他汀类药物在过敏性疾病中的治疗作用探讨

doi:10.6040/j.issn.1673-3770.0.2022.410

Abstract

Abstract: Allergic diseases are a common group of chronic conditions with continuously increasing prevalence. These diseases adversely affect the quality of life of patients. The research and development of new drugs with effective treatment and reasonable price need to continue. In recent years, in addition to lowering blood lipid levels, statins have pleiotropic properties and exert anti-inflammatory, antioxidant, and immunomodulatory effects. A series of animal experiments and clinical trials have confirmed the therapeutic effects of statins against allergic inflammation. Their specific mechanism of action and clinical effects in allergic diseases are the focus of current research, which is of great significance for the clinical application of them. In this article, the research progress of clinical intervention of statins in the treatment of allergic diseases is introduced, and the research progress of the therapeutic mechanism of statins in allergic diseases is reviewed.

Key words: Statins, Allergic Diseases, Immunity, Dyslipidemia, Mevalonic acid

CLC Number:

R392.8

DONG Lin, WEN Silu, DENG Yuqin, TAO Zezhang. Therapeutic role of statins in allergic diseases[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(1): 106-114.

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