012, 26(2):55-60.
[6] 王鹏, 李伟, 赵平, 等. 武汉市青山地区637例变应性鼻炎患者变应原种类分析[J]. 临床耳鼻咽喉头颈外科杂志, 2008, 22(14):634-636. doi:10.3969/j.issn.1001-1781.2008.14.004. WANG Peng, LI Wei, ZHAO Ping, et al. Prevalence of sensitization to allergens in patients with allergic rhinitis and respiratory disease in Qingshan of Wuhan[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2008, 22(14):634-636. doi:10.3969/j.issn.1001-1781.2008.14.004.
[7] 张秋贵, 何海燕. 青岛地区变应性鼻炎常见变应原调查分析[J]. 山东大学耳鼻喉眼学报, 2006, 20(6):520-521. doi:10.3969/j.issn.1673-3770.2006.06.013. ZHANG Qiugui, HE Haiyan. Allergens in patients with allergic rhinitis in Qingdao area[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2006, 20(6):520-521. doi:10.3969/j.issn.1673-3770.2006.06.013.
[8] 刘杰, 鹿道温, 郭艳丽, 等. 青岛地区气传花粉及其致敏性调查[J]. 中国中西医结合耳鼻咽喉科杂志, 2012, 20(6):471-477. doi:10.3969/j.issn.1007-4856.2012.06.028. LIU Jie, LU Daowen, GUO Yanli, et al. Investigations on airborne pollens and its allergenicity in Qingdao district[J]. Chinese Journal of Otorhinolaryngology in Integrative Medicine, 2012, 20(6):471-477. doi:10.3969/j.issn.1007-4856.2012.06.028.
[9] 叶世泰.中国气传致敏花粉调查[M].北京:北京出版社,1991: 120-125.
[10] 于斌, 鹿道温, 刘杰. 青岛地区豚草花粉症85例[J]. 山东大学耳鼻喉眼学报, 2007, 21(6):537-539. doi:10.3969/j.issn.1673-3770.2007.06.020. YU Bin, LU Daowen, LIU Jie. Ragweed pollenosis in the Qingdao area: a report of 85 cases[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2007, 21(6):537-539. doi:10.3969/j.issn.1673-3770.2007.06.020.
[11] 陈艳丽, 徐小玲, 张婧, 等. 不同地区变应性鼻炎患者吸入性变应原的分布研究[J]. 河北医药, 2012, 34(5):754-755. doi:10.3969/j.issn.1002-7386.2012.05.069.
[12] 陈建军, 孔维佳, 项济生, 等. 湖北地区变应性鼻炎变应原年龄特征分析[J]. 临床耳鼻咽喉头颈外科杂志, 2008, 22(15):683-685,694. doi:10.3969/j.issn.1001-1781.2008.15.004. CHEN Jianjun, KONG Weijia, XIANG Jisheng, et al. Age features of the allergens in allergic rhinitis patients of different age in Hubei area[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2008, 22(15):683-685,694. doi:10.3969/j.issn.1001-1781.2008.15.004.
[13] 黄芳, 赵艳, 何荆培, 等. 荆门地区变应性鼻炎患者吸入变应原谱分析[J]. 临床耳鼻咽喉头颈外科杂志, 2010, 24(8):341-343. doi:10.3969/j.issn.1001-1781.2010.08.002. HUANG Fang, ZHAO Yan, HE Jingpei, et al. Analyzing of the inhaled allergens profiles of allergic rhinitis patients in district of Jingmen[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2010, 24(8):341-343. doi:10.3969/j.issn.1001-1781.2010.08.002.http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=lcebyhkzz201008002
[14] Colonna-Romano G, Bulati M, Aquino A, et al. B cell immunosenescence in the elderly and in centenarians[J]. Rejuvenation Res, 2008, 11(2):433-439. doi:10.1089/rej.2008.0664.
[15] 任秀敏, 孙称心, 段乃超, 等. 石家庄地区994例变应性鼻炎患者吸入性变应原检测分析[J]. 中国耳鼻咽喉颅底外科杂志, 2010, 16(1):43-46,49. REN Xiumin, SUN Chenxin, DUAN Naichao, et al. Aeroallergen analysis of 994 patients with allergic rhinitis in Shijiazhuan[J]. Chinese Journal of Otorhinolaryngology-Skull Base Surgery, 2010, 16(1):43-46,49.
[16] 张罗,王成硕,王向东.变应性鼻炎诊治进展[J].中国实用内科杂志,2012,32(2):86-88.
[17] 马莉, 蓝绍颖, 顾国荣, 等. 江苏省南通地区变应性鼻炎1200例变应原调查研究[J]. 南通医学院学报, 2009, 29(6):461-462. doi:10.3969/j.issn.1674-7887.2009.06.022.
[18] 程雷. 变应性鼻炎的诊断和治疗[J]. 山东大学耳鼻喉眼学报, 2013, 27(2):1-4.
[1] DU Jingwei, FENG Jun, MA Peng, LI Zhiyong, LI Hongguang. Effect of nasal irrigation combined with intranasal corticosteroids to treat allergic rhinitis and influence on exhaled nitric oxide and lung function [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 124-127.
[2] HONG Dongdong, LIU Yuanxian, ZOU Lianqiang, WENG Juanling, DENG Wenxian. An analysis of 764 positive skin prick test results for Dermatophagoides farinae in patients with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 119-123.
[3] QI Yan, LIU Junqi, PENG Shuya, LUO Kai, ZHANG Mingxia, WANG Zhenlin. Therapeutic ecacy of endoscopic elective vidian neurectomy for moderate-severe persistent allergic rhinitis with chronic sinusitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 109-113.
[4] Yinshi GUO,Hui LU. Research progress of group Ⅱ innate lymphoid cells in the allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 9-12.
