Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (5): 192-197.doi: 10.6040/j.issn.1673-3770.0.2022.319

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Application of metagenomic next-generation sequencing in cervical necrotizing fasciitis

QIN Nian, XIAO Yu, ZHANG Kunyi, LI Jingkun, XIAO Xuping   

  1. Department of Otorhinolaryngology & Head and Neck Surgery, the First Affiliated Hospital of Hunan Normal University /Hunan Provincial Peoples Hospital, Changsha 410005, Hunan, China
  • Published:2023-10-13

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Abstract: Metagenomic next generation sequencing is a novel microbiological diagnostic technique that does not rely on isolation and cultivation of pathogens. In theory, it can promptly detect all pathogen information in samples and has been used to diagnose many infectious diseases. Cervical necrotizing fasciitis is a fatal infectious disease with a high mortality rate. Cervical necrotizing fasciitis is one of the critical diseases in otorhinolaryngology head and neck surgery. Rapid detection of the infection causing pathogens is essential in improving the rescue success rate and prognosis. This article analyzes the application progress of the metagenomic next generation sequencing in necrotizing cervical fasciitis, to provide a new diagnostic basis for the early detection of the infection.

Key words: Necrotizing fasciitis, Cervical, Metagenomic next generation sequencing, Diagnosis

CLC Number: 

  • R762
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