Abstract: Objective To evaluate and compare the effect of regional refractive intraocular lens implantation through a personalized surgical design in eyes with an angle alpha of less than or equal to 0.5 mm and 0.5-0.8 mm. Methods The patients were divided into two groups based on OPD examination before the surgery. The observation and control groups included patients with an angle alpha of 0.5-0.8 mm and less than or equal to 0.5 mm, respectively. Phacoemul-sification cataract extraction and regional refractive intraocular lens SBL-3 implantation were performed. The observation group used an individualized surgical design to determine the direction of intraocular lens placement. We compared the uncorrected distance visual acuity(UDVA), uncorrected intermediate visual acuity(UIVA), uncorrected near visual acuity(UNVA), total eye aberration, corneal aberration, and intraocular aberration within a 4 mm pupil diameter between the two groups at one month after surgery. In addition, we compared the changes in angle alpha before and after surgery between the two groups. The Mann-Whitney U test was used to analyze the data. Results The observation and control groups comprised 16 cases(16 eyes)and 17 cases(17 eyes), respectively. There was no statistical difference between the two groups of patients in terms of UDVA(P=0.286), UIVA(P=0.318), UNVA(P=0.449). High-order aberrations(P_{whole eye}=0.368,P_{cornea changes}=0.705), all intraocular aberration(P_{whole eye}=0.407,P_{cornea changes}=0.387), coma aberration(P_{whole eye}=0.957,P_{cornea changes}=0.599), intraocular clover aberration(P_{whole eye}=0.101, P_{cornea changes}=0.576), and spherical aberration(P_{whole eye}=0.785, P_{comea changes}=0.443)of the whole eye and cornea changes were not statistically significant; intraocular high-aberrations(P=0.387), intraocular clover aberration(P=0.139), all intraocular aberration(P=0.249), and coma aberration(P=0.33)were not statistically significant; intraocular spherical aberration(P=0.007)was statistically significant. There was no significant difference in angle alpha between the observation and control groups(P=0.985, P=0.890)before and after surgery. Conclusion Patients with an angle alpha of 0.5-0.8 mm can achieve the same surgical effect as that of patients with angle alpha less than or equal to 0.5 mm, by rotating the lens SBL-3 to make the visual axis land in the distal region.

Key words: Angle alpha, Multifocal intraocular lens, Cataract, Higher-order aberration, Vision