山东大学耳鼻喉眼学报 ›› 2018, Vol. 32 ›› Issue (3): 10-13.doi: 10.6040/j.issn.1673-3770.1.2018.008
娄鸿飞1,2,王成硕1,2
LOU Hongfei1,2, WANG Chengshuo1,2
摘要: 慢性鼻-鼻窦炎(CRS)是由不同发病机制、不同临床表现、不同预后的鼻窦炎症组成的异质性疾病谱,分为不同的表型和内在型。CRS是鼻科临床诊疗的难治性疾病,在对本地区患者进行临床表型和内在型分型的基础上,针对不同分型患者制定针对性的诊疗策略,这是精准医疗观念指引下的CRS临床诊疗发展方向。
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[1] Rosenfeld RM, Piccirillo JF, Chandrasekhar SS, et al. Clinical practice guideline(update): adult sinusitis[J]. Otolaryngol Head Neck Surg, 2015, 152(2 Suppl):S1-S39. [2] Fokkens W, Lund V, Mullol J. European position paper on rhinosinusitis and nasal polyps 2007[J]. Rhinol Suppl, 2007, 20:1-136. [3] Shi JB, Fu QL, Zhang H, et al. Epidemiology of chronic rhinosinusitis: results from a cross-sectional survey in seven Chinese cities[J]. Allergy, 2015, 70(5):533-539. [4] Meltzer EO, Hamilos DL, Hadley JA, et al. Rhinosinusitis: establishing definitions for clinical research and patient care[J]. J Allergy Clin Immunol, 2004, 114(6 Suppl):155-212. [5] Fokkens W, Lund V, Bachert C, et al. EAACI position paper on rhinosinusitis and nasal polyps executive summary[J]. Allergy, 2005, 60(5):583-601. [6] 中华医学会耳鼻咽喉科学分会,中华耳鼻咽喉科杂志编辑委员会. 慢性鼻窦炎鼻息肉临床分型分期及内窥镜鼻窦手术疗效评定标准(1997年, 海口)[J].中华耳鼻咽喉科杂志,1998,33(3):134. [7] 中华耳鼻咽喉头颈外科杂志编委会,中华医学会耳鼻咽喉头颈外科学分会鼻科学组. 慢性鼻-鼻窦炎诊断和治疗指南(2008年,南昌)[J]. 中华耳鼻咽喉头颈外科杂志, 2009, 44(1):6-7. Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery; Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association.Guidelines for diagnosis and treatment of chronic rhinitis and nasal sinusitis(2008, Nanchang)[J]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 2009, 44(1):6-7. [8] 中华耳鼻咽喉头颈外科杂志编辑委员会鼻科组,中华医学会耳鼻咽喉头颈外科学分会鼻科学组. 慢性鼻-鼻窦炎诊断和治疗指南(2012年,昆明)[J]. 中华耳鼻咽喉头颈外科杂志, 2013,48(2):92-94. Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery; Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association.Guidelines for diagnosis and treatment of chronic rhinosinusitis(2012, Kunming)[J]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 2013, 48(2):92-94. [9] Soler ZM, Hyer JM, Rudmik L, et al. Cluster analysis and prediction of treatment outcomes for chronic rhinosinusitis[J]. J Allergy Clin Immunol, 2016, 137(4):1054-1062. [10] Lal D, Hopkins C, Divekar RD. SNOT-22-based clusters in chronic rhinosinusitis without nasal polyposis exhibit distinct endotypic and prognostic differences[J]. Int Forum Allergy Rhinol, 2018 Feb 13. doi: 10.1002/alr.22101.[Epub ahead of print] [11] Wu D, Bleier BS, Li L, et al. Clinical Phenotypes of Nasal Polyps and Comorbid Asthma Based on Cluster Analysis of Disease History[J]. J Allergy Clin Immunol Pract, 2017 Oct 31. pii: S2213-2198(17)30746-8. doi: 10.1016/j.jaip.2017.09.020.[Epub ahead of print] [12] Fokkens WJ, Lund VJ, Mullol J, et al. European Position Paper on Rhinosinusitis and Nasal Polyps 2012[J]. Rhinol Suppl, 2012, 50(23):1-298. [13] Zhang N, Van Zele T, Perez-Novo C, et al. Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease[J]. J Allergy Clin Immunol, 2008, 122(5):961-968. [14] Van Bruaene N, Perez-Novo CA, Basinski TM, et al. T-cell regulation in chronic paranasal sinus disease[J]. J Allergy Clin Immunol, 2008, 121(6):1435-1441.e3. [15] Bachert C, Wagenmann M, Hauser U, et al. IL-5 synthesis is upregulated in human nasal polyp tissue[J]. J Allergy Clin Immunol, 1997, 99(6 Pt 1):837-842. [16] Watelet JB, Bachert C, Claeys C, et al. Matrix metalloproteinases MMP-7, MMP-9 and their tissue inhibitor TIMP-1: expression in chronic sinusitis vs nasal polyposis[J]. Allergy, 2004, 59(1):54-60. [17] Claeys S, Van Hoecke H, Holtappels G, et al. Nasal polyps in patients with and without cystic fibrosis: a differentiation by innate markers and inflammatory mediators[J]. Clin Exp Allergy, 2005, 35(4):467-472. [18] Lou H, Meng Y, Piao Y, et al. Cellular phenotyping of chronic rhinosinusitis with nasal polyps[J]. Rhinology, 2016, 54(2):150-159. [19] Adnane C, Adouly T, Khallouk A, et al. Using preoperative unsupervised cluster analysis of chronic rhinosinusitis to inform patient decision and endoscopic sinus surgery outcome[J]. Eur Arch Otorhinolaryngol, 2017, 274(2):879-885. [20] Wang X, Zhang N, Bo M, et al. Diversity of TH cytokine profiles in patients with chronic rhinosinusitis: A multicenter study in Europe, Asia, and Oceania[J]. J Allergy Clin Immunol, 2016, 138(5):1344-1353. [21] Tomassen P, Vandeplas G, Van Zele T, et al. Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers[J]. J Allergy Clin Immunol, 2016, 137(5):1449-1456.e1444. [22] Turner JH, Chandra RK, Li P, et al. Identification of clinically relevant chronic rhinosinusitis endotypes using cluster analysis of mucus cytokines[J]. J Allergy Clin Immunol, 2018 Feb 13. pii: S0091-6749(18)30224-0. doi: 10.1016/j.jaci.2018.02.002.[Epub ahead of print] [23] Liao B, Liu JX, Li ZY, et al. Multidimensional endotypes of chronic rhinosinusitis and their association with treatment outcomes[J]. Allergy, 2018 Jan 13. doi: 10.1111/all.13411.[Epub ahead of print] |
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