Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2024, Vol. 38 ›› Issue (4): 36-42.doi: 10.6040/j.issn.1673-3770.0.2023.393

• Original Article • Previous Articles    

Study on the correlation between allergic rhinitis and coronavirus disease-2019 infection and symptoms in children

ZHANG Jie1,2, CHEN Min1, SHEN Zhengzheng2, WU Yuhua2, LIU Yuanhu1, SUN Hao2, TAN Xinhua2, NI Shuren2, YANG Shuxun2, SHI Xuezheng2, NI Xin1   

  1. 1. Department of Otorhinolaryngology & Head and Neck Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China2. Department of Otorhinolaryngology & Head and Neck Surgery, Shunyi Women's & Children's Hospital of Beijing Children's Hospital, Beijing 101300, China
  • Published:2024-07-09

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Abstract: Objective This study examined the potential impact of allergic rhinitis on children's susceptibility to and experience of coronavirus disease-2019(COVID-19)infection. Methods A retrospective analysis was conducted on 205 outpatients. Clinical data were collected through a questionnaire that assessed general information, presence of allergic rhinitis, and COVID-19 infection status. A visual analog scale was used to score the severity of COVID-19 symptoms across body areas. Chi-square and non-parametric tests were used to compare the differences in age, sex, and allergic rhinitis prevalence between the COVID-19 infection and non-infection groups. Linear regression analysis explored factors influencing symptom severity in the infection group. Results No significant association was found between COVID-19 infection and age, sex, allergic rhinitis, or other factors. Among the 152 children infected with COVID-19, age showed a positive correlation between symptom scores between children with and without allergic rhinitis. Conclusion In children, allergic rhinitis appears to have minimal impact on COVID-19 infection susceptibility, symptoms severity, or disease duration. While age demonstrated a positive correlation to the severity of throat symptoms in children with COVID-19, allergic rhinitis status was not a significant factor.

Key words: Pediatric COVID-19, Allergic rhinitis, Influencing factors, Age, Angiotensin converting enzyme 2

CLC Number: 

  • R765.21
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