Abstract: To observe the infl uence of irrigation at nasal cavity with Bidouyan oral liquid on the ultrastructure of nasal mucocilia after endoscopic sinus surgery(ESS) in patients with chronic rhinosinusitis. Methods： Thirty patients with chronic rhinosinusitis were dealt with endoscopic sinus surgery and then divided into three groups at random. Group A: 500?ml physiologic saline adding 20?ml Bidouyan oral liquid was applied for nasal cavity irrigation for 3 days to 3 months after ESS, twice each week. Group B: 500?ml physiologic saline adding 80?000?U gentamycin and 5?mg dexamethasone solution was applied for nasal cavity irrigation after ESS, twice each week. Group C: 500?ml physiologic saline alone was applied for nasal cavity irrigation after surgery. All the patients accepted saccharin test before surgery and three months after surgery, and 2 healthy cases were observed as controls. Results: The mucosa was examined with electron microscope before surgery and three months after surgery. After surgery, the cilia arranged in order and densely, and the structure of “9+2" canaliculus was normal. Conclusion: Irrigation at nasal cavity with Bidouyan oral liquid after surgery can accelerate the recovering of nasal mucosa.

Key words: endoscopy, Surgical procedures, Sinusitis, Nasal mucosa, Nasal cavity