Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2026, Vol. 40 ›› Issue (3): 102-109.doi: 10.6040/j.issn.1673-3770.0.2025.291

• Original Article • Previous Articles     Next Articles

Refractive status of school-aged children aged 6-9 years in Yangpu District, Shanghai, 2022-2024: a cohort study

ZHU Xiqian, WANG Jia, SUN Zuxian, FENG Jianxiu, ZHANG Mengjia, ZHAO Ying, WANG Hong, JIANG Minmin   

  1. Shanghai Yangpu District Kongjiang Hospital/Shanghai Yangpu District Eye Disease Prevention and Treatment Institute, Shanghai 200093, China
  • Published:2026-05-22

Abstract: Objective To investigate the characteristics of refractive status changes and analyze the influencing factors of new-onset myopia among school-aged children aged 6-9 years in Yangpu District, Shanghai from 2022 to 2024, so as to provide scientific evidence for precise prevention and control of myopia by relevant government departments. Methods One primary school was randomly selected from each of the northern, central and southern areas of Yangpu District, Shanghai. All students in grades 1 to 3 from these three primary schools in September 2022 were enrolled as study subjects. Refractive examination data from 2022 to 2024 were collected, including uncorrected distance visual acuity test, non-cycloplegic autorefraction and axial length(AL)measurement. Normality of numerical data was tested by Kolmogorov-Smirnov method. Categorical data were described by frequencies, and comparisons between groups were performed using χ2 test. Generalized estimating equation was used to analyze differences between groups in repeated measurement data and factors influencing new-onset myopia. Results There were statistically significant differences in spherical equivalent(SE)and AL among different follow-up periods and baseline age groups(P<0.05). The detection rates of hyperopia, pre-myopia and myopia among different age groups at different periods showed statistically significant differences(P<0.05). Girls(OR=1.608, 95%CI: 1.218-2.124), pre-myopia(OR=4.447, 95%CI: 2.513-7.871)and baseline axial length(OR=1.505, 95%CI: 1.225-1.850)were independent risk factors for new-onset myopia(P<0.01). Conclusion The myopia rate among school-aged children aged 6-9 years in Yangpu District, Shanghai is relatively high, with insufficient hyperopia reserve being a prominent issue. The prevention and control checkpoint should be moved forward, refractive monitoring in preschool children should be strengthened, and active interventions should be implemented for children with pre-myopia.

Key words: School-age children, Refractive status, Hyperopia reserve, Pre-myopia, Myopia

CLC Number: 

  • R778
[1] 中华人民共和国教育部,国家卫生健康委员会,国家体育总局,等. 教育部等八部门关于印发《综合防控儿童青少年近视实施方案》的通知[EB/OL].(2018-08-31)[2024-10-02]. https://www.gov.cn/gongbao/content/2019/content_5361801.htm
[2] 季成叶. 现代儿童少年卫生学[M]. 2版. 北京: 人民卫生出版社, 2010
[3] Hou W, Norton TT, Hyman L, et al. Axial elongation in myopic children and its association with myopia progression in the correction of myopia evaluation trial[J]. Eye Contact Lens, 2018, 44(4): 248-259. doi:10.1097/icl.0000000000000505
[4] Chua SYL, Sabanayagam C, Cheung YB, et al. Age of onset of myopia predicts risk of high myopia in later childhood in myopic Singapore children[J]. Ophthalmic PhysiolOpt, 2016, 36(4): 388-394. doi:10.1111/opo.12305