[5] CAO Cheng, XU Yu. Clinical compliance and related factors to sublingual immunotherapy in patients with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 114-118.
[6] Qianhui QIU,Junxiao GAO. Synchronous control and long-term efficacy of specific immunotherapy for allergic rhinitis and asthma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 33-37.
[7] JIN Xing, HU Dayu, ZHU Li, DENG Furong, LIU Junxiu. Correlation between PM2.5 and upper airway resistance in patients with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 77-80.
[8] LI Lisha, GUAN Kai, WANG Zixi, CUI Le. The effects of air pollutants on the severity of allergic rhinitis symptoms caused by cypress pollen [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 81-87.
[9] HONG Haiyu, XU Guangfu, YANG Shuowei, SU Rongfei, HUANG Yili, CHI Mengshi,WANG Weihao,YANG Qintai. The prevalence and risk factors of bronchial asthma in patients with allergic rhinitis in Guangdong Province [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 94-98.
[10] LU Hangui, LIN Xinsheng, YAO Danmian, WEI Yongxin, LI Chuangwei. Expression of IL-35 in allergic rhinitis and its effect on the immunoregulation of T cells [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 66-70.
[11] WANG Tan, WU Ke, LI Lianqing, GONG Lili. Factors associated with systemic adverse reactions after subcutaneous immunotherapy injections and treatment options [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 71-74.
[12] PU Hongbo, DU Xiaodong. Allergen test results in 2 000 patients with allergic rhinitis in Wuxi District [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(4): 105-107.
[13] CHEN Ming, YU Xuefei. Opinions on the treatment of chronic rhinosinusitis with allergic rhinitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 18-22.
[14] WU Xiangping. Influence of patient management on the clinical effect of sublingual dermatophagoides farinae drops in patients [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 68-72.
[15] LI Song, WANG Zonggui, YANG Jingpu, ZHANG Zhuping. Progress of transnasal endoscopic vidian neurectomy [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(1): 72-76.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] WANG Xiao-feng,LIN Chang,CHENG Jin-mei . Expression of ABAD in inner ears and its clinical significance in different age mice[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 207 -211 .
[2] LIU Yan,LIU Xin-yi,WANG Jin-ping,LI Da-jian . Measurement of the posterior tympanum and its clinical significance [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 218 -221 .
[3] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 222 -224 .
[4] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 227 -227 .
[5] LIN Feng,LIANG Yong,LU Yong-tian,WAN Li-xia . Classification and surgical treatment for nasal inverted papilloma[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 231 -233 .
[6] YU Zhi-liang,WANG Wei-wei,WANG Ming-hua . Excision of huge epiglottis cysts under MedtrnicXPS3000 in 23 cases[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 278 -279 .
[7]
YIN Guo-hua,ZHONG Xiao . Long-term effect of laser reduction on lingua adenoids
[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 280 -282 .
[8]

CAI Qian,SU Zhen-zhong,WEN Wei-ping,CHAI Li-ping,YE Hui,TENG Yi-shu,WU Xuan

. Relationship between adult snoring and oropharyngeal stenosis scoring[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 289 -292 .
[9] SUN Yan,ZHANG Qing-quan,ZHANG Hua,SONG Xi-cheng,ZHAO Li-min,WANG Yan,JIANG Shao-hong,WANG Qiang . Heterogenerty (cattle) acellular dermal matrix repairing mucosa in otolaryngology reconstruction surgeries[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 316 -319 .
[10] MA Jing,LIU Bin .

Effect of microwave radiation on cell proliferation activity and the cell cycle of nasopharyngeal carcinoma

[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 310 -312 .
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd