山东大学耳鼻喉眼学报 ›› 2019, Vol. 33 ›› Issue (4): 6-9.doi: 10.6040/j.issn.1673-3770.1.2019.037

• 专家笔谈 • 上一篇    下一篇

早期声门癌的内镜治疗

刘鸣*()   

  1. 哈尔滨医科大学附属第二医院耳鼻咽喉头颈外科,黑龙江 哈尔滨 150086
  • 收稿日期:2019-06-02 出版日期:2019-07-16 发布日期:2019-07-22
  • 通讯作者: 刘鸣 E-mail:liumingorl@qq.com
  • 作者简介:刘鸣,教授,二级教授,主任医师,博士(PhD),博士后,博士生导师,科主任,教研室主任,哈医大二院五官医院副院长。黑龙江省领军人才梯队带头人,黑龙江省级重点学科带头人,哈尔滨医科大学优势学科带头人,黑龙江省卫生系统有突出贡献中青年专家,黑龙江省首届“龙江名医”,中国医师协会耳鼻咽喉科医师分会第四届《名医奖》。主要学术任职:2008~2015年担任黑龙江省医学会耳鼻咽喉头颈外科分会主任委员;中华医学会耳鼻咽喉头颈外科分会第九、十、十一届全国委员。现任黑龙江省医师协会耳鼻咽喉科分会主任委员,黑龙江省耳鼻咽喉医疗质量控制中心主任,中华医学会耳鼻咽喉头颈外科分会头颈外科学组顾问,中国医师协会耳鼻咽喉科分会常务委员、头颈学组副组长,中国抗癌协会头颈外科专业委员会常务委员,中国医疗保健国际交流促进会耳鼻咽喉科分会常务委员。《中华耳鼻咽喉头颈外科杂志》等期刊编委,全国高等学校五年制本科临床医学专业教材《耳鼻咽喉头颈外科学》(第九版)编委

Transoral laser microsurgery for early glottic neoplasms

Ming LIU*()   

  1. Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, Heilongjiang, China
  • Received:2019-06-02 Online:2019-07-16 Published:2019-07-22
  • Contact: Ming LIU E-mail:liumingorl@qq.com

摘要:

随着微创技术的不断成熟,早期声门型癌大多采取内镜下手术治疗。自上个世纪70年代CO2激光引入早期喉癌的治疗以来,因其无颈部及气管切开、术后并发症少、住院时间短、病人恢复快、喉功能保存好等优点,越来越被广泛应用,已被公认为首选的内镜手术方式。就经口CO2激光治疗早期声带癌的适应证、并发症、局限性、手术分型等内容进行讨论,在综述早期声门癌内镜治疗的历史及发展的同时,特别强调早期声带癌内镜手术中遵循肿瘤外科原则的重要性。

关键词: 声门, 喉肿瘤, 喉功能保留, 激光手术, 治疗结局

Abstract:

With the development of minimally invasive technology, most of early glottic carcinoma is treated by endoscopic surgery. Since CO2 laser was introduced into the treatment of early laryngeal carcinoma in the 1970s, it is widely due to its advantages. It does not require an neck incision and tracheotomy, and it is associated with less postoperative complications, shorter hospital stay, faster rapid recovery of patients, better preservation of laryngeal function and so on. Surgery with CO2 is recognized as the preferred endoscopic surgery for treating glottic cancers. The indications, complications, limitations and surgical classification of oral CO2 laser in the treatment of early vocal cord carcinoma are discussed in this paper. In addition, the history and development of endoscopic treatment of early glottic carcinoma are reviewed, and the importance of the oncological principles during the surgery of malignant tumor are emphasized.

Key words: Glottis, Laryngeal neoplasms, Larynx function preservation, Laser surgery, Treatment outcome

中图分类号: 

  • R739.6
1 中华耳鼻咽喉头颈外科杂志编辑委员会头颈外科组, 中华医学会耳鼻咽喉头颈外科学分会头颈学组, 李晓明. 喉癌外科手术及综合治疗专家共识[J]. 中华耳鼻咽喉头颈外科杂志, 2014, 49 (8): 620- 626.
doi: 10.3760/cma.j.issn.1673-0860.2014.08.002
2 Brierley JD, Gospodarowicz MK, Wittekind C. UICC TNM classification of malignant tumours[M]. Eighth ed. Chichester: Wiley, 2017: 31-34.
3 David G. Pfster , Sharon Spencer , David Adelstein , et al. Head and Neck Cancers, Version 1.2019[J]. Journal of the National Comprehensive Cancer Network Jnccn, 2019, 17 (7): 847.
4 钱晔, 魏东敏, 李文明, 等. 喉室及声门下联合入路喉部分切除术[J]. 山东大学耳鼻喉眼学报, 2018, 32 (3): 115.
doi: 10.6040/j.issn.1673-3770.0.2018.062
QIAN Ye , WEI Dongmin , LI Wenming , et al. Partial excision of larynx by combined laryngeal and subglottic subtotal laryngectomy[J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32 (3): 115.
doi: 10.6040/j.issn.1673-3770.0.2018.062
5 American Society of Clinical Oncology , Pfister DG , Laurie SA , et al. American Society of Clinical Oncology clinical practice guideline for the use of larynx-preservation strategies in the treatment of laryngeal cancer[J]. J Clin Oncol, 2006, 24 (22): 3693- 3704.
doi: 10.1200/JCO.2006.07.4559
6 Abdurehim Y H , Yasin Y , et al. Transoral laser surgery versus radiotherapy: systematic review and meta-analysis for treatment options of T1a glottic cancer[J]. Head Neck, 2012, 34 (1): 23- 33.
doi: 10.1002/hed.21686
7 黄志刚,韩德民,倪鑫,等.声带癌T1病变的CO2激光治疗[J].耳鼻咽喉头颈外科, 1996, 3(3): 152-154. doi: 10.16066/j.1672-7002.1996.03.013
HUANG Zhigang, HAN Demin. CO2 laser surgery for T1 vocal cord carcinoma[J]. Chin Arch Otolaryngol-Head Neck Surg, 1996(3): 152-154. doi: 10.16066/j.1672-7002.1996.03.013
8 周梁, 吴海涛, 黄维庭, 等. CO2激光在声门型喉癌外科治疗中的应用[J]. 中华耳鼻咽喉头颈外科杂志, 2008, 43 (10): 742- 745.
doi: 10.3321/j.issn:1673-0860.2008.10.005
ZHOU Liang , WU Haitao , HUANG Weiting , et al. Treatment of glottic cancer with CO2 laser[J]. Chin J Otorhinolaryngol Head Neck Surg, 2008, 43 (10): 742- 745.
doi: 10.3321/j.issn:1673-0860.2008.10.005
9 刘吉祥, 王林, 杜建群. CO2激光微创手术治疗早期喉癌[J]. 中国中西医结合耳鼻咽喉科杂志, 2008, 16 (5): 349- 352.
doi: 10.3969/j.issn.1007-4856.2008.05.011
LIU Jixiang , WANG Lin , DU Jianqun . Carbon dioxide laser microsurgery for early glottic carcinoma[J]. Chin Otorhinolaryngol J Integr Med, 2008, 16 (5): 349- 352.
doi: 10.3969/j.issn.1007-4856.2008.05.011
10 卢仲明, 宋新汉, 张思毅, 等. 显微喉镜下二氧化碳激光手术治疗喉癌的远期疗效[J]. 中华肿瘤杂志, 2012, 34 (6): 473- 476.
doi: 10.3760/cma.j.issn.0253-3766.2012.06.016
LU Zhongming , SONG Xinhan , ZHANG Siyi , et al. Long-term outcome of CO2 laser microlaryngoscopic treatment for laryngeal cancer[J]. Chin J Oncol, 2012, 34 (6): 473- 476.