[5] Haarman AEG, Enthoven CA, Tideman JWL, et al. The complications of myopia: a review and meta-analysis[J]. Invest Ophthalmol Vis Sci, 2020, 61(4): 49. doi:10.1167/iovs.61.4.49
[6] Jong M, Jonas JB, Wolffsohn JS, et al. IMI 2021 yearly digest[J]. Invest Ophthalmol Vis Sci, 2021, 62(5): 7. doi:10.1167/iovs.62.5.7
[7] 国家卫生健康委办公厅. 国家卫生健康委办公厅关于开展第二批儿童青少年近视防控适宜技术试点工作的通知[EB/OL].(2021-10-09)[2025-03-03]. http://www.nhc.gov.cn/jkj/s7934td/202110/0fc8a001d42345d9ac9b38842b295fe7.shtml
[8] Flitcroft DI, He MG, Jonas JB, et al. IMI-defining and classifying myopia: a proposed set of standards for clinical and epidemiologic studies[J]. Invest Ophthalmol Vis Sci, 2019, 60(3): M20. doi:10.1167/iovs.18-25957
[9] 杨彦帆. 儿童青少年近视防控取得实效[N]. 人民日报, 2021-07-14(013)
[10] 程天宇, 何鲜桂, 汪玲. 青少年屈光发育与青春期生长发育的研究进展[J]. 上海预防医学, 2019, 31(5): 338-343. doi:10.19428/j.cnki.sjpm.2019.19344 CHENG Tianyu, HE Xiangui, WANG Ling. Advances in research of adolescent refraction development during puberty[J]. Shanghai Journal of Preventive Medicine, 2019, 31(5): 338-343. doi:10.19428/j.cnki.sjpm.2019.19344
[11] 何鲜桂, 张欣, 许迅. 有序推进儿童青少年近视筛查建档和防控闭环管理[J]. 中华预防医学杂志, 2021, 55(4): 551-555. doi:10.3760/cma.j.cn112150-20201208-01435 HE Xiangui, ZHANG Xin, XU Xun. Orderly promoting myopia screening, refractive archives establishment, and the closed-loop management of myopia prevention and control for children and adolescents[J]. Chinese Journal of Preventive Medicine, 2021, 55(4): 551-555. doi:10.3760/cma.j.cn112150-20201208-01435
[12] 中华人民共和国国家卫生健康委员会. 《儿童青少年近视防控适宜技术指南(更新版)》及解读[EB/OL].(2021-10-13)[2025-03-02]. https://www.gov.cn/xinwen/2021-10/13/content_5642345.htm
[13] 孙祖贤, 冯彦清, 王宏, 等. 上海市杨浦区学龄前儿童视力的分析[J]. 上海预防医学, 2020, 32(2): 181-184. doi:10.19428/j.cnki.sjpm.2020.19043 SUN Zuxian, FENG Yanqing, WANG Hong, et al. Visual acuity in preschool children of Yangpu District in Shanghai[J]. Shanghai Journal of Preventive Medicine, 2020, 32(2): 181-184. doi:10.19428/j.cnki.sjpm.2020.19043
[14] 冯建秀, 姜敏敏, 冯彦清, 等. 上海市杨浦区3~6岁学龄前儿童屈光状态调查[J]. 中国初级卫生保健, 2023, 37(9): 27-30. doi:10.3969/j.issn.1001-568X.2023.09.0008 FENG Jianxiu, JIANG Minmin, FENG Yanqing, et al. Refraction of preschool children aged 3 to 6 years in Yangpu district of Shanghai[J]. Chinese Primary Health Care, 2023, 37(9): 27-30. doi:10.3969/j.issn.1001-568X.2023.09.0008
[15] YIN Y, LI L, WANG T, et al. Establishment of noncycloplegic methods for screening myopia and pre-myopia in preschool children[J]. Frontiers in Medicine, 2023, 10: 1291387. doi: 10.3389/fmed.2023.1291387
[16] Yu MK, Hu YY, Han M, et al. Global risk factor analysis of myopia onset in children: a systematic review and meta-analysis[J]. PLoS One, 2023, 18(9): e0291470. doi:10.1371/journal.pone.0291470
[17] 胡学敏, 周炼红, 金小琴, 等. 6~12岁儿童眼轴长度、角膜曲率半径及其比值与等效球镜的关系[J]. 中国斜视与小儿眼科杂志, 2021, 29(2): 8-11. doi:10.3969/J.ISSN.1005-328X.2021.02.003 HU Xuemin, ZHOU Lianhong, JIN Xiaoqin, et al. Relationship between axial length, corneal curvature radius, AL/CR ratio and refractive errors in children aged 6-12 years[J]. Chinese Journal of Strabismus & Pediatric Ophthalmology, 2021, 29(2): 8-11. doi:10.3969/J.ISSN.1005-328X.2021.02.003
[18] Peñaloza-Barbosa MI, Martinez-Perez C, Andreu-Vázquez C, et al. Spherical equivalent percentile curves in a Portuguese school-aged population[J]. J Clin Med, 2025, 14(20): 7262. doi:10.3390/jcm14207262
