Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (3): 23-26.doi: 10.6040/j.issn.1673-3770.1.2019.003

• Invited Review • Previous Articles     Next Articles

Differential diagnosis of vestibular migraines and several common types of peripheral vertigo

Xiaolu LI()   

  1. Department of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University
  • Received:2019-01-01 Revised:2019-03-22 Online:2019-05-20 Published:2019-08-07
  • Contact: Xiaolu LI E-mail:lixlnj@qq.com

RichHTML

8

PDF (PC)

1366

Abstract:

Vestibular migraines (VMs) are a type of migraine with vestibular symptoms. Cases of VMs reportedly account for 16% of outpatients with vertigo in otolaryngology departments. They are listed as one of the important causes of so-called refractory dizziness and have been one of the research hotspots in balance disorder in recent years. The pathogenesis of VMs is not yet clear, and their clinical manifestations are diverse. Some manifestations are not only similar to those of otogenic vertigo, but even coexist in the same patient. In addition, with the rapid development of clinical vestibular function examination and evaluation methods, it is possible to perform preliminary evaluations of the semicircular canals, otolith organs, and vestibular nerve function. In this paper, the pathogenesis of VMs and differential diagnosis of four types of clinically common otogenic vertigo, including Meniere′s disease, vestibular neuronitis, benign paroxysmal positional vertigo, and vestibular paroxysmia are discussed, so as to provide clues for the accurate treatment of balance disorder.

Key words: Migraine, Vestibule, Vertigo, Diagnosis

CLC Number: 

