头颈肿瘤患者术前血C-反应蛋白水平测定的临床意义

山东大学耳鼻喉眼学报

头颈肿瘤患者术前血C-反应蛋白水平测定的临床意义

陈志俊¹，牟莹心²，王萍³

1. 青岛大学医学院附属医院耳鼻咽喉-头颈外科，山东青岛 266003；2. 青岛市立医院检验科，山东青岛 266003； 3. 青岛市立医院内科，山东青岛 266003

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-08-24 发布日期:2007-08-24
通讯作者: 陈志俊

C-reactive protein level of patients with head and neck tumor before operation

CHEN Zhi-jun¹，MU Ying-xin²，　WANG Ping³

1. Department of Otolaryngology & Head and Neck Surgery, Affiliated Hospital of Medical College of Qingdao University;2. Department of Clinical Laboratory,3. Department of Medicine, Qingdao Municiple Hospital, Qingdao 266003

Received:1900-01-01 Revised:1900-01-01 Online:2007-08-24 Published:2007-08-24
Contact: CHEN Zhi-jun

摘要/Abstract

摘要： 目的：探讨头颈肿瘤患者术前血中C-反应蛋白(C-reactive protein, CRP)水平与术后感染的关系。方法: 以177例晚期头颈肿瘤外科手术患者为研究对象，手术前1d常规行血CRP、清蛋白以及白细胞计数检查，并分析术后感染的相关资料。结果:术后发生感染21例（11.9%），术前CRP水平明显高于未感染患者，两组差异有统计学意义（t=2.835，P ＜0.01)。术前CRP水平升高患者术后感染率为57.14%，明显高于CRP水平正常组的3.36%(χ2=6.18,P＜0.01)；术前CRP升高患者术后住院时间明显长于CRP正常组，差异有统计学意义(t=2.215，P＜0.05)。结论：头颈肿瘤患者术前血清CRP水平升高者术后发生感染的危险明显升高。

关键词: C-反应蛋白质, 感染, 头颈肿瘤

Abstract: Objective： To investigate the relationship of C-reactive protein(CRP) level of patients with head and neck tumor before operation and the infection after operation. Methods: The content of CRP, ABL and WBC in 177 patients with head and neck tumor preoperative 1day was determined. The data of C-reactive protein and infection after operation were analyzed by a statistical method. Results: Twentyone patients (11.9%) had infection after operation, whose CRP level was much higher than patients without infection (t=2.835，P＜0.01)．The infection rate of patients with an increased CRP level was significant higher than that with a normal CRP level　(χ2=6.18,P＜0.01). Moreover, the admission period was obviously prolonged (t=2.215，P＜0.05)．Conclusion: As the serum CRP is raised in patients with head and neck tumor before operation, the infection risk significantly increases after operation.

Key words: C-reactive protein, Infection, Head and neck neoplasms

中图分类号:

R739.91

陈志俊,牟莹心,王萍 . 头颈肿瘤患者术前血C-反应蛋白水平测定的临床意义[J]. 山东大学耳鼻喉眼学报, 2007, 21(4): 357-359 .

CHEN Zhi-jun,MU Ying-xin,WANG Ping . C-reactive protein level of patients with head and neck tumor before operation[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2007, 21(4): 357-359 .

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