[19] Tao LX, Wang CX, Peng YY, et al. Correlation between increase of axial length and height growth in Chinese school-age children[J]. Front Public Health, 2022, 9: 817882. doi:10.3389/fpubh.2021.817882
[20] 马铭绅, 关文英, 李文萱, 等. 呼和浩特6~12岁儿童屈光状态特点及父母屈光状态对其的影响[J]. 中国临床医生杂志, 2021, 49(8): 995-998. doi:10.3969/j.issn.2095-8552.2021.08.036 MA Mingshen, GUAN Wenying, LI Wenxuan, et al. Characteristics of refractive status of children aged 6-12 in Hohhot and the influence of parents' refractive status on them[J]. Chinese Journal for Clinicians, 2021, 49(8): 995-998. doi:10.3969/j.issn.2095-8552.2021.08.036
[21] 茶健美, 闫芳冰, 张扬, 等. 7~12岁儿童屈光发育参数特点及对屈光状态的影响[J]. 昆明医科大学学报, 2025, 46(1): 87-92. doi:10.12259/j.issn.2095-610X.S20250111 CHA Jianmei, YAN Fangbing, ZHANG Yang, et al. Characteristics of refractive development parameters and their effects on refractive status in children aged 7-12 years[J]. Journal of Kunming Medical University, 2025, 46(1): 87-92. doi:10.12259/j.issn.2095-610X.S20250111
[22] 魏聪, 刘佳, 卢亚梅. 3~15岁儿童青少年眼轴与屈光状态变化分析[J]. 中国斜视与小儿眼科杂志, 2021, 29(4): 31-32. doi:10.3969/J.ISSN.1005-328X.2021.04.010 WEI Cong, LIU Jia, LU Yamei. Analysis of changes in the eye axis and refractive status of children and adolescents aged 3-15[J]. Chinese Journal of Strabismus & Pediatric Ophthalmology, 2021, 29(4): 31-32. doi:10.3969/J.ISSN.1005-328X.2021.04.010
[23] 中华预防医学会公共卫生眼科分会. 中国学龄儿童眼球远视储备、眼轴长度、角膜曲率参考区间及相关遗传因素专家共识(2022年)[J]. 中华眼科杂志, 2022, 58(2): 96-102. doi:10.3760/cma.j.cn112142-20210603-00267
[24] 邵洁, 黄蛟灵, 陈金枝, 等. 上海市3~16岁儿童屈光进展的时间与空间差异研究[J]. 中华全科医学, 2025, 23(1): 89-93. doi:10.16766/j.cnki.issn.1674-4152.003842 SHAO Jie, HUANG Jiaoling, CHEN Jinzhi, et al. A study on the temporal and spatial differences in refractive progression among children aged 3-16 in Shanghai[J]. Chinese Journal of General Practice, 2025, 23(1): 89-93. doi:10.16766/j.cnki.issn.1674-4152.003842
[25] Li YZ, Guo L, Zhang JY, et al. Trajectories of spherical equivalent refraction from grades 1 to 4 in Chinese children[J]. BMC Public Health, 2023, 23(1): 2500. doi:10.1186/s12889-023-17420-x
[26] 《眼轴长度在近视防控管理中的应用专家共识(2023)》专家组. 眼轴长度在近视防控管理中的应用专家共识(2023). 中华实验眼科杂志, 2024, 42(1): 1-11. doi:10.3760/cma.j.cn115989-20231010-00121
[27] 刘凌, 张美霞. 近视的药物治疗[J]. 山东大学耳鼻喉眼学报, 2021, 35(4): 123-128. doi:10.6040/j.issn.1673-3770.0.2020.313 LIU Ling, ZHANG Meixia. Drug therapy for myopia[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(4): 123-128. doi:10.6040/j.issn.1673-3770.0.2020.313
[28] Flitcroft DI, He MG, Jonas JB, et al. IMI-defining and classifying myopia: a proposed set of standards for clinical and epidemiologic studies[J]. Invest Ophthalmol Vis Sci, 2019, 60(3): M20. doi:10.1167/iovs.18-25957
[29] 项凯迪, 王菁菁, 潘臣炜, 等. 上海地区4~14岁儿童1年屈光进展及影响因素分析[J]. 中国学校卫生, 2022, 43(9): 1309-1313, 1318. doi:10.16835/j.cnki.1000-9817.2022.09.008 XIANG Kaidi, WANG Jingjing, PAN Chenwei, et al. Refractive progression among students aged 4-14 in Shanghai and associated factors[J]. Chinese Journal of School Health, 2022, 43(9): 1309-1313, 1318. doi:10.16835/j.cnki.1000-9817.2022.09.008
[30] Rozema J, Dankert S, Iribarren R, et al. Axial growth and lens power loss at myopia onset in Singaporean children[J]. Invest Ophthalmol Vis Sci, 2019, 60(8): 3091-3099. doi:10.1167/iovs.18-26247
[31] Castagno VD, Fassa AG, Carret MLV, et al. Hyperopia: a meta-analysis of prevalence and a review of associated factors among school-aged children[J]. BMC Ophthalmol, 2014, 14: 163. doi:10.1186/1471-2415-14-163
