关键词: 喉肿瘤, 嗓音声学分析, 喉切除术, 喉功能重建

Abstract:

Objective    To explore the surgery way for T1 and T2 glottic carcinoma. Methods    From 2003 to 2010, small partial laryngectomy was performed on 112 patients with T1 or T2 (80 with T1N0M0 and 32 with T2N0M0 ) glottic carcinoma. By a retrospective review of the surgery approach, the curative results and advantages of the surgery treatment,  dynamic follow-up of the movement of the arytenoid cartilage,  reconstruction of the glottis rimae and the changes of the voice were analyzed. The pre-operative and post-operative voice qualities were compared with the software of Dr. Speech system for windows. Results    All patients were healed in one stage about 6 or 7 days and took food with mouth post-operatively 2 or 3 days, and the mean time of all patients with cannula was 7.3 days. The removal rate of the trachea cannula was 100 %. The movement of the arytenoid cartilage of 47 cases 1 week after surgery was weakened, the reconstructed glottis rimae  was close to be normal 6 months  after operation. There was no significant difference in Shimmer and NNE before and 1 week after operation(P>0.05), but there was significant difference before and 2 months and half a year  after operation, and there was also significant difference 1 week, 2 months and 6 months  after operation(P<0.01). 76 cases survived during 3 years′ follow-up, 35 of 36 cases survived in 5 years′ follow-up post-operatively (1 case died without definite causes). Conclusion    Partial laryngectomy achieves satisfied curative results and provides a clear operative view to resect the tumor completely, reconstruct the function of the larynx and improve the voice quality of the patients post-operatively. Therefore, partial laryngectomy is effective for T1 or T2(T1N0M0, T2N0M0) glottic carcinoma.

Key words: Reconstruction of larynx, Laryngectomy, Laryngeal neoplasm, Voice acoustic analysis