  • R764.4
1 Van OmbergenA, Van RompaeyV, Van de HeyningP, et al. Vestibular migraine in an otolaryngology clinic: prevalence, associated symptoms, and prophylactic medication effectiveness[J]. Otol Neurotol, 2015, 36(1): 133-138. doi:10.1097/MAO.0000000000000596.
doi: 10.1097/MAO.0000000000000596
2 周丽丽, 王文昭, 杨月嫦, 等. 前庭性偏头痛的研究现状[J]. 临床耳鼻咽喉头颈外科杂志, 2016, 30(24): 1983-1986. doi:10.13201/j.issn.1001-1781.2016.24.024
doi: 10.13201/j.issn.1001-1781.2016.24.024
ZHOULili, WANGWenzhao, YANGYuechang, et al. Research status of vestibular migraine[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2016, 30(24): 1983-1986. doi:10.13201/j.issn.1001-1781.2016.24.024
doi: 10.13201/j.issn.1001-1781.2016.24.024
3 BrusichDJ, SpringAM, JamesTD, et al. Drosophila CaV2 channels harboring human migraine mutations cause synapse hyperexcitability that can be suppressed by inhibition of a Ca2+ store release pathway[J]. PLoS Genet, 2018, 14(8): e1007577. doi:10.1371/journal.pgen. 1007577.
doi: 10.1371/journal.pgen. 1007577
4 UnekawaM, IkedaK, TomitaY, et al. Enhanced susceptibility to cortical spreading depression in two types of Na+, K+-ATPase α2 subunit-deficient mice as a model of familial hemiplegic migraine 2[J]. Cephalalgia, 2018, 38(9): 1515-1524. doi:10.1177/0333102417738249.
doi: 10.1177/0333102417738249
5 FriedrichT, TavrazNN, JunghansC. ATP1A2 mutations in migraine: seeing through the facets of an ion pump onto the neurobiology of disease[J]. Front Physiol, 2016, 7: 239. doi:10.3389/fphys.2016.00239.
doi: 10.3389/fphys.2016.00239
6 HuangSS, SzallasiA. Transient receptor potential (TRP) channels in drug discovery: old concepts & new thoughts[J]. Pharmaceuticals (Basel), 2017, 10(3): E64. doi:10. 3390/ph10030064.
doi: 10. 3390/ph10030064
7 KarsanN, GonzalesEB, DussorG. Targeted acid-sensing ion channel therapies for migraine[J]. Neurotherapeutics, 2018, 15(2): 402-414. doi:10.1007/s13311-018-0619-2.
doi: 10.1007/s13311-018-0619-2
8 VerkestC, PiquetE, DiochotS, et al. Effects of systemic inhibitors of acid-sensing ion channels 1 (ASIC1) against acute and chronic mechanical allodynia in a rodent model of migraine[J]. Br J Pharmacol, 2018, 175(21): 4154-4166. doi:10.1111/bph.14462.
doi: 10.1111/bph.14462
9 HiekkalaME, VuolaP, ArttoV, et al. The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families[J]. Cephalalgia, 2018, 38(12): 1849-1863. doi:10.1177/0333102418761041.
doi: 10.1177/0333102418761041
10 RenL, DhakaA, CaoYQ. Function and postnatal changes of dural afferent fibers expressing TRPM8 channels[J]. Mol Pain, 2015, 11: 37. doi:10.1186/s12990-015-0043-0.
doi: 10.1186/s12990-015-0043-0
11 DussorG, CaoYQ. TRPM8 and migraine[J]. Headache, 2016, 56(9): 1406-1417. doi:10.1111/head.12948.
doi: 10.1111/head.12948
12 余力生, 司峰志, 马鑫, 等. 梅尼埃病和前庭性偏头痛[J]. 临床耳鼻咽喉头颈外科杂志, 2016, 30(12): 925-927. doi:10.13201/j.issn.1001-1781.2016.12.001
doi: 10.13201/j.issn.1001-1781.2016.12.001
YULisheng, SIFengzhi, XinMA , et al. Meniere disease and vestibular migraine[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2016, 30(12): 925-927. doi:10.13201/j.issn.1001-1781.2016.12.001
doi: 10.13201/j.issn.1001-1781.2016.12.001
13 InoueA, EgamiN, FujimotoC, et al. Vestibular evoked myogenic potentials in vestibular migraine: do they help differentiating from menière's disease?[J]. Ann Otol Rhinol Laryngol, 2016, 125(11): 931-937. doi:10.1177/0003489416665192.
doi: 10.1177/0003489416665192
14 余孝君. 女性前庭性偏头痛与围绝经期血清性激素水平的关系[J]. 广东医学, 2018, 39(15): 2339-2341. doi:10.13820/j.cnki.gdyx.2018.15.007
doi: 10.13820/j.cnki.gdyx.2018.15.007
15 YolluU, Uluduz DU, YilmazM, et al. Vestibular migraine screening in a migraine-diagnosed patient population, and assessment of vestibulocochlear function[J]. Clin Otolaryngol, 2017, 42(2): 225-233. doi:10.1111/coa. 12699.
doi: 10.1111/coa. 12699
16 吕亚峰, 张道宫, 樊兆民, 等. 前庭神经炎患者前庭功能损伤的频率和部位特征分析[J]. 临床耳鼻咽喉头颈外科杂志, 2016, 30(8): 602-605. doi:10.13201/j.issn.1001-1781.2016.08.004.
doi: 10.13201/j.issn.1001-1781.2016.08.004
LVYafeng, ZHANGDaogong, FANZhaomin, et al. Frequency and position characteristics of the vestibular dysfunction in vestibular neuritis patients[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2016, 30(8): 602-605. doi:10.13201/j.issn.1001-1781.2016.08.004.
doi: 10.13201/j.issn.1001-1781.2016.08.004
17 林细康, 李晓璐. 眼性前庭诱发肌源电位对眩晕定位诊断的价值探讨[J/OL]. 中华临床医师杂志(电子版), 2014, 8(3): 411-414. .
LINXikang, LIXiaolu. The value to localization diagnosis for vertigo of ocular vestibular evoked myogenic potential[J/OL]. Chinese Journal of Clinicians (Electronic Edition), 2014, 8(3): 411-414. .