[32] 刘盛鑫, 杜蓓, 于军, 等. 天津市北辰区24930名7~12岁儿童屈光不正现况调查[J]. 现代疾病预防控制, 2023, 34(12): 933-936. doi:10.13515/j.cnki.hnjpm.1006-8414.2023.12.013 LIU Shengxin, DU Bei, YU Jun, et al. A cross-sectional survey on refractive errors in children aged 7-12 years in Beichen district of Tianjin[J]. Modern Disease Control and Prevention, 2023, 34(12): 933-936. doi:10.13515/j.cnki.hnjpm.1006-8414.2023.12.013
[33] Tang Y, Chen AM, Zou MJ, et al. Prevalence and time trends of refractive error in Chinese children: a systematic review and meta-analysis[J]. J Glob Health, 2021, 11: 08006. doi:10.7189/jogh.11.08006
[34] Williams SM, Sanderson GF, Share DL, et al. Refractive error, IQ and reading ability: a longitudinal study from age seven to 11[J]. Dev Med Child Neurol, 1988, 30(6): 735-742. doi:10.1111/j.1469-8749.1988.tb14635.x
[35] Dong W, Li YB, Liu CF, et al. A study on the status of myopia and pre-myopia among primary school students in different regions of Shaanxi Province, China[J]. Front Pediatr, 2025, 13: 1596389. doi:10.3389/fped.2025.1596389
[36] 邓益斌, 王晓银, 王惠敏, 等. 学龄前儿童近视临床前期相关因素分析[J]. 中国学校卫生, 2023, 44(6): 893-896. doi:10.16835/j.cnki.1000-9817.2023.06.022 DENG Yibin, WANG Xiaoyin, WANG Huimin, et al. Risk factors associated with pre-myopia among preschool children[J]. Chinese Journal of School Health, 2023, 44(6): 893-896. doi:10.16835/j.cnki.1000-9817.2023.06.022
[37] Shi ZW, Yang LH, Xu T, et al. Development of a risk score for myopia: a cohort study conducted among school-aged children in China[J]. Indian J Ophthalmol, 2024, 72(Suppl 2): S265-S272. doi:10.4103/ijo.ijo_2077_23
[38] 戚紫怡, 何鲜桂, 潘臣炜, 等. 上海地区6~8岁儿童近视前期流行病学调查[J]. 中国学校卫生, 2022, 43(9): 1314-1318. doi:10.16835/j.cnki.1000-9817.2022.09.009 QI Ziyi, HE Xiangui, PAN Chenwei, et al. Epidemiology of premyopia among children aged 6-8 in Shanghai[J]. Chinese Journal of School Health, 2022, 43(9): 1314-1318. doi:10.16835/j.cnki.1000-9817.2022.09.009
[39] 李玉兰, 童浩杰, 董鑫宇, 等. 2019年中国6~18岁汉族学生近视流行病学特征分析[J]. 中国校医, 2023, 37(7): 485-488 LI Yulan, TONG Haojie, DONG Xinyu, et al. Epidemiological characteristics of myopia among Han Chinese students aged 6-18 years in China in 2019[J]. Chinese Journal of School Doctor, 2023, 37(7): 485-488. doi:10.20161/j.cnki.32-1199/r.2023.07.003
[40] Liu LJ, Jiang DD, Li CC, et al. Relationship between myopia progression and school entrance age: a 2.5-year longitudinal study[J]. J Ophthalmol, 2021, 2021: 7430576. doi:10.1155/2021/7430576
[41] 廖娅, 陈鸿雁, 董磊, 等. 宿迁市2020年学龄儿童新发近视情况分析[J]. 国际眼科杂志, 2021, 21(11): 2001-2004. doi:10.3980/j.issn.1672-5123.2021.11.34 LIAO Ya, CHEN Hongyan, DONG Lei, et al. Analysis of new myopia among school-age children in Suqian City in 2020[J]. International Eye Science, 2021, 21(11): 2001-2004. doi:10.3980/j.issn.1672-5123.2021.11.34
[42] 雍政, 孙林, 张天薇, 等. 2 545名初中生新发近视情况及其影响因素研究[J]. 中国校医, 2022, 36(4): 256-259 YONG Zheng, SUN Lin, ZHANG Tianwei, et al. Study on new-onset myopia and its influencing factors in 2 545 junior middle school students[J]. Chinese Journal of School Doctor, 2022, 36(4): 256-259
[43] 王艳姣, 王菁菁, 倪梓涵, 等. 上海市儿童青少年周末户外活动水平及其与近视的关联[J]. 中国学校卫生, 2025, 46(1): 18-23. doi:10.16835/j.cnki.1000-9817.2025012 WANG Yanjiao, WANG Jingjing, NI Zihan, et al. Association of outdoor activity level on weekends and myopia among children and adolescents in Shanghai[J]. Chinese Journal of School Health, 2025, 46(1): 18-23. doi:10.16835/j.cnki.1000-9817.2025012