doi: 10.3760/cma.j.issn.0253-3766.2012.06.016
11 孙广滨, 周水淼, 王洋, 等. 早期声带癌侵犯组织深度的定量分析[J]. 中华耳鼻咽喉科杂志, 2003, 38 (2): 160.
doi: 10.3760/j.issn:1673-0860.2003.02.023
12 李文明, 魏东敏, 钱晔, 等. 支撑喉镜下CO2激光治疗喉癌的疗效分析[J]. 山东大学耳鼻喉眼学报, 2018, 32 (6): 13- 17.
doi: 10.6040/j.issn.1673-3770.1.2018.025
Wenming LI , Dongmin WEI , Ye QIAN , et al. Evaluate the curative effect of CO2 laser in treatment of laryngeal carcinoma[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32 (6): 13- 17.
doi: 10.6040/j.issn.1673-3770.1.2018.025
13 吴娇娇, 黄志刚, 房居高, 等. CO2激光手术治疗喉癌的并发症分析[J]. 中华耳鼻咽喉头颈外科杂志, 2011, 46 (2): 118- 122.
doi: 10.3760/cma.j.issn.1673-0860.2011.02.007
WU Jiaojiao , HUANG Zhigang , FANG Jugao , et al. Complications of CO2 laser surgery in the treatment of laryngeal carcinoma[J]. Chin J Otorhinolaryngol Head Neck Surg, 2011, 46 (2): 118- 122.
doi: 10.3760/cma.j.issn.1673-0860.2011.02.007
14 许洪波, 房居高, 李平栋, 等. CO2激光喉手术中气管内燃烧的分级预防策略[J]. 中国耳鼻咽喉头颈外科, 2017, 24 (7): 333- 336.
doi: 10.16066/j.1672-7002.2017.07.002
XU Hongbo , FANG Jugao , LI Pingdong , et al. Grading prevention strategy for airway burn during CO2 laser surgery of larynx[J]. Chin Arch Otolaryngol-Head Neck Surg, 2017, 24 (7): 333- 336.
doi: 10.16066/j.1672-7002.2017.07.002
15 刘鸣, 田霖丽, 孙亚男, 等. 会厌癌CO2激光显微手术[J]. 中华耳鼻咽喉头颈外科杂志, 2013, 48 (6): 490- 494.
doi: 10.3760/cma.j.issn.1673-0860.2013.06.011
LIU Ming , TIAN Linli , SUN Yanan , et al. Transoral CO2 laser epiglottectomy for early epiglottic carcinomas[J]. Chin J Otorhinolaryngol Head Neck Surg, 2013, 48 (6): 490- 494.
doi: 10.3760/cma.j.issn.1673-0860.2013.06.011
16 黄志刚, 韩德民, 于振坤, 等. CO2激光手术治疗声门型喉癌疗效分析[J]. 中华耳鼻咽喉科杂志, 2002, 37 (3): 219- 222.
doi: 10.3760/j.issn:1673-0860.2002.03.017
HUANG Zhigang , HAN Demin , YU Zhenkun , et al. Evaluate the curative effect of CO2 laser in treatment of glottic carcinoma[J]. Chin J Otorhinolaryngol, 2002, 37 (3): 219- 222.
doi: 10.3760/j.issn:1673-0860.2002.03.017
17 Remacle M , Eckel HE , Antonelli A , et al. Endoscopic cordectomy. A proposal for a classification by the working committee, European laryngological society[J]. Eur Arch Otorhinolaryngol, 2000, 257 (4): 227- 231.
doi: 10.1007/s004050050228
18 Harris AT , Tanyi A , Hart RD , et al. Transoral laser surgery for laryngeal carcinoma: has Steiner achieved a genuine paradigm shift in oncological surgery?[J]. Ann R Coll Surg Engl, 2018, 100 (1): 2- 5.
doi: 10.1308/rcsann.2017.0190
19 Ambrosch P . The role of laser microsurgery in the treatment of laryngeal cancer[J]. Curr Opin Otolaryngol Head Neck Surg, 2007, 15 (2): 82- 88.
doi: 10.1097/MOO.0b013e3280147336
20 Steiner W , Ambrosch P , Rödel RM , et al. Impact of anterior commissure involvement on local control of early glottic carcinoma treated by laser microresection[J]. Laryngoscope, 2004, 114 (8): 1485- 1491.
doi: 10.1097/00005537-200408000-00031
21 Rucci L , Gammarota L , Gallo O . Carcinoma of the anterior commissure of the larynx: Ⅱ. Proposal of a new staging system[J]. Ann Otol Rhinol Laryngol, 1996, 105 (5): 391- 396.
doi: 10.1177/000348949610500512
22 Remacle M , Van Haverbeke C , Eckel H , et al. Proposal for revision of the European laryngological society classification of endoscopic cordectomies[J]. Eur Arch Otorhinolaryngol, 2007, 264 (5): 499- 504.
doi: 10.1007/s00405-007-0279-z
23 张庆翔, 李平栋, 胡慧英, 等. 累及前连合的早期声门型喉癌经口CO2激光治疗[J]. 中华耳鼻咽喉头颈外科杂志, 2015, 50 (4): 286- 289.
doi: 10.3760/cma.j.issn.1673-0860.2015.04.005
ZHANG Qingxiang , LI Pingdong , HU Huiying , et al. Transoral CO2 laser surgery for early glottic carcinoma with anterior commissure involvement[J]. Chin J Otorhinolaryngol Head Neck Surg, 2015, 50 (4): 286- 289.
doi: 10.3760/cma.j.issn.1673-0860.2015.04.005
[1] 周之航,刘素茹,周静,陈丹,杨佳静,刘蕊,周立. 声门闭合不全的病因及诊疗研究进展[J]. 山东大学耳鼻喉眼学报, 2025, 39(3): 97-103.
[2] 曾庆涵,吕丹. 单侧声带麻痹所致声门闭合不全的治疗进展[J]. 山东大学耳鼻喉眼学报, 2023, 37(5): 184-191.
[3] 文锋,张驰,扈希昊,董冰婉,秦永,赵恩民. 喉部腺样囊性癌4例并文献复习[J]. 山东大学耳鼻喉眼学报, 2023, 37(4): 119-125.
[4] 李利杰,田秀芬. CO2激光联合低温等离子治疗早期声门型喉癌40例[J]. 山东大学耳鼻喉眼学报, 2022, 36(4): 79-85.
[5] 毛泽凡陈曦,程雷. 喉神经内分泌癌的研究进展[J]. 山东大学耳鼻喉眼学报, 2022, 36(4): 114-119.
[6] 陈国平,傅敏仪,叶飞,徐建慧. 早期声门型喉癌钬激光与CO2激光手术对比研究[J]. 山东大学耳鼻喉眼学报, 2021, 35(4): 8-11.
[7] 吴允刚,张辉,孙聚兴,刘涛,王彩华,杨欣欣,马林祥,李笑颖,庞太忠,李晓瑜. 环甲膜联合喉室入路切除T1B声门型喉癌临床疗效分析[J]. 山东大学耳鼻喉眼学报, 2021, 35(4): 30-34.
[8] 石玉琦,佘翠平,张庆丰,刘得龙,焦梦思. 早期声门型喉癌低温等离子射频术后喉部感染诊治经验与教训[J]. 山东大学耳鼻喉眼学报, 2021, 35(4): 129-134.
[9] 孙浩,张杰,杨扬,倪树仁,吴宇华,刘原虎,倪鑫. 宫腔镜在声门暴露困难喉部手术中的应用[J]. 山东大学耳鼻喉眼学报, 2021, 35(3): 92-95.
[10] 周恩,肖禹,肖旭平. 等离子射频消融技术在早期声门型喉癌治疗中的应用进展[J]. 山东大学耳鼻喉眼学报, 2021, 35(2): 9-15.
[11] 肖旭平,周恩,肖禹. 等离子点状激发射频消融技术治疗早期声门型喉癌(Tis-T1b)31例[J]. 山东大学耳鼻喉眼学报, 2021, 35(2): 60-66.
[12] 张静祎,王文一,荣凌燕,张家奎,宋西成. 中药热奄包外敷联合七叶皂苷钠静滴治疗鼻部外伤肿胀疗效观察[J]. 山东大学耳鼻喉眼学报, 2020, 34(6): 21-26.
[13] 谭凤武,邓亚萍,黎可华. 低温等离子射频消融与CO2激光手术治疗早期声门型喉癌疗效的Meta分析[J]. 山东大学耳鼻喉眼学报, 2020, 34(6): 63-71.
[14] 顾晓娜,程向荣,张鹏,朱亮,滕华,王勇,胡晓燕,刘晓静. 支撑喉镜下喉显微手术患者的体位改进[J]. 山东大学耳鼻喉眼学报, 2020, 34(6): 77-81.
[15] 谷少尉,侯元友,魏东敏,李文明,陈东彦,徐晨阳,雷大鹏,潘新良. 声门上喉癌舌瓣修补术后吞咽功能恢复[J]. 山东大学耳鼻喉眼学报, 2020, 34(5): 127-131.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!