焦虑抑郁对阻塞性睡眠呼吸暂停低通气综合征患者夜间血压波动的影响

doi:10.6040/j.issn.1673-3770.0.2019.418

摘要/Abstract

摘要： 目的探讨焦虑和/或抑郁以及认知功能下降对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者夜间血压波动的影响。方法收集自 2018年8月至2019年5月就诊于山东大学齐鲁医院(青岛)行多导睡眠呼吸监测并能够配合完成汉密尔顿抑郁量表、焦虑自评量表、抑郁自评量表评估的154例OSAHS患者为研究对象。其中81例确诊为焦虑和/或抑郁状态并OSAHS,设为实验组;73例为单纯OSAHS,无相关精神症状,设为对照组。所有患者行整夜多导睡眠监测,分别记录患者多导睡眠监测各项数据。分析各组间数据,进行统计学分析。结果呼吸紊乱指数>30次/h重度OSAHS患者,实验组收缩压最高值、收缩压幅度高于对照组,差异具有统计学意义。结论焦虑和/或抑郁等不良心理情绪以及认知功能下降会影响重度OSAHS患者收缩压的波动范围,睡眠监测过程中需密切关注焦虑和/或抑郁并重症OSAHS患者夜间血压变化,预防心血管并发症出现。

关键词: 阻塞性睡眠呼吸暂停低通气综合征, 焦虑抑郁, 夜间血压波动

Abstract: Objective To investigate the effects of anxiety and/or depression and cognitive decline on nocturnal blood pressure fluctuations in patients with obstructive sleep apnea hypopnea syndrome(OSAHS). Methods The study group included 81 patients with anxiety and/or depression and OSAHS, who were treated in Qilu Hospital of Shandong University(Qingdao)from August 2018 to May 2019, while 73 patients with OSAHS only were selected as controls. All patients were able to complete the Hamilton depression scale, self-rating anxiety scale, and self-rating depression scale evaluations and underwent overnight polysomnography(PSG)using SOMNOmedics V6. Simultaneously, PSG monitoring data were recorded. Patients were divided into three groups-mild, moderate, and severe-according to the apnea hypopnea index. Results The highest systolic blood pressure and systolic amplitude of the study group were significantly higher than those of the control group, and the differences were statistically significant. Conclusion Adverse psychological emotional states, such as anxiety and/or depression, and cognitive decline will affect the range of fluctuation of systolic blood pressure in patients with severe OSAHS. During sleep monitoring, it is necessary to pay close attention to changes in nocturnal blood pressure in patients with anxiety and/or depression and severe OSAHS to prevent cardiovascular complications.

Key words: Obstructive sleep apnea hypopnea syndrome, Anxiety and/or depression, Nocturnal fluctuation of blood pressure

中图分类号:

R766.7

李晓, 袁英, 李延忠, 王岩, 杨珂, 孙永强, 于学民, 王宁, 王磊. 焦虑抑郁对阻塞性睡眠呼吸暂停低通气综合征患者夜间血压波动的影响[J]. 山东大学耳鼻喉眼学报, 2019, 33(6): 68-71.

LI Xiao, YUAN Ying, LI Yanzhong, WANG Yan, YANG Ke, SUN Yongqiang, YU Xuemin, WANG Ning, WANG Lei. Effects of anxiety and depression on nocturnal blood pressure fluctuation in patients with obstructive sleep apnea hypopnea syndrome[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(6): 68-71.

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