[1] SUN Fanmin, ZHANG Juanmei, GAO Jie, ZHAO Jun. Advances in Shh, PI3K/AKT, and MMP-2 pathways and correlations in myopia [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2026, 40(1): 142-148.
[2] DU Yifan, QI Linsong, LI Ying. Advancements in understanding how small incision lenticule extraction impacts ocular high order aberrations [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(1): 152-161.
[3] ZHANG Liyuan, GUO Yingzhuo, CHEN Jiao, WANG Hua, ZHONG Dingjuan. Clinical effect of 650-nm low-level red light in conjunction with orthokeratology in myopia control [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(5): 52-57.
[4] WANG Dongfang, ZHANG Qingyu, SONG Jike, BI Hongsheng. Assessment of reporting quality of randomized controlled trials on acupuncture preventing and controlling with myopia in children and adolescents based on CONSORT and STRICTA [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(5): 66-79.
[5] ZHANG Jinmu, GUO Bin, JIANG Wenjun, LIU Dongmei. Research progress on the role of M receptor signaling pathway in the occurrence and development of myopia [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(5): 160-164.
[6] ZHANG Liyuan, ZHONG Dingjuan, WANG Hua. Advancements in non-surgical management of myopia and choroidal research [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(4): 149-153.
[7] LI Yang, LIU Dong, CAO Wenjie. Meta-analysis of the effect of red-light therapy on spherical equivalent, axial length, and choroidal thickness in myopic children [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(3): 74-81.
[8] LU Song, XIA Yifan, LI Ziye, WEI Jing. Stickler's syndrome in children without retinal detachment:a case report and literature review [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(3): 97-101.
[9] HU Yarou, ZHAO Xinyu, WU Zhenquan, FAN Zixin, YU Zhen, LIU Yaling, CHEN Tingyi, ZENG Jian, ZHANG Guoming. Research progress on refractive status and ocular biometrics in preterm births [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(3): 144-150.
[10] WU Lili, QU Yi. Application of optical tomography angiography and artificial intelligence in choroidal neovascularization secondary to pathologic myopia [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(2): 144-149.
[11] YUSUFU·Maierhaba, ABULA·Kelimujiang, DING Lin, QIN Yanli, CHEN Xueyi. Fundus changes in high myopia cataract with posterior scleral staphyloma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(5): 107-114.
[12] YOU Ran, GUO Xiaoxiao, WANG Wei, CHEN Xi, WANG Yanling. Association of macular retinoschisis severity with choroidal parameters in patients with high myopia [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(3): 83-87.
[13] XIONG Pianpian, WANG Jialin, SUN Jiao, ZHOU Zhuohua, WANG Yanling. Analysis of retinal choroidal blood flow changes and correlation with tessellated fundus in highly myopic eyes [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(2): 114-121.
[14] ZHAO Hongxiao, ZHANG Han. Effect of optical amplification on measurement of ganglion cell complex [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(1): 105-109.
[15] DAI ChengOverview,LI BinzhongGuidance. Advances in multifocal soft corneal contact lens research [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(5): 100-105.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!