18 KangWS, LeeSH, YangCJ, et al. Vestibular function tests for vestibular migraine: clinical implication of video head impulse and caloric tests[J]. Front Neurol, 2016, 7: 166. doi:10.3389/fneur.2016.00166.
doi: 10.3389/fneur.2016.00166
19 林细康, 李晓璐. 后半规管良性阵发性位置性眩晕发作与头部睡眠姿势相关性分析[J]. 中国耳鼻咽喉头颈外科, 2017, 24(5):242-244. doi:10.16066/j.1672-7002.2017.05.007
doi: 10.16066/j.1672-7002.2017.05.007
LINXikang, LIXiaolu. Correlation analysis of the incidence and head position in posterior semicircular canal benign paroxysmal positional vertigo[J]. Chinese Archives of Otolaryngology-Head and Neck Surgery, 2017, 24(5): 242-244. doi:10.16066/j.1672-7002.2017.05.007
doi: 10.16066/j.1672-7002.2017.05.007
20 WhitneySL, AlghwiriA, AlghadirA. Physical therapy for persons with vestibular disorders[J]. Curr Opin Neurol, 2015, 28(1): 61-68. doi:10.1097/WCO. 0000000000-000162.
doi: 10.1097/WCO. 0000000000-000162
21 BrandtT, StruppM, DieterichM. Vestibular paroxysmia: a treatable neurovascular cross-compression syndrome[J]. J Neurol, 2016, 263(Suppl 1):S90-S96. doi:10.1007/s00415-015-7973-3.
doi: 10.1007/s00415-015-7973-3
[1] LYU Dan, LI Ruzhen, LIU Mingqiu, MENG Xinyu, LI Junyi. Incidence and correlation of anxiety, depression, and sleep disorders in patients with different types of benign paroxysmal positional vertigo [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2026, 40(3): 62-67.
[2] CHENG Zhuo, LIANG Hui, XING Lumin. Research progress and prospect analysis of deep learning technology in the application of pharyngeal and laryngeal endoscopy [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2026, 40(1): 112-119.
[3] LIU Yijie, LU Xiuzhen, WU Qiuxin. Research rogress of exosomes in the pathogenesis, diagnosis and treatment in ophthalmic diseases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2026, 40(1): 135-141.
[4] LI Zan, LU Qi, SHEN Weidong, HOU Zhaohui, WU Nan. Clinical diagnosis and treatment features of 18 cases of necrotizing otitis externa [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(6): 17-22.
[5] MA Xiaobao, SHEN Jiali, YANG Jun, CHEN Jianyong, ZHU Songhuan. Exploring the clinical implications of normal VOR gain with refixation saccades in lateral canal [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(6): 40-45.
[6] LIU Ziqi, HUANG Jiali, WANG Liqin, CHEN Xi, ZHANG Liqing, ZHOU Han. Application of narrow band imaging endoscopy combined with voice acoustic analysis in the differential diagnosis of vocal cord leukoplakia [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(6): 87-96.
[7] SUN Shuo, YUAN Tiejun, CHEN Yao, QI Lingling, HAN Rongrong. Misdiagnosis of lingual tuberculosis: a case report and literature veview [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(6): 138-143.
[8] LIU Nanxian, YANG Zeyin, HAN Lin, ZHANG Aiying, ZHAO Yuliang, XUE Jing, SUN Yijun, SHAO Yongliang. Significance of video-EEG in the diagnosis of recurrent vertigo in children [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(5): 20-25.
[9] ZHOU Zhihang, LIU Suru, ZHOU Jing, CHEN Dan, YANG Jiajing, LIU Rui, ZHOU Li. Etiology and treatment advances in glottic insufficiency [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(3): 97-103.
[10] ZHAO Zhen, ZHENG Guiliang, WANG Jun, ZHANG Bingwen. Analysis of the curative efficacy of low-frequency vibration shear stress on patients with unilateral vestibular dysfunction [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(1): 23-28.
[11] WANG Boshen, LENG Hui, SUN Haibo. Co-expressing genes in Meniere's disease and vestibular migraine and molecular docking prediction of gastrodin [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(1): 29-40.
[12] WU Wei, WANG Lei, CHEN Sheng, LI Lianyong, WANG Gang. Multidisciplinary research and advances in gastro-oesophageal reflux disease [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(6): 1-14.
[13] LIU Lianlian, LI Jinrang. Obstructive sleep apnea and laryngopharyngeal reflux [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(6): 15-22.
[14] LI Gui, YANG Yanli, LI Donghai, YAN Xiuying. Adult orbital xanthogranulomatous disease with clinicopathological analysis report and literature review [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(5): 80-85.
[15] PENG Yuting, LI Jianhao, WANG Yan. Orbital apex syndrome secondary to nasal-orbital-skull base malignant tumor: a case report and literature review [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(5): 105-